prognostic and predictive factors in breast cancer second edition

... surgical excision, includ- ing DCIS and invasive cancer. All patients in this study underwent clinical and radiological examination, includ- ing mammography and ultrasound. The radiological appearance ... fixed in 10% formaldehyde and embedded in paraffin. Each biopsy specimen was stained with hematoxylin and eosin. The biopsy slides were reviewed by experienced pathologists and diagnosed according ... clinico-pathological and radiological findings of ADH diagnosed by CNB were assessed to clar- ify predictors that could be useful in distinguishing between ADH and cancer containing DCIS. ADH is...

Ngày tải lên: 09/08/2014, 04:21

... apoptosis-inducing efficacy in breast cancers. Second, additional approaches to achieving a “genuine” breast cancer targeting in drug delivery or gene expression facilitate reducing a systemic ... organs, including mammary glands, in female goats and sheep (Glascock and Hoekstra 1959). This finding was a crucial observation to understand the role of estrogens in processes involving target ... activity in treatment of breast cancers in a phase I trial, and conferred therapeutic benefits in combination with chemotherapy in triple-negative breast cancers without an increase in normal...

Ngày tải lên: 23/03/2014, 17:20

... fusion gene encoding the chimeric protein of caspase-8 and the ligand-binding domain (LBD) of ERα and introduced the gene into breast cancer cell lines (Zhao et al, 2011). Upon administration of ... apoptosis-inducing efficacy in breast cancers. Second, additional approaches to achieving a “genuine” breast cancer targeting in drug delivery or gene expression facilitate reducing a systemic ... TARGETING NEW PATHWAYS AND CELL DEATH IN BREAST CANCER Edited by Rebecca L. Aft Targeted Apoptosis in Breast Cancer Immunotherapy 27 clinical breast adenocarcinomas (Vinothini...

Ngày tải lên: 27/06/2014, 11:20

Ngày tải lên: 10/08/2014, 10:21

... example, this edition includes new data on tamoxifen and raloxifene in breast cancer prevention, MRI screening in breast cancer, and the integration of bevacizumab and trastuzumab into current ... recur- rent breast cancer with screening for second primary tumors in selected breast cancer survivors. E PIDEMIOLOGY Excluding cancers of the skin, breast cancer is the most common cancer among ... services, including breast and ovarian cancer genetic counseling and testing, risk reduction counseling, chemopreven- tion, and screening. Diagnostic services for individuals with undiagnosed breast...

Ngày tải lên: 25/12/2013, 21:15

Ngày tải lên: 09/08/2014, 07:21

... ASSURANCE IN BREAST CANCER SCREENING 31 H1 20-09-2005 20:53 Pagina 31 European guidelines for quality assurance in breast cancer screening and diagnosis Fourth edition In presenting this fourth edition ... continuing advances in technical and professional knowledge. Certain principles remain just as important in diagnosis as they are in screening. Training, multi- disciplinary teamwork, monitoring ... European guidelines for quality assurance in breast cancer screening and diagnosis Fourth edition TABLE OF CONTENTS XV 88 Data collection and monitoring in breast cancer screening and care 335 8.1...

Ngày tải lên: 15/03/2014, 00:20

... hormones in the UK in 2010 S42 DM Parkin 11. Cancers attributable to infection in the UK in 2010 S49 DM Parkin 12. Cancers in 2010 attributable to ionising radiation exposure in the UK S57 DM Parkin and ... (2003) European Prospective Investigation into Cancer and Nutrition. Dietary fibre in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): ... Parkin 15. Cancers attributable to reproductive factors in the UK in 2010 S73 DM Parkin 16. The fraction of cancer attributable to lifestyle and environmental factors in the UK in 2010: Summary and...

Ngày tải lên: 22/03/2014, 16:21

... increase. We observed an increase in HIF-1a protein, and thus were confident that the cells were being maintained in a low-oxygen environment and were responsive to low oxygen. There is also increasing ... the data in Fig. 2 support the involvement of a TRAIL-dependent process in mediating hypoxia- induced changes in BRCA1 localization. TRAIL, but not hypoxia, induces apoptosis in breast cancer cells As ... proteins involved in various cellular processes, including inhibi- tion of apoptosis. Hypoxia has been reported to inhibit apoptosis induced by tumor necrosis factor-related apoptosis- inducing...

Ngày tải lên: 30/03/2014, 03:20

... behavioural changes linked with minimising lifestyle risk factors for recurrence of cancer [9], and improving psychosocial factors during and after cancer treatments [10]. Cancer patients as ... intervention for enhancing QOL in cancer survivors. Research has provided preliminary evidence for the safety, feasibility, and efficacy of exercise training in breast cancer survivors. The aim ... other diseases, and extending survival in cancer survivors. Preliminary research suggests that exercise may be an effective intervention for enhancing QOL in cancer survivors and that this effect...

Ngày tải lên: 08/08/2014, 16:23

... Griffiths K: A prognostic index in primary breast cancer. Br J Cancer 1982, 45:361-366. 11. Duffy SW, Taba’r L, Fagerberg G, Gad A, South MC, Day NE: Breast screening, prognostic factors and survival–results ... IO, Hinton CP, Blamey RW, Haybittle JL: Confirmation of a prognostic index in primary breast cancer. Br J Cancer 1987, 56:489-492. 14. Lonn U, Lonn S, Nilsson B, Stenkvist B: Breast cancer: prognostic significance of ... the extent of tumor invasion, LN metastasis, distant metastasis and TNM staging thus enveloping all aspects of breast cancer. Introduction Breast cancer is a disease affecting millions of women...

Ngày tải lên: 09/08/2014, 01:24

... its design and coordination and helped to draft the manuscript. All authors read and approved the final manuscript. Competing interests The authors declare that they have no competing interests. Received: ... penetrating into t he gastric lumen and peri- colic soft tissue. Other gastrointestinal tumors may also contain calcifi- cation. At least three types of calcification have been reported in gastric cancer: ... Gastrointestinal stromal tumors. Virchows Arch 2010, 456(2):111-127. 3. Miettinen M, Lasota J: Gastrointestinal stromal tumors–definition, clinical, histological, immunohistochemical, and molecular...

Ngày tải lên: 09/08/2014, 01:24

... survival in invasive breast cancers [24]. In conclusion, we found that the incidence of sent inel lymph node metastasis in cases of pure DCIS was 0.39%. This incidence was lower than that in IDC-pre- dominant ... and the outcome of breast cancer. N Engl J Med 2009, 361:653-663. doi:10.1186/1477-7819-8-6 Cite this article as: Tada et al.: Ductal carcinoma in situ and sentinel lymph node metastasis in breast ... S, Vitelli CE, Rome Breast Cancer Study Group: Sentinel lymph node biopsy in women with pT1a or “microinvasive” breast cancer. Breast 2008, 17:395-400. 16. Zavagno G, Belardinelli V, Marconato...

Ngày tải lên: 09/08/2014, 03:21

... ML: Influence of a diet very high in vegetables, fruit, and fiber and low in fat on prognosis following treatment for breast cancer: the Women's Healthy Eating and Living (WHEL) randomized ... contraceptives and prognosis in breast cancer: effects of duration, latency, recency, age at first use and relation to parity and body mass index in young women with breast cancer. Eur J Cancer 1994, ... rate in 276 patients included in Danish Breast Cancer Cooperative Group (DBCG) 82b and 82c trials was found to be 27% [10]. In the present study, most recurrence of breast cancer occurred within...

Ngày tải lên: 09/08/2014, 03:21

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Ngày tải lên: 09/08/2014, 09:20

Ngày tải lên: 09/08/2014, 09:20