báo cáo hóa học:" The cancer secretome: a reservoir of biomarkers" doc
Báo cáo khoa học: "The Formal and Processing Models of CLG" docx
... conference of the European Chapter of the ACL, ACL. 14] Pollard, Carl J. and Ivan A. Sag, 1987. "Information-Based Syntax and Semantics 1: Fundamentals", Center for the Study of Language ... a grammar formalism based on an equational theory, to an algorithm for a formalism with complex constraints attached to rules. Assume a countable set V of variables x, y, z, and a countable ... form and the lazy evaluation of complex constraints. The choice of constrained terms instead of the more common sets of constraints is motivated by methodological rather than theoretical reasons....
- 6
- 281
- 0
Tài liệu Báo cáo khoa học: ˚ The 1.8 A crystal structure of a proteinase K-like enzyme from a psychrotroph Serratia species docx
... [18]. The biophysical characteri-zation of SPRK did not reveal the classical cold adap-ted features [19], but still initial comparative studiesshowed that the catalytic turnover was at least ... SPRK also has an aspar-tic acid residue at position at 200, and with the sameconformation as in the two other structures, butAsp200 forms a salt bridge to Lys253 (Ala253 andAsn250 in PRK and ... reported.Results and discussionCrystallization, data collection and refinementCrystals of the catalytic domain of the Serratia prote-inase K (SPRK) grew within a few days to thin hexa-gonal plates growing...
- 11
- 551
- 0
Tài liệu Báo cáo khóa học: The PAS fold A redefinition of the PAS domain based upon structural prediction ppt
... thaliana proteins alsocontain a PAC motif, and conversely that all PAC-annotated A. thaliana proteins contain a PAS domain.Therefore, in the case of A. thaliana,thePASandPACmotifs are inseparable, ... that not all six structures contain a PAS aswell as a PAC motif, according to the PFAM database(Fig. 1D and Table 1). Each of the 958 PAS domains wasmodelled against each of the six template structurespresented ... future.3Arabidopsis,Escherichia,CaenorhabditisandAzotobacter– a case studySome of the PAS domains have been analysed in detail.We chose four representative organisms from the animal,bacterial and plant kingdoms, A. thaliana,...
- 11
- 592
- 0
Báo cáo khoa học: The natural mutation by deletion of Lys9 in the thrombin A-chain affects the pKa value of catalytic residues, the overall enzyme’s stability and conformational transitions linked to Na+ binding pdf
... experimentally.In analogy with the values calculated in enzymaticexperiments, an increase of % 0.5 pK units of the His57 in DK9 mutant was also calculated analyzing the NAPAP data set (Table 1C). ... DK9thrombins. The change in pK a value of the catalytic His residuein the mutant thrombin implies that the deletion of Lys9 allosterically affects the conformational state of relevant domains of the catalytic ... (2–4). Global and simul-taneous analysis of the experimental data by grafit soft-ware allowed computation of the pK a values of the twogroups both in the free and substrate-bound species of thrombin...
- 11
- 553
- 0
Báo cáo khoa học: Missense mutations as a cause of metachromatic leukodystrophy Degradation of arylsulfatase A in the endoplasmic reticulum potx
... and 25 min after synthesis. The maturation of these late forming epitopes is accompanied by a further maturation of epitopes A2 and A5 . After25 min of chase, precipitation with mAbs A2 and A5 is ... mechanisms causeASA deficiency. In about half of the examined cases the mutant enzymes are retained in the ER [2,9,10], in the other half, enzymes can leave the ER and be degradedafter arrival ... caused by the deficiency of arylsulfatase A (ASA). This enzyme catalyses the firststep in the degradation pathway of the glycosphingo-lipid 3-O-sulfogalactosylceramide. Deficiency of the ASA causes...
