Báo cáo khoa học: Binding of the viral immunogenic octapepti

Báo cáo khoa học: Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca2+ Ming Ying and Torgeir Flatmark pot

... FEBS Binding of the viral immunogenic octapeptide VSV8 to native glucose-regulated protein Grp94 (gp96) and its inhibition by the physiological ligands ATP and Ca 2+ Ming Ying and Torgeir Flatmark Section ... 2C), and the response isotherm gave a [A] 0.5 of 168 lm. Although Grp78 ⁄ BiP and Grp94 are the two major recipients...

Ngày tải lên : 30/03/2014, 11:20

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Tài liệu Báo cáo khoa học: Binding of ligands originates small perturbations on the microscopic thermodynamic properties of a multicentre redox protein pptx

... Although neither of the ligands tested is a physiological partner of cytochrome c 3 , the small changes observed for the thermodynamic properties of cytochrome c 3 bound to these ligands vs. the unbound ... of partner binding on the thermodynamic properties of the haems of cytochrome c 3 . Because the rubredoxin is a very acidic protein and binds to...

Ngày tải lên : 19/02/2014, 17:20

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Báo cáo khoa học: Binding of ATP at the active site of human pancreatic glucokinase – nucleotide-induced conformational changes with possible implications for its kinetic cooperativity doc

... binary hGK ATP complex and the domain motion induced by ATP binding to the hGK apoenzyme. (A) Close-up view of the ATP- binding site in the MD simulated model structure of the binary hGK -ATP complex, ... equilibrium binding of Glc to the ligand-free WT hGK and its binary AdN complexes was determined by its enhancement of the ITF signal (Table...

Ngày tải lên : 06/03/2014, 00:20

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Báo cáo khoa học: Binding of cGMP to the transducin-activated cGMP phosphodiesterase, PDE6, initiates a large conformational change involved in its deactivation ppt

... Pabc. The rapid increase by Pc in the level of [ 3 H]cGMP- bound Pabc trapped by the ﬁlter (Fig. 7A) might be due to a change by Pc in the surface of [ 3 H]cGMP- bound Pabc and ⁄ or in the total ... in Pabc. Together with the result showing that Pc inhibits cGMP -binding to Pabc (Fig. 6), these results imply that the scheme by which cGMP binds to P abc ﬁrst...

Ngày tải lên : 06/03/2014, 00:21

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Báo cáo khoa học: Binding of the volatile general anesthetics halothane and isoﬂurane to a mammalian b-barrel protein doc

... (http://www.microcal.com/). This software provides the best-ﬁt values for the heat of binding (DH°), the stoichiometry of binding (n), and the association constant (K a ) from plots of the heat evolved per mol of anesthetic ... shown to bind to porcine odorant binding protein [21,22] and to be competitively dis- placed by other ligands [23] shown by X...

Ngày tải lên : 07/03/2014, 16:20

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Báo cáo khoa học: Binding of activated Factor XII to endothelial cells affects its inactivation by the C1-esterase inhibitor pptx

... pulled off the cells by the binding of soluble FXIIa to the inactivator as illustrated in Fig. 3A; (b) the second mechanism assumes that the inactivator binds to FXIIa, while still bound to the cell ... directly to the cells [15,16], whereas PPK binds via a bridge generated by the ability of HK to bind to the cells as well as to PPK [17,18]. The bi...

Ngày tải lên : 23/03/2014, 20:22

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Tài liệu Báo cáo khoa học: Binding of N- and C-terminal anti-prion protein antibodies generates distinct phenotypes of cellular prion proteins (PrPC) obtained from human, sheep, cattle and mouse doc

... intensi- ties of the three PrP C bands are accredited to the development of the truncated isoforms, to the epitope recognition of the antibodies and in part to the protein structure. These data ... C-terminal binding antibodies. The signal intensity of each of the three protein bands was quantiﬁed by densitometry. The mean values of the calculat...

Ngày tải lên : 19/02/2014, 02:20

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Báo cáo khoa học: Binding of berberine to human telomeric quadruplex – spectroscopic, calorimetric and molecular modeling studies pot

... at the external G-quartet is mainly aided by the p–p interaction and the stabilization of the high negative charge density of O6 of guanines by the positively charged N7 of berberine. The theoretical ... osmolality (moles of solute per kg of solvent) of the solution, and Dn w is the difference in the number of bound water molecules between the compl...

Ngày tải lên : 16/03/2014, 06:20

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Báo cáo khoa học: Binding of non-natural 3¢-nucleotides to ribonuclease A ppt

... intensity measurement and k ¼ )30.77) and the 3¢-nucleotide con- centration in the cuvette. Each value of DF/Dt was divided by the correction factor to give the corrected value. The correction factor was the same ... pK a values. Values of K i The values of K i for the four 3¢-nucleotides were meas- ured by their ability to inhibit the cleavage of the ﬂ...

Ngày tải lên : 16/03/2014, 18:20

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Báo cáo khoa học: Localization of ﬂuorescence-labeled poly(malic acid) to the nuclei of the plasmodium of Physarum polycephalum pot

... on the amount of the probes injected, the phase of the cell cycle, and the position of the covalent linkage of the dye to the polymer. Results were indistinguishable for the low (white) and the ... nuclei. The results are in support of the simultanous transfer of polymalate and polymalatase to the surface of the nuclei, the dissociation o...

Ngày tải lên : 17/03/2014, 10:20

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