... protein site; LGR, leucine-rich repeat-containing G-protein-coupled receptor; LH, luteinizing hormone; LHR, luteinizing hormone receptor; LRBP, LHR mRNA binding protein; MVK, mevalonate kinase.FEBS ... (2001)Investigation of invariant serine ⁄ threonine residues in mevalonate kinase. Tests of the functional significance of a proposed substrate binding motif and a site impli-cated in human inherited ... theactive site of the enzyme is located at the interface of the N- and C-terminal domains of the monomer. Theadenosine base of ATP is bound at the base of theleft-handed b–a–b fold, where it interacts...