- 10
- 504
- 0
Báo cáo khoa học: The calpain 1–a-actinin interaction Resting complex between the calcium-dependant protease and its target in cytoskeleton doc
... in the absence and in the presence of calcium, with animportant increase in the affinity in the presence of calcium.Furthermore, the cleavage of asm by calpain 1 generates a fragment of 95 kDa ... foundwithin the 10 kDa C-terminal domain of the a- actininmolecule. The inability of the 95 kDa chain (issued from the cleavage of asm by Calp1) to interact with calpain 1, couldrestrict the location of ... shows that the C-terminal domain of a- actininand each calpain subunit, 28 and 80 kDa, participates in the interaction. In particular, the autolysed calpain form(76/18) a ords a similar binding...
- 9
- 334
- 0
Báo cáo khoa học: The proximity between C-termini of dimeric vacuolar H+-pyrophosphatase determined using atomic force microscopy and a gold nanoparticle technique ppt
... electrotransblottingapparatus (Nova Blot, Amersham Pharmacia Biotech,Piscataway, NJ, USA). The blots were incubated with the rabbit polyclonal antibody raised against the MAP (Mito-gen-activated protein kinase)-conjugated ... height values of the cytosolic and luminal sides. In addition, the theoreti-cal ratio of the total amount of amino acids on the cytosolic and luminal sides was calculated as 2.31 : 1(data not ... protein concentration was calculated by a modified Bradford method with BSA as the standard [38].Measurement of proton translocationProton translocation was measured as the initial rate of flu-orescence...
- 14
- 332
- 0
Báo cáo khoa học: The molecular chaperone a-crystallin incorporated into red cell ghosts protects membrane Na/K-ATPase against glycation and oxidative stress ppt
... providedagainst Na/K-ATPase inactivation was not due to the removal of fructose by binding to a- crystallin, BSA wasresealed (in the same manner and concentration as that of a- crystallin) and incubated with ... severalpathologic states, in particular heart disease, hypertensionand cataract. Altered Na+and K+concentrations areobserved in many forms of human cataract and correlatewith increasing ... diabetes and cataract formation) wereused to test inactivation of the Na/K pump. Intracellular a- crystallin protected against the decrease in ouabain sensi-tive86Rb uptake, and therefore against...
- 7
- 291
- 0
Báo cáo Y học: The mitochondrial-lysosomal axis theory of aging Accumulation of damaged mitochondria as a result of imperfect autophagocytosis ppt
... Georgetown, Texas.25. Brunk, U.T. & Terman, A. (1999) The mitochondrial-lysosomalaxis theory of cellular aging. Understanding the Basis of Aging: the Roles of Mitochondria, Free Radicals, and Antioxidants(Cadenas, ... 774–779.48. Yoneda, M., Chomyn, A. , Martinuzzi, A. , Hurko, O. & Attardi,G. (1992) Marked replicative advantage of human mtDNA car-rying a point mutation that causes the MELAS encephalomyo-pathy. ... maintenance.Mitochondria are the main source of ROS formation, aswell as the main target for free radical attack. The accumulation of defective mitochondria within aging cellssuggests that some are not properly autophagocytosed.Aged...
- 7
- 444
- 0
Báo cáo khoa học: The )148 to )124 region of c-jun interacts with a positive regulatory factor in rat liver and enhances transcription Dipali Sharma*, Sujata Ohri and Aparna Dixit ppt
... fragment. The parameter for the degree of retardation of a linear DNA fragment boundin a complex with its specific factors reflects the molecularmass of the bound protein(s), as the molecular mass of DNA ... )124 of c-jun and stimulates transcription.Materials and methodsReagents and animalsAll chemicals were of reagent grade and were from SigmaChemical Co. unless stated otherwise. Healthy femaleinbred ... a positiveregulatory factor in rat liver and enhances transcriptionDipali Sharma*, Sujata Ohri and Aparna DixitGene Regulation Laboratory, Center for Biotechnology, Jawaharlal Nehru University,...
- 9
- 449
- 0
Từ khóa: báo cáo môn học hóa dầubáo cáo trường học văn hóa năm 2012báo cáo trường học văn hóaquảng cáo trên báo giấy hoa học tròbáo cáo giáo dục thể chất trường tiểu họcbáo cáo khoa họcNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Nghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Thiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíBT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIĐổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt nam