Báo cáo khoa học: Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose ppt
Báo cáo khoa học: Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose ppt
... 2 thatdelineate the carbohydrate-binding cavity of the lectin protomer). A closer examination of the structure of the binding sites indicates that specificity of the Mora-ceae lectins is primarily ... Structural analysis of the jacalin-related lectin MornigaM from the black mulberry (Morus nigra) in complex with mannose Anja Rabijns1, Annick Barre2, ... protomers of the tetramer. This loop forms the roof of the sugar binding pocket of MornigaM and hence its different orientation might be relatedto the observed lack of binding of mannose in the ATable...
- 8
- 371
- 0
Báo cáo khoa học: Structural analysis of the N-glycans of the major cysteine proteinase of Trypanosoma cruzi Identification of sulfated high-mannose type oligosaccharides doc
... (oligosaccharides from C-terminal domain or from the whole protein) and usingdifferent equipment. Therefore, the retention of watercan be explained taking into account its strong interac-tion with the negative ... structures of the N-linked oligosaccharides present in cruzipain.HPAEC analysis of the total neutral oligosaccharidefraction obtained from the C-terminal domainshowed a mixture of different types of ... for the first time, the pres-ence of sulfate in the N-linked oligosaccharides of cruzipain. This structural feature was confirmed in the unique N-glycosidic site present in the C-terminaldomain;...
- 13
- 536
- 0
Báo cáo khoa học: Functional analysis of a murine monoclonal antibody against the repetitive region of the fibronectin-binding adhesins fibronectin-binding protein A and fibronectin-binding protein B from Staphylococcus aureus pot
... these, there is the possibility that, through the effect of the proximities of the antibody-binding andFn-binding sites, the interaction of the repeat with Fnmay be sterically hindered in the ... fibronectin. The C-terminal domain of fibronectin-binding protein A is organized into 11tandem repeats, six of which bind the ligand with high affinity; other sitesbind more weakly. Fibronectin-binding ... to the N-terminal segment and the fibronectin-binding siteto the C-terminal segment of the repeat. The distinct localization of the 15E11 epitope and the fibronectin-binding site suggests that the...
- 16
- 560
- 0
Báo cáo khoa học: Structural analysis of lipopolysaccharides from Haemophilus influenzae serotype f Structural diversity observed in three strains ppt
... most of the steps in the biosynthesis of the oligosaccharide portion of the LPSmolecules. The genes lpsA, lic2A and lgtC encodeglycosyltransferase enzymes involved in the addition of the globoside ... representativeofthediversitywithinthetypefcluster.Previous studies of LPS from H. in uenzae haveresulted in a structural model consisting of a conservedFig. 4. Selected region of the two-dimensionalNOESY ... b-D-Glcp) in all strains investigated. Thisglucose can provide a point for further chain extension.There is no chain extension from HepII in the typed-derived strain Rd [2], however, in three...
- 15
- 374
- 0
Tài liệu Báo cáo khoa học: Crystal structure of thiamindiphosphate-dependent indolepyruvate decarboxylase from Enterobacter cloacae, an enzyme involved in the biosynthesis of the plant hormone indole-3-acetic acid doc
... molecules of the cofactors ThDP and Mg2+. The ThDP binding sites arelocated in narrow clefts at the interfaces formed by the PYRdomains from one subunit and the PP domains of the othersubunit within ... orientation of the aminopyrimidine ring, areconserved in all ThDP-dependent enzymes. One of these, the hydrogen bond between the N1¢ atom of the pyrimidinering of ThDP and the side chain of an invariant ... enzymes.Substrate binding site and catalytic residues The active site cavity in IPDC extends from the thiazoliumring of the cofactor to the surface of the protein. The entrance of the active site...
