line in the sand

... of Pennsylvania). The telegraph wires linking stations into the nation wide network are shown by the thin black lines that have been generalized and simplified into straight -line segments. An underlying base ... billion users. The Atlas explores the new cartographic and visualization techniques being employed in the mapping of cyberspace, concentrating on the following main...

Ngày tải lên: 15/03/2014, 13:20

... spin-flips, where the flipping of a single spin alters the local fields acting on its neighbouring sites. The configuration of the spins on these sites may then no longer be locally stable, causing ... each spin interacts with all spins in the system, but with an interaction energy scaling as 1/ √ N ) will clearly not manifest this since they have in nite connectivity. More interesti...

Ngày tải lên: 01/11/2013, 08:20

... in iron-rich media showed a further increase in ROS production as deter- mined by an increase in DCFH mean fluorescence intensity (Fig. 2B, thick line) . In addition, determin- ation of acrolein ... with iron. Thin lines represent background staining with mouse Igs. (B) Histograms show background staining with no antibody (thin lines) or with rab- bit Igs (thick lines) as first step i...

Ngày tải lên: 19/02/2014, 16:20

... a protein belonging to the GTP- binding elongation factor family, which promotes the GTP- dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis and the capture ... sequence, increasing the number of basic residues of lysine, arginine and histidine, could occur. However it seemed probable that the eEF1A isoforms could act as a controlling event...

Ngày tải lên: 21/02/2014, 00:20

... newly synthesized glycoproteins has been demonstrated previously using various mammalian cell lines. Depending on the cell type, glycoproteins bearing Man9 glycans and glycoproteins bearing Man5 ... respectively, when the incubation was performed in the presence of 20 l M kifunensine after a 20 min preincuba- tion. G1M9 indicates oligomannosides con- taining one Glc, nine Man, and two...

Ngày tải lên: 16/03/2014, 16:20

... of relevant training in our Institutes and Centres and working in partnership where possible - Maintain our current investment in training schemes while modifying the existing portfolio where ... in training most of the medical oncologists practising in the UK. We will build on this to address the current deficit in clinician scientists working at the translational...

Ngày tải lên: 22/03/2014, 16:21

... confirmed, by using the human lymphoblastic T-cell line, L-MAT, as the model, that the AhR-medi- ated pathway is in no way involved in TCDD-induced apoptosis, [7,8]. Furthermore, neither TCDD-mediated apoptosis ... at the N terminus, upstream of the start codon, and SalI at the C terminus, just before the stop codon of PKCh, with pEFneo-DN PKCh being used as the template....

Ngày tải lên: 23/03/2014, 13:20

... calpain 1. We conclude that titin affords binding sites to cal- pain 1, which concentrates the protease in the regions restrained by the Z-band edge and the N1 -line as well as at the N2 -line level, ... Z -line to the M-band of the sarcomeres [23–25]. Two calpain 3-binding sites, located at the C-terminal end of titin (M -line region) and at the N2 -line region (a tr...

Ngày tải lên: 23/03/2014, 13:20

... CA, USA). The cells were maintained in RPMI-1640 containing 10% heat-inactivated bovine serum, 1 m ML -glutamine, 100 UÆml )1 penicillin and 100 lgÆml )1 streptomycin (Life Technologies, Inc. Grand Island, ... less effective than the expected effects based on tests of the compounds individually. Simply put, the point representing the dose combination lying on, below, or above the...

Ngày tải lên: 23/03/2014, 17:22

... band. The slower migrating of the two F-11 PCR bands always corresponded to the rat brain control, the faster migrating band to the N18TG2 control. In case of C the PCR product from rat brain appeared ... construct coding for a VRL-1-GFP fusion protein was prepared by cloning the open reading frame of rVRL-1 from rat brain RNA without the last codon for amino acid P761 and...

Ngày tải lên: 31/03/2014, 07:20