báo cáo hóa học:" KSP inhibitor ARRY-520 as a substitute for Paclitaxel in Type I ovarian cancer cells" potx

... give various final con- centrations as described in the results section. Each exper- iment was done in triplicate. Caspase-3/7, -8, and -9 activity assay Caspase activity was measured using Caspase-Glo™ ... population would be bene- ficial for the treatment of ovarian cancer patients. ARRY-520 is an inhibitor of the mitotic kinesin, KSP. KSP inhibition prevents bipolar spin...

Ngày tải lên: 18/06/2014, 15:20

... Erlandson RF: Application of robotic/mechatronic systems in special education, rehabilitation therapy, and vocational training: A paradigm shift”. IEEE Transactions on Rehabilitation Engineering 1995, ... system at baseline and at dis- charge. An occupational therapist blinded to patient allocation administered the CAHAI-7 and the CMSA at admission and discharge. At discharge, participant...

Ngày tải lên: 19/06/2014, 08:20

... Jaureguibeitia - ajaureguibeitia@pharmakine.com; Aritz Lopategi - aritzlopategi@yahoo.es; I igo Martínez - inigo.martinez@fagmed.uit.no; Lorea Mendoza - lmendoza@pharmakine.com; Francisco J Muruzabal ... of this integrin contributes to hepatic invasion and metastasis of lymphoma, leukemia and breast cancer cells [22,23]; that LFA-1 blockade using specific antibod- ies can inhibit the hepa...

Ngày tải lên: 18/06/2014, 15:20

... subdimension, indicating lim- ited performance and physical activities. Residents who no longer have physical ability but have mental ability can find other areas in life that are meaningful: the disability paradox. ... carrying out a conversation and had been residing in the NHs for at least 6 months. We defined mentally intact as having a Clinical Dementia Rating (CDR) ≤ 0.5 [22...

Ngày tải lên: 18/06/2014, 19:20

... European Chapter of the Association for Computational Linguis- tics (EACL-06), Trento, Italy. K. Sima’an. 1996. Computational complexity of proba- bilistic disambiguation by means of tree-grammars. In Proceedings ... 2008. c 2008 Association for Computational Linguistics Regular tree grammars as a formalism for scope underspecification Alexander Koller ∗ a. koller@ed.ac.uk ∗ Univ...

Ngày tải lên: 23/03/2014, 17:20

... questionnaire as a main convergence criterion because it's two dimensional scale is measuring the adaptive capacitiy. "Ability to Change Behaviour", and "Achieve Satisfaction and ... the topics of meaningfulness, manageability and resilience in dealing with cancer disease and formation of perspective. According to our experience in cancer patients, we also inte...

Ngày tải lên: 18/06/2014, 18:20

... rat- ings for regurgitation, heartburn, and dyspepsia at base- line and at visit 2. A positive correlation was found between physician severity ratings and RDQ scale scores, which increased with ... +7. Other assessments At both clinic visits, a clinical trial assessment interview and a physical examination were conducted by the inves- tigators. Patients were asked about the severity...

Ngày tải lên: 18/06/2014, 22:20

... Map Building and Localization with Landmark Validation. International Journal of Pattern Recognition and Artificial Intelligence 2002, 16:361-374. 12. Diosi A, Kleeman L: Advanced Sonar and Laser ... (Consejo Nacional de Investigaciones Científicas y Técnicas). Author details 1 Institute of Automatics, National University of San Juan, Argentina. 2 Medical Technology Department, National Univ...

Ngày tải lên: 19/06/2014, 08:20

... TPD52 downregulation induces cell death, we determined the involvement of caspase activation and mitochondria membrane depolarization. In many cell types, activa- tion of procaspase-3 is a distinguishing ... regulation of apoptosis and proliferation. Its association with cell migration suggests a role in tumor dissemination. Because the PKB ⁄ Akt pathway is the central pathway involve...

Ngày tải lên: 30/03/2014, 02:20

... decreased phosphorylation of FAK was implicated in dasatinib-mediated inhibition of migration and invasion in melanoma cells. Conclusion: Dasatinib has both anti-proliferative and anti-invasive effects in melanoma ... dasatinib on invasion and migration were examined in two invasive cell lines, one dasatinib sensi- tive (HT144) and one resistant cell line (Sk-Mel-28). Dasatinib signif...

Ngày tải lên: 18/06/2014, 15:20