- 10
- 557
- 0
Báo cáo khoa học: Structural diversity of angiotensin-converting enzyme Insights from structure–activity comparisons of two Drosophila enzymes docx
... in ANCE and ACER,respectively, which in our models are pointing away from the inhibitor so that the change in the size of the side chain may have minimal effect on binding. Val956 of C-domain ... studies con-firm many of the predictions regarding the identity of the active-site residues and, in the case of tACE, iden-tify other side chains involved in the binding of Cl–attwo sites ... permitting a tight fit of the peptide in the substrate channel. This, together with ionic interactions between the guanidino group of Arg9 of BK and the side chains of Asp360 and Glu150 in the S2¢...
- 12
- 487
- 0
Báo cáo khoa học: Solution structure of long neurotoxin NTX-1 from the venom of Naja naja oxiana by 2D-NMR spectroscopy pot
... Consideringflexibility of l oop II in receptor binding, substitution of Gly33 with Ser (a common residue in other long neurotox-ins) may lower mobility, thereby affecting the bindingaffinity of NTX-1.Acknowledgements The ... side chains (such as Arg and Lys, similar to the corresponding residues in a-CTX that are involved in receptor binding) would be i n teresting because of the resultant alteration in the binding affinity. ... observed in other long neurotoxins.On the other hand, the absence of any NOE betweenresidues 69–73 and other regions of the peptide indicatesthat there is no s tructural involvement in this...
- 8
- 411
- 0
Tài liệu Báo cáo khoa học: Mutational analysis of plasminogen activator inhibitor-1 Interactions of a-helix F and its neighbouring structural elements regulates the activity and the rate of latency transition pdf
... behaviour of the serpin. Complex formation between serpins and their cognateproteases is fuelled by the thermodynamic properties of the serpin. Accordingly, insertion of the RCL as s4A and the ensuing ... linkage of the activesite Ser of the protease to the carboxyl group of P1by anester bond and insertion of the N-terminal part of the RCLas strand 4 in b-sheet A (s4A) of the serpin. Consequently, the ... Accordingly, we assume that the aliphatic moiety of the introduced K in PAI-1(M149K)allows the side chain to adapt the same orientation as the original M and therefore the stabilizing effect of the...
- 9
- 605
- 0
Báo cáo khoa học: Structural analysis ofN-glycans of the planarian Dugesia japonica. ppt
... Five minutes after the samplehad been injected, the concentration of ammonium acetate,pH 9.0, was increased linearly to 0.2 m in the first 20 min,Fig. 6. Sugar component analysis of pN4. The ... weretagged with the fluorophore 2-aminopyridine. Lyophilizedsamples were heated at 90 °C for 60 min with 20 lL of pyr-idylamination reagent, and then heated at 80 °C for 35 minafter the addition of ... hypothesis, it isnecessary to compare the genes involved in the synthe-sis of N-glycans in many organisms. The hypothesiswould gain strong support if lower metazoans werefound to have the...
- 9
- 405
- 0
Tài liệu Báo cáo khoa học: Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase The role of conserved residues and complementary mutations pptx
... bond with the backbone CO of F102. Fur-thermore, the orientation of the side chain of the tworesidues brings the guanidinium plane and the aro-matic ring of F102 into close proximity, with ... only criticalfor the stability of the dimer, it may also be involved in maintaining the integrity of the active site. These resultsclearly suggest that the dimer interface in the Y74W*mutant ... at these sites as in the case of TIMs from Plasmodium and yeast. Interestingly, the thioether group of M103 is positioned to make a potentially stabilizingcontact with the guanidinium group of...
- 15
- 635
- 0
Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngchuyên đề điện xoay chiều theo dạngNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíSở hữu ruộng đất và kinh tế nông nghiệp châu ôn (lạng sơn) nửa đầu thế kỷ XIXTăng trưởng tín dụng hộ sản xuất nông nghiệp tại Ngân hàng Nông nghiệp và Phát triển nông thôn Việt Nam chi nhánh tỉnh Bắc Giang (Luận văn thạc sĩ)Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)MÔN TRUYỀN THÔNG MARKETING TÍCH HỢP