Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
Báo cáo Y học: Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt ppt
... 791 Conformationally constrained human calcitonin (hCt) analogues reveal a critical role of sequence 17–21 for the oligomerization state and bioactivity of hCt Athanasios Kazantzis 1 , Michaela Waldner 1 , ... 3, respectively, and als o a linear control peptide for 1a , analogue 1b. Conformational analyses by CD: studies of hCt and the...
Ngày tải lên: 31/03/2014, 21:21
Báo cáo y học: "Electronic patient record use during ward rounds: a qualitative study of interaction between medical staff"
... types of form (the observation chart, the drug chart, and the plan of the day) and a folder or binder for mis- cellaneous and patient-specific forms and papers. The obser- vation chart was A3 -size ... allow focus on the conversation rather than the data, as described above, and the use of paper to provide relevant data – are not surprising in that they add...
Ngày tải lên: 25/10/2012, 10:31
Báo cáo y học: "Strict glycaemic control in patients hospitalised in a mixed medical and surgical intensive care unit: a randomised clinical trial"
... interpreta- tion, and drafting of the manuscript, NS, MB, JT, JV, JV, CA, PA, EV, JCH, AY, WP and CC participated in the study design, data acquisition and drafting of the manuscript. All authors read and approved ... uri- nary infections, catheter-related infections and primary bacter- aemias); ICU length of stay; days of mechanical ventilation and incidence of se...
Ngày tải lên: 25/10/2012, 10:35
Tài liệu Báo cáo khoa học: Trophoblast-like human choriocarcinoma cells serve as a suitable in vitro model for selective cholesteryl ester uptake from high density lipoproteins pdf
... Histology and Embryology, 3 Clinic of Obstetrics and Gynecology, Karl-Franzens University Graz, Austria As human choriocarcinoma cells display many of the biochemical and morphological characteristics ... represents the epithelial layer separating the maternal and fetal circulation [18]. In the human placenta chorionic villi, a layer of syncytiotropho- blasts lies...
Ngày tải lên: 20/02/2014, 23:20
Báo cáo Y học: Double-stranded RNA-activated protein kinase interacts with apoptosis signal-regulating kinase 1 Implications for apoptosis signaling pathways docx
... in the figure legend. The phosphorylation reaction was resolved by SDS/PAGE and visualized by autoradio- graphy. Autoradiogram was scanned and densitometric analysis was performed with Kodak DIGITAL ... not play only a structural role but rather modulates a signaling pathway of ASK1. Therefore the binding of PKR to ASK1 might cause a conforma- tional change in ASK1 for...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo Y học: Disul®de bond formation through Cys186 facilitates functionally relevant dimerization of trimeric hyaluronan-binding protein 1 (HABP1)/p32/gC1qR docx
... BSA. Therefore, the dissociation constant for the hyaluronan±HABP1 i nteraction was calculated b y Scatchard plot analysis from the data in Fig. 5A, taking the average molecular mass of hyaluronan ... biotinylated hyaluronan, biotinylated D -mannosylated BSA, and g C1q. The hexamer generated by thiol-group oxidation o f native HABP1 had greater af®nity for its ligand than...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo khoa học: Substrate recognition by three family 13 yeast a-glucosidases Evaluation of deoxygenated and conformationally biased isomaltosides pptx
... using the relevant deoxygenated D -glucose as standard. The a- glucosidase catalyzed hydro- lysis was initiated by a ddition of 0.1±91 U enzyme. The limited amounts of deoxygenated analogs available ... smallest for t he 6¢-deoxy ana log and largest for the 2¢-deoxy analog, while intermediary losses in activity for 3¢ -and4 ¢-deoxy analogs did show small variations amon...
Ngày tải lên: 23/03/2014, 21:21
Báo cáo Y học: GNA33 from Neisseria meningitidis serogroup B encodes a membrane-bound lytic transglycosylase (MltA) pdf
... products [10]. By virtue of their ability to cleave the polysaccharide backbone of the peptidoglycan layer, lytic transglycosylases are thought to play a role in synthesis and degradation of the murein sacculus. ... with each other. Lytic transglycosylases are a unique class of lysozyme-like enzymes that catalyze cleavage of the b-1,4-glycosidic bond between N-acetyl...
Ngày tải lên: 31/03/2014, 23:20
Báo cáo khoa học: Adeno-associated virus gene transfer in Morquio A disease – effect of promoters and sulfatase-modifying factor 1 pot
... keratan sulfate and chondroitin 6-sul- fate, mainly in bone and cornea [1]. Clinical manifestations vary from severe to attenuated forms characterized by systemic skeletal dysplasia, laxity of joints, ... PH, Parthasarathy S, Isaacs J, Vijay S, Kieran J, Powell SK, McClelland A & Wright JF (2003) Quantification of adeno-associated virus par- ticles and empty capsids by optical...
Ngày tải lên: 29/03/2014, 21:20
Báo cáo y học: "Expression of Human Globular Adiponectin-Glucagon-Like Peptide-1 Analog Fusion Protein and Its Assay of Glucose-Lowering Effect In Vivo"
... sonicated and centrifuged to separate the supernatant and inclusion body. Part of the production was applied to 12% SDS–PAGE analysis and Western blot analysis. (A) SDS-PAGE analysis: Most of the ... circumvent the rapid inactivation and renal clearance of GLP-1 is therefore an important step toward applying them therapeutically [5, 6]. Type 2 diabetes is characteri...
Ngày tải lên: 25/10/2012, 11:10