Báo cáo Y học: Substrate speciﬁcity of human kallikrein 2 (h

Báo cáo Y học: Substrate speciﬁcity of human kallikrein 2 (hK2) as determined by phage display technology docx

... Substrate specificity of human kallikrein 2 (hK2) as determined by phage display technology Sylvain M. Cloutier 1 , Jair Ribeiro Chagas 2 , Jean-Pierre Mach 3 , Christian M. Gygi 1 , Hans-Jurg ... selected by substrate phage display with hK2. Ó FEBS 20 02 Substrate specificity of kallikrein hK2 (Eur. J. Biochem. 26 9) 27 51 modification in the Km...

Ngày tải lên : 31/03/2014, 23:20

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Tài liệu Báo cáo khoa học: Substrate speciﬁcity of the pseudouridine synthase RluD in Escherichia coli doc

... TY-loop [20 ,26 ]. A second cocrystal structure of pseudouridine synthase and its substrate was recently determined for RluA and the anticodon stem loop (ASL) of tRNA [21 ]. This enzyme gains speciﬁcity ... pattern in ribosome assembly precursor particles of 23 S rRNA has shown that the pseudouridines in H69 are formed by RluD during late assembly. RluD can function in ribosome...

Ngày tải lên : 18/02/2014, 16:20

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Báo cáo khoa học: Substrate speciﬁcity of vaccinia virus thymidylate kinase docx

... 9-R- (2- phosphonylmethoxypropyl)adenine; TMP, thymidylate; U, enzyme activity unit (1 lmole substrate transformed per minute); VVTMP kinase, vaccinia virus thymidylate kinase. 625 4 FEBS Journal 27 2 (20 05) 625 4– 626 5 ... Mg 2+ , yielding thymidine 5¢-diphos- phate (dTDP) and ADP. The vaccinia virus thymidylate kinase gene has been cloned and identiﬁed by homology with yeast thy...

Ngày tải lên : 16/03/2014, 14:20

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Báo cáo khoa học: Substrate speciﬁcity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7 Identiﬁcation of a critical aromatic amino acid residue at position 33 doc

... four days in the case of UGT2B4 and UGT2B4F3 3Y and for one week in the case of UGT2B 4Y3 3L. Substrate speciﬁcity in UGT2B4 and UGT2B7 L. Barre et al. 125 8 FEBS Journal 27 4 (20 07) 125 6– 126 4 ª 20 07 ... the substrate speci- ﬁcity of the mutant UGT2B4F3 3Y, in which phenylalanine was replaced by tyrosine, as found at position 33 of UGT2B7, was similar to wild-type U...

Ngày tải lên : 23/03/2014, 09:21

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Tài liệu Báo cáo khoa học: Substrate speciﬁcity and inhibition of brassinin hydrolases, detoxifying enzymes from the plant pathogens Leptosphaeria maculans and Alternaria brassicicola ppt

... BHLmL2. By contrast, the rates of hydrolysis of methyl tryptopholdithiocarbonate (16) and methyl tryptaminedithiocarbamate (9) catalysed by BHLmL2 were substantially higher than those catalysed by ... authors. Brassinin hydrolases M. S. C. Pedras et al. 7 428 FEBS Journal 27 6 (20 09) 74 12 7 428 ª 20 09 The Authors Journal compilation ª 20 09 FEBS Substrate speciﬁcity and in...

Ngày tải lên : 18/02/2014, 14:20

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Báo cáo khoa học: Substrate speciﬁcity and transport mode of the proton-dependent amino acid transporter mPAT2 potx

... accepted 24 June 20 04) Eur. J. Biochem. 27 1, 3340–3347 (20 04) Ó FEBS 20 04 doi:10.1111/j.14 32- 1033 .20 04.0 426 8.x physiological role of the PAT2 transporter is c urrently not known. We previously reported ... reference substrate glycine. This is striking in the case Fig. 1. Substrate speciﬁcity of mPAT2. (A,B) Representative current traces of oocytes expressing mP AT2 i...

Ngày tải lên : 07/03/2014, 16:20

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Báo cáo khoa học: Substrate speciﬁcity and excision kinetics of natural polymorphic variants and phosphomimetic mutants of human 8-oxoguanine-DNA glycosylase pot

... of stimulation of the DNA glycosylase activity of hOGG1 by the major human AP endonucle- ase: bypass of the AP lyase activity step. Nucleic Acids Res 29 , 128 5– 129 2. 20 Saitoh T, Shinmura K, Yamaguchi ... Substrate speciﬁcity and reaction mechanism of murine 8-oxoguanine-DNA glycosylase. J Biol Chem 27 5, 28 607 28 617. 24 Sidorenko VS, Nevinsky GA & Zharkov DO (...

Ngày tải lên : 23/03/2014, 05:22

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Báo cáo khoa học: Site speciﬁcity of yeast histone acetyltransferase B complex in vivo pot

... acetylation by Gcn5p of histones H3 and H4 at speciﬁc lysines. Nature 383, 26 9 27 2. Yeast histone acetyltransferase B complex A. Poveda and R. Sendra 21 34 FEBS Journal 27 5 (20 08) 21 22 21 36 ª 20 08 ... thr ) tyr ) hhf1::HIS3 hhf2::LEU2 pPK 626 (URA3-HHF2) M. Grunstein LDY105 MATa ade2-101 arg4-1 his3 -20 1 leu2-3,1 12 lys2-801 trp1-901 ura3- 52 thr ) tyr ) hhf1::HIS3 hhf2::LE...

Ngày tải lên : 07/03/2014, 05:20

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Báo cáo khoa học: Aglycone speciﬁcity of Escherichia coli a-xylosidase investigated by transxylosylation ppt

... a-xylosidase (YicI), which belongs to glycoside hydrolase family 31, was characterized by examining the enzyme’s transxylosylation-catalyzing property. Acceptor speciﬁcity and regioselectivity ... aglycone-binding site in both hydrolysis and transglycosylation. Transglycosylation is useful as a probe for studying the speciﬁcity of hydrolytic activity, thus avoiding the synthesis...

Ngày tải lên : 23/03/2014, 07:20

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Báo cáo khoa học: The speciﬁcity of alcohol dehydrogenase with cis-retinoids Activity with 11-cis-retinol and localization in retina docx

... x-hydroxyfatty acids and cytotoxic aldehydes as physiological substrates, and H 2 -receptor antagonists as phar- macological inhibitors, of human class IV alcohol dehydrogenase. FEBS Lett. 426 , ... 1355 all-trans-retinol 9 ± 2 20 ± 2 222 0 ± 540 9-cis-retinol 29 ± 3 100 ± 5 3450 ± 395 11-cis-retinol 24 ± 4 40 ± 2 1670 ± 29 0 all-trans-retinal 17 ± 3 31 ± 2 1 825 ± 345 9-...

Ngày tải lên : 23/03/2014, 12:20

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