... function in the different cell sys- tems used. In the present study, we confirmed activa- tion of JNK and its downstream transcription factor c- JUN by JSP1, which was dependent on a functional myristoylation ... specifically activated JNK when overexpressed in human embry- onic kidney 293T cells [21]. Overexpression of a cata- lytically inactive mutant (JKAP -C8 8S) blocked tumor necrosis...
Ngày tải lên: 16/02/2014, 14:20
... anti-Bcl-2, anti-Bcl-xL and anti-b-actin serum. b-actin was used as a loading control. (G) Effect of overexpression of an Ser70-speci c mutant form of Bcl-2 (S70A) on radiation-induced Bcl-2 phosphorylation. ... the mitochondrial fraction and total cell extract were subjected to western blot analysis using anti-caspase-8, anti-Bid, anti-Bax, anti-HSP60, anti- phospho-Bcl-2, anti-Bcl-2...
Ngày tải lên: 07/03/2014, 05:20
The Project Gutenberg EBook of The Car of Destiny by C. N. Williamson and A. M. Williamson pot
... When the King came a-courting to England, came also, though not exactly in his train, another Spaniard, the Duke of Carmona, and—” “Don't,” I cut in; “I won't hear his name in connection ... and, as my childhood and early youthwere passed in England, I could use an English name without making myself ridiculous by a foreign accent. As for my brown face and black eyes, many a Cornis...
Ngày tải lên: 07/03/2014, 11:20