Báo cáo khoa học: Identiﬁcation and characterization of nove

Báo cáo khoa học: Identiﬁcation and characterization of novel salivary thrombin inhibitors from the ixodidae tick, Haemaphysalis longicornis doc

... Identiﬁcation and characterization of novel salivary thrombin inhibitors from the ixodidae tick, Haemaphysalis longicornis Shiroh Iwanaga 1 , Masakazu ... inhibition of thrombin by antithrombin III [13] and heparin cofactor II [14]. Furthermore, both exosites areinvolvedintherecognitionoffactorVandfactorVIII by thrombin [15]. The salivary glands of bl...

Ngày tải lên : 31/03/2014, 01:20

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Báo cáo khoa học: Identiﬁcation and characterization of novel PKA holoenzymes in human T lymphocytes pdf

... RIa,RIb, RIIa and RIIb, and three different genes encode three C isoforms, Ca,Cb and PRKX [1]. The Ca and Cb isoforms are closely related in protein sequence while the PRKX is more different from Ca and ... antibody-immobilized Cb2 isoform would remain in the pellet in the absence of 8-CPT-cAMP while they would be released to the supernatant in the presence of 8-CP...

Ngày tải lên : 16/03/2014, 18:20

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Tài liệu Báo cáo khoa học: Identiﬁcation and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebraﬁsh, Danio rerio docx

... expression of T-bet has been seen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung tissue of mouse and spleen and thymus of human and mouse ... CD4 + CD25 + Foxp3 + T reg or whether they induce the production of these cytokines from another population of cells [20]. To date, our knowledge about the differen...

Ngày tải lên : 16/02/2014, 09:20

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Tài liệu Báo cáo khoa học: Identiﬁcation and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni pdf

... reporter); the duration of the development of blue color in the LacZ ﬁlter-lift assay (activation of LacZ reporter); and the b-gal units calculated from the liquid LacZ assay (activation of LacZ ... of cellular media- tors called receptor-regulated Smads (R-Smads). The R-Smads of the TGF b–activin pathway include Smad2 and Smad3. The R-Smads of the BMP pa...

Ngày tải lên : 18/02/2014, 16:20

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Báo cáo khoa học: Identiﬁcation and characterization of a nuclear receptor subfamily I member in the Platyhelminth Schistosoma mansoni (SmNR1) pot

... acids at the 5¢ end of the DBD, the DBD and the 40 amino acids at the 3¢ end of the DBD of SmNR1 (Ile247-Ser372) and SmRXR1 (Glu251-Asn376) were tested in vitro. Lanes 1, 5, 9, 13, 17, 21, 25 and ... most NRs, and the length of the hinge in SmNR1 thus can be estimated to be 140 amino acids. The role of the large hinge in schistosome NRs remains unknown....

Ngày tải lên : 07/03/2014, 11:20

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Báo cáo khoa học: Identiﬁcation and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf

... periods of time (Fig. 3). As shown, the addition of stressors to the cul- tures inhibits growth without killing the cells. The hybridizing band in the northern analysis showed the expected size of ... shown that the protein can shift from a monomer to a multi- meric form depending on the protein concentration and the temperature. On the basis of the data repo...

Ngày tải lên : 07/03/2014, 12:20

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Báo cáo khoa học: Identiﬁcation and characterization of B¢¢-subunits of protein phosphatase 2 A in Xenopus laevis oocytes and adult tissues Evidence for an independent N-terminal splice variant of PR130 and an extended human PR48 protein pot

... analysis of the structure of the latter made it possible to improve the current knowledge of the mammalian PR48 cDNA. To extend these ﬁndings, the genomic structures of the human PR130 and PR48 ... different classes of cDNAs were isolated and analysed. The ﬁrst is the Xenopus orthologue of PR130, the second proved to be a novel splice variant and the th...

Ngày tải lên : 08/03/2014, 08:20

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Báo cáo khoa học: Identiﬁcation and characterization of plasma kallikrein–kinin system inhibitors from salivary glands of the blood-sucking insect Triatoma infestans pptx

... Matsuoka H, Ando K, Watanabe T, Suzuki K et al. (1996) Puriﬁcation, characterization and cDNA cloning of a novel anticoagulant of the intrinsic pathway, (prolixin-S) from salivary glands of the blood sucking ... activation of FXII and PK and subsequent bradykinin generation. The triafestins exert this activity by binding to both FXII and HK in the presence o...

Ngày tải lên : 16/03/2014, 05:20

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Báo cáo khoa học: Identiﬁcation and characterization of oxidized human serum albumin A slight structural change impairs its ligand-binding and antioxidant functions pptx

... with the excep- tion of the other peaks in the cysteinylated HSA sam- ple solution. The difference of relative molecular mass of the peak d and the peak g (162.2 Da) and that of peak c and peak ... as an endogenous ligand which binds to site II, and of cefazolin (site I-ligand) and verapamil (site I and II-ligand) as exogenous ligands. All these ligands are...

Ngày tải lên : 16/03/2014, 13:20

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Báo cáo khoa học: Identiﬁcation and characterization of four novel peptide motifs that recognize distinct regions of the transcription factor CP2 doc

... know whether PKC-d and CKII-a can also alter the effect of YY1 on CP2. We also demonstrated that, unlike the HXPR and ASR motifs, PHL and PXHXH motifs bind to the N- and C-terminal parts of the Elf-1 ... staining and anti-HA blotting of the input materials ascertain the equivalent amounts of extracts and peptides between each pull-down samples being employed. A...

Ngày tải lên : 16/03/2014, 18:20

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