Báo cáo hóa học: " Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies Richard Paul Junghan" pdf
Báo cáo hóa học: " Strategy Escalation: An emerging paradigm for safe clinical development of T cell gene therapies Richard Paul Junghan" pdf
... patient can safely be treated, then one may reasonably advance to more potent Strategies with a rationale for safety. Further, it is clear that safety with an antibody is not the same as safety ... of such a discussion from the current state of the art for designer T cell therapies, counseling against the most intensive Strategies for untested antigen targets. If by an earl...
Ngày tải lên: 18/06/2014, 16:20
báo cáo hóa học: " Time and frequency domain methods for quantifying common modulation of motor unit firing patterns" pot
... suited to quantifying the strength of a broad band drive into a single index. This proves useful in quantitative, comparitive analyses of the common behavior of MUs such as statistical tests that investigate ... number of data segments employed and X 1n (f) and X 2n (f) are the dis- crete Fourier transforms of the nth data segments of x 1 (t) and x 2 (t) . This estimate is...
Ngày tải lên: 19/06/2014, 10:20
Báo cáo hóa học: " Adenoviruses with an avb integrin targeting moiety in the fiber shaft or the HI-loop increase tumor specificity without compromising antitumor efficacy in magnetic resonance imaging of colorectal cancer metastases" pdf
... were performed by SP. SLA, TT and SP analyzed the data, interpreted the results and wrote the paper. All authors have contributed to, seen and approved the manuscript. Competing interests The authors ... metastasis of WT-RGD treated animal one day before treatment and (D) on day 35 after WT-RGD treatment. Lavilla-Alonso et al. Journal of Translational Medicine 2010, 8:80 http://www.transl...
Ngày tải lên: 18/06/2014, 16:20
Báo cáo hóa học: " HPV vaccine: an overview of immune response, clinical protection, and new approaches for the future" pdf
... neutralizing antibodies work? Theansweristhatthequalityandthequantityofthe immune response generated by the vaccine is different to those of the natural infection. Themaincharacteristicsoftheimmuneresponsefol- lowing ... venuti@ifo.it 2 Lab. Virology, National Cancer Institute Regina Elena of Rome, Italy Full list of author information is available at the end of the article Mariani an...
Ngày tải lên: 18/06/2014, 16:20
Tài liệu Báo cáo khoa học: Angiopoietin-like proteins: emerging targets for treatment of obesity and related metabolic diseases pptx
... conditions. Suppression of ANGPTL2 as an effective strategy against obesity-related insulin resistance It is well known that lifestyle intervention is the best strategy to overcome obesity and related metabolic ... focus on the roles of ANGPTL2 and ANGPTL6 ⁄ AGF in obes- ity and related metabolic diseases, and discuss whether these ANGPTLs could be targets for the prevention and t...
Ngày tải lên: 14/02/2014, 22:20
báo cáo hóa học:" Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin" docx
... compared to that of parent CNE2 cells and CNE2 cells with negative control construct. These results suggest that ABCC2 may play an important role in NPC resistant to cisplatin. Competing interests The ... performed to assess the viability of the transfected cells [18]. Analysis of ABCC2 mRNA levels by quantitative RT-PCR Total RNA of these cell clones was isolated and quantita- ti...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Tremorgenesis: a new conceptual scheme using reciprocally innervated circuit of neurons" pptx
... valid model of rest tremor. Trying to isolate mechanisms of tremor from four-footed animals and to extrapolate them to human beings is not straight-forward. Developments of convenient and reproducible ... currents resulted in alternating bursts of action potentials in the neurons innervating the sets of agonist and antagonist muscles. The frequency of the simulated tremor was very...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Stem cells from umbilical cord blood do have myogenic potential, with and without differentiation induction in vitro" pdf
... CD34+ stem cells to interact and differentiate into muscle cells when in direct contact with human DMD/DMB myob- lasts, and their potential to restore the absent protein. Our results show CD34+ cells ... differentiation of transplanted cells. In past decades, human umbilical cord blood (HUCB) has been explored as an alternative source to BM for cell transplantation and therapy because...
Ngày tải lên: 18/06/2014, 15:20
báo cáo hóa học:" Aberrant expression and potency as a cancer immunotherapy target of alpha-methylacyl-coenzyme A racemase in prostate cancer" pptx
... CTL induction, killing assays and drafted the manuscript. TT and YH participated in the design of the study and performed the evaluation of the data. TT helped to draft the manuscript. YH contributed ... that T- cells with strong reactivity to AMACR might have tolerance to the antigenic stimulation. Thus, further studies are required to increase the cytotoxic potential of the AMACR-spe...
Ngày tải lên: 18/06/2014, 15:20
Báo cáo hóa học: "Exhaustive expansion: A novel technique for analyzing complex data generated by higherorder polychromatic flow cytometry experiments" pot
... frequencies of the relevant subsets. The output was then loaded into a relational database (MySQL), and standard SQL statements and graphing utilities were used to interro- gate the data. Statistical tests ... aggregate sets or supersets from input data, and outputs both the relative set name and the percentage of cells in both the newly derived sets and the original sets. The percentage...
Ngày tải lên: 18/06/2014, 16:20