Báo cáo khoa học: Serpins 2005 – fun between theb-sheets Meeting report based upon presentations made at the 4th Interna-tional Symposium on Serpin Structure, Function and Biology (Cairns, Australia) doc

... REVIEW ARTICLE Serpins 2005 – fun between the b-sheets Meeting report based upon presentations made at the 4th Interna- tional Symposium on Serpin Structure, Function and Biology (Cairns, Australia) James ... polymerization and con- formational diseases such as the human serpinopathies. This review reports on recent major discoveries i...

Ngày tải lên: 30/03/2014, 20:20

... resolution Meeting report based upon presentations at the 10th International Global BioMillennium 2006 symposium on molecular cell biology (Tbilisi, Georgia) Hermona Soreq 1 and Alik Honigman 2 1 ... trans-phosphorylation and subsequent functional activation of ZIPk. DAP5 is a translation initiation factor that directs internal ribo- some entry site (IRES)-dependent tr...

Ngày tải lên: 19/02/2014, 02:20

... TatABC mutations under conditions of high translocation activity. Among numerous TatA or TatB mutations tested, TatA F39A alone blocked translocation, and only substitutions of P48 and F94 in TatC blocked ... for the first time that combinations of TatA ⁄ TatB mutations can have far more dramatic effects than the individual mutations. Mutations in the transmembrane spans of TatA and...

Ngày tải lên: 19/02/2014, 17:20

... modification of NarJ conformation during complex formation with the NarG( 1–1 5) peptide. Isothermal titration calo- rimetry and BIAcore experiments support a model whereby the protonated state of the ... affected upon peptide binding (Fig. 4C). The decrease in some of the free state resonances and the appearance of new resonances upon complex formation indicated a slow e...

Ngày tải lên: 16/02/2014, 14:20

... ÔCATATGÕ, ÔCATA TGCTÕ, ÔCATATGCTCÕ and the 21 nucleotide fragment at the 3¢ terminal. We found that –RNA1 was the m ost efficient competitor, then –RNA4, a nd –RN A5 w as the poorest among these ... respectively, the RNA templates con- taining the m inus-strand 3¢ UTRwithdeletionofÔCÕ, ÔATATGÕ, ÔATATGCTÕ, ÔATATGCTCÕ and the 21 nucleotide fragment at the 3 ¢ terminal. (B...

Ngày tải lên: 19/02/2014, 16:20

... of information is available about the structure and the functioning of the reg- ulatory regions that determine the expression pattern of Abd-B, it is still not clear how these regulatory regions can ... relative to the boundary, of the con- struct. However, when the combination of the PTS and the bound- ary is placed 3¢ to one of the reporter genes, the enhancer is t...

Ngày tải lên: 20/02/2014, 01:20

... commands, version number/identification, info on last-changed pages etc.; most of this can be used to improve the overall translation quality. On the other hand, part of it is somewhat confusing ... translation scheme (in the sense we do not use any intermediate pilot language), but with many simplifications due to the close relationship between Czech and Russian, so...

Ngày tải lên: 22/02/2014, 10:20

... tuples from text. One is detecting whether or not a given pair of NEs are semantically related (relation detec- tion), and the other is determining the relation label (relation characterization). In this ... in Section 3 and conclude the paper in Section 4. 2 Relation Detection The proposed method employs contextual features based on centering theory (Grosz et al., 1983) as we...

Ngày tải lên: 17/03/2014, 04:20

... relation between them; the task is to choose the relation. The Timebank Corpus uses relations that are based on Allen’s set of thir- 174 teen (Allen, 1984). Six of the relations are inverses of the ... results on this enlarged dataset. We could not duplicate their reported per- formance on this enlarged data, and instead focus on performing well on the Timebank dat...

Ngày tải lên: 23/03/2014, 18:20

... was the case for purified standard proteins. This degradation is based upon protein instability, even at a low temperature. In the case of degradation, the fusion protein and the major degradation ... incubation conditions, (His) 6 –NrpRII and interacting MBP–NrpRI were eluted in the presence of the respective 2-oxoglutarate concentration (0, 2 or 10 mm 2-oxoglutarate)....

Ngày tải lên: 29/03/2014, 21:20