... HLA-A, HLA-B, and HLA-C, and three main class II molecules, HLA-DP, HLA-DQ, HLA-DR.Each arm of the MHC molecule is made up of a separate protein. In the case ofMHC I molecules, there is an α-chain ... with the protein b2 - microglobulin. An MHC II molecule is made up of an α-chain and a β-chain (for example, DP-α and DP-β), but the story becomes more complex. Each MHC mol-ecule can bind many ... haveshown in the case of HLA-DR2 and MS. (HLA-DR2 actually designates both aspecific DR-a chain allele and a DR-b chain allele.) Scientists still do not under-stand how HLA-DR2 predisposes individuals...