Báo cáo khoa học: TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase–AKT–JNK pathway pptx
Báo cáo khoa học: TRAF6 and C-SRC induce synergistic AP-1 activation via PI3-kinase–AKT–JNK pathway pptx
... expression.
TRAF6 and c-Src induce AP-1 activation independently
Then, in order to investigate the mutual dependency of
TRAF6 and c-Src in AP-1 activation, we cotransfected
c-Src KD with TRAF6 and determined ... coexpression of TRAF6 and c-Src (Fig. 4D). In
contrast, levels of c-Jun mRNA was changed little by the
overexpression of TRAF6 and/ or c-Src. Thus...
Báo cáo khoa học: Isolation and characterization of a D-cysteine desulfhydrase protein from Arabidopsis thaliana pptx
... from
transfer into pots, and the parts above ground were cut
every week. The oldest leaves were comparable to the S3
stage as defined [39].
The influence of light and darkness on expression and
activity were ... the proteins and the mix-
ture was used for two subsequent immunizations of two
rabbits according to standard procedures. In western blot
trials using d-CDes recombinant protein...
Báo cáo khoa học: Cloning and functional analysis of 5¢-upstream region of the Pokemon gene pptx
... sequences (254 and 106 bp) between the NEG-
U and NEG-D elements. The distance between the NEG-U and
NEG-D elements was 253 and 106 bp in D-254 and D-106, respec-
tively. The right-hand panel shows ... and BETA2⁄ E47
was not mediated via SREs but via the E-boxes.
Reducing the distance between the two E-boxes abol-
ished synergistic activation. Therefore, the synergistic
a...
Tài liệu Báo cáo khoa học: Applications and trends in systems biology in biochemistry docx
... acid,
arginine
catabolism
to NO and
polyamines
NG, aorta
endothelial
cells
Low affinity transporter and arginase
share the control of the fluxes
through the pathways involving
arginine as a precurser of nitric
oxide and polyamines
ODE ... Carbohydrate,
glycolysis
Lactococcus
lactis
Modeling Pi explicitly and regulation
of pyruvate kinase (by Pi and FBP),
PFK (by PEP) and GAPDH (by
N...
Tài liệu Báo cáo khoa học: Structure and function of active chromatin and DNase I hypersensitive sites pdf
... of
AP-1 via cooperative binding, and creates an accessi-
ble environment that also enables Sp1 and Runx1
binding [85,86,233]. Both NFAT and AP-1 have the
potential to recruit the HATs CBP and ... factors [86,233]. In response to induction of
NFAT and AP-1, these two nucleosomes are evicted
and replaced by NFAT ⁄ AP-1 ⁄ Sp1 and NFAT⁄ AP-1 ⁄
RUNX1 enhanceosome-like comp...
Tài liệu Báo cáo khoa học: miRNAs and regulation of cell signaling pptx
... (C) EcR signaling pathway, (D)
Hippo signaling pathway, (E) TGF-b signaling
pathway, (F) Hh signaling pathway, and (G)
Wnt signaling pathway.
miRNAs and cell signaling A. Ichimura et al.
1612 FEBS ... tumors and cell lines, miR-17-
5p and miR-20a are induced in a manner that depends
on cyclin D1 and repress the expression of cyclin D1.
Hence, miR-17-5p ⁄ 20a and cyclin D1 fo...
Tài liệu Báo cáo khoa học: MicroRNAs and epigenetics doc
... oncogenesis and
cancer metastasis, including MYC, CDK4, CDK6 ,
E2F3, CREB and MET [33,37,41]. Ectopic expression
of miR-34 species induces cell-cycle arrest and apopto-
sis and suppresses cell growth and ... [20]. Next, one
strand (the passenger strand) of the miRNA is
removed from the RLC, whereas the other strand (the
guide strand) remains in the complex to form a
mature RNA-induc...
Tài liệu Báo cáo khoa học: MicroRNAs and cardiovascular diseases ppt
... [78,79]. I ⁄ R in the heart induced
miR-21 in cardiac fibroblasts in the infracted region.
Thus, I ⁄ R-induced miR-21 limits PTEN function and
causes activation of the Akt pathway and increa-
sed matrix ... hypertrophy-associated calmodulin, MEF2a and
GATA4, and attenuates calcium-dependent signaling
through the calcineurin-NFAT pathway [49]. miR-133
inhibits hypertrophy through...
Tài liệu Báo cáo khoa học: Functional and structural analyses of N-acylsulfonamidelinked dinucleoside inhibitors of RNase A ppt
... binding and cleav-
age by ribonuclease A and variants at Lys7, Arg10, and
Lys66. Biochemistry 37, 12121–12132.
31 Anderson DG, Hammes GG & Walz FG Jr (1968)
Binding of phosphate ligands to ... where I
i
(h) and I(h) are the ith and the mean
measurements of the intensity of reflection h, respectively. R
cryst
= R
h
|F
o
) F
c
| ⁄ R
h
F
o
, where F
o
and F
c
are the observed and...
Tài liệu Báo cáo khoa học: Active and regulatory sites of cytosolic 5¢-nucleotidase doc
... mediate
interaction in the first activation site (R144, N154, I152) and three in the
second (F127, M436 and H428), and found that Ap
4
A and ADP interact
with the same site, but the sites for ATP and BPG remain ... cN-II, cN-III, cN-IA and cN-IB, and
both cytosolic and mitochondrial 5¢(3¢)-deoxyribonu-
cleotidases [5]. Even though all soluble 5 ¢-nucleotidases
share the same...
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