unsicker - cell signaling and growth factors in development

. project. Heidelberg and Göttingen September 2005 Klaus Unsicker and Kerstin Krieglstein XXIX Cell Signaling and Growth Factors in Development. Edited by K. Unsicker and K. Krieglstein Copyright  2006 WILEY-VCH. inter- and intracellular signaling in development involving growth and transcription factors. The various chapters cover general aspects of development such as e.g. stem cells, implant...

Ngày tải lên: 03/04/2014, 12:05

... HIF-1α con- tains proline residues within oxygen-dependent domains (ODDs) (30) that are hydroxy- lated by a family of prolyl hydroxylases (HIF-PH1, HIF-PH2, HIF-PH3, and HIF-PH4) (31,32). HIF-PHs ... adding additional sialic acid-containing N-linked car- bohydrates were initiated. New N-linked glycosylation consensus sequences (Asn- Xxx-Thr/Ser, where “Xxx” is any amino acid except proline)...

Ngày tải lên: 16/02/2014, 07:20

... prevalence of OAB in urologic male veterans popula- tion, the need for OAB screening, and risk factors for OAB. METHODS An IRB-approved self-administered question- naire on urinary symptoms was ... or un - treated may benefit from better detection and treat- ment initiation. The OAB-V8 questionnaire is a possi- ble effective and fast screening tool. Our study also examined...

Ngày tải lên: 25/10/2012, 11:35

... tran- scription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells. Nat Immunol 6:1054–1060 Poortinga G, Hannan KM, Snelling H, ... num- bers of crypts in the small intestine, but in long-term experiments the mice maintain a normal epithelium in the absence of c-Myc activity and without apparent compensation by N-M...

Ngày tải lên: 25/10/2013, 21:20

... of Veterinary Medicine, Brazil 3 Department of Maternal-Child Nursing and Public Health - Nursing School - UFMG, Research Group in Nutrition Interventions - GIN, Centre for Urban Health and Center ... Status and Associated Factors in Institutionalized Elderly Costa Bruna Vieira de Lima 1 , Fonseca Leorges Moraes 2 and Lopes Aline Cristine Souza 3 * 1 Nutricionista...

Ngày tải lên: 05/03/2014, 21:20

... tobacco smoke (duration and dose), including the time since quitting in ex-smokers. Similarly, the total lifetime exposure to ionising radiation for individuals in each age group in 2010 was estimated ... risk was 1.24 in women and 1.37 in men after controlling for some potential sources of bias and confounding. The excess risk increases with increasing exposure. For lung canc...

Ngày tải lên: 22/03/2014, 16:21

... by a conserved DNA-binding motif known as the Doublesex- and Mab-3-related (DM) domain. Being a noncanonical cysteine-rich DNA- binding motif, this domain has two highly intertwined finger structures ... additional expression in the germ cell lineage (Table 1). This dif- ference in cell types expressing dmrt1 might reflect spe- cies-specific differences in testicular structure and...

Ngày tải lên: 14/02/2014, 19:20

... DNA-binding and dimerization domain at their C-terminus, and a less conserved proline-rich and glutamine-rich transactiva- tion domain at their N-terminus [8–10]. Most isoforms also have a PY-motif ... alignment of AP-2a, AP-2b, AP-2c, AP-2d, and AP-2e. The proline-rich and glutamine-rich N-terminus, which is important for transactivation, is shown in yellow, and contains the PY...

Ngày tải lên: 16/02/2014, 09:20

... section and scheme of the coronal section at E14.5 in (F). (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline. Surprisingly, the ... before and after birth in mouse brains [122,124]. No HSF4 DNA-binding activity was reported in the developing mouse brain so far. How- ever, Hsf4b is expressed in the adult mouse b...

Ngày tải lên: 18/02/2014, 04:20