Báo cáo khoa học: The spread of prions through the body in naturally acquired transmissible spongiform encephalopathies ppt

... Spread of prions through the body FEBS Journal 274 (2007) 588–605 ª 2007 The Authors Journal compilation ª 2007 FEBS 605 MINIREVIEW The spread of prions through the body in naturally acquired transmissible ... FEBS the crossing of the gut wall, GALT-related spread of infection and intestinal neuroinvasion following inges- tion of TSE agents. Neu...

Ngày tải lên: 30/03/2014, 09:20

... potential of the haem, rate constants o f CO, O 2 and CN b inding to haem, and CD spectra in the Soret region [15–18], suggesting that this residue is critical for maintaining the electronic states of ... binding access channel a t t he haem distal side and/or structure in t erms of cyanide binding in the Fe(III) complex. Redox potentials The redox state of haem is rel...

Ngày tải lên: 19/02/2014, 16:20

... participates in the assembly of the mitotic spindle of E. focardii and that both isotypes are involved in the nucleation of other microtubule structures. Finally, we examined the distribution of E. ... been observed in E. focardii and in the psychrotolerant E. crassus [34, present study]. By contrast, the similar substitution of alanine for arginine 72 in the...

Ngày tải lên: 07/03/2014, 04:20

... Hep Hep b | Hex 2 -Hex-Hep-AnKdo-ol | Hep | Hep a Major isomer of the Hex3 glycoform (estimated from the intensity of the fragments in MS 2 experiments). b Minor isomer of the Hex3 glycoform (estimated from the intensity of the fragments in MS 2 experiments). Fig. ... most of the steps in the biosynthesis of the OS portion of their LPS molecules. Molecula...

Ngày tải lên: 08/03/2014, 02:21

... catalytic site of GalNAc-T1, might be involved in the catalytic function of the enzyme. To investigate whether the cysteine residues modified by PCMPS are involved in the binding of UDP-GalNAc, we ... a major site of interaction with UDP-GalNAc, Cys214 is also involved in binding. PCMPS and DFP modification of the serine-mutants of GalNAc-T1 We also examined the se...

Ngày tải lên: 08/03/2014, 10:20

... and that therefore the centre of scattering mass of the crossbridges in each half sarcomere is moving inwards towards the M-line, thus, decreasing the interfer- ence distance between the two halves. ... axial alignment of the catalytic domain of the head and the leverarmoccurs.Astheleverarmtiltsinaninward direction (i.e. towards the center of the sarcomere) dur...

Ngày tải lên: 16/03/2014, 16:20

... Approxi- mately half of the points drawn from C will lie in the A square, while the other half will lie in the B square. The distance of the points drawn from C from the points drawn from B will ... approximately half of the points (those laying in the B region), while the distance is be- tween 0 and h for the other half of the points (those in A). Ther...

Ngày tải lên: 17/03/2014, 22:20

... Because of the poor resolution of L6 in the FhaC structure, no information is available regarding putative interactions between the side chains of these residues and the rest of the protein. We ... conserved distance from, the C-terminus. Of note, the length of the predicted loops varies between proteins [18]. In all proteins, the Arg residue of the VRGY-...

Ngày tải lên: 23/03/2014, 03:20

... contain a signal peptide with a characteristic twin-arginine motif, while other organisms usually secrete most of their proteins (> 90%) through the Sec pathway [4,7]. The dominant role of the ... was then measured using the starch–iodine method. Minimal inhibitory concentrations of ionophores Tubes containing 5 mL of rich medium containing various concentrations of ion...

Ngày tải lên: 23/03/2014, 06:20

... 2006 FEBS the inhibition period the rate of the absorbance increase became faster, which is close to the original rate of propagation, demonstrating the exhaustion of the antioxidant. The kinetic ... and the initial concentration of the substrates are the same as described in the legends of Fig. 1 for reactions conducted in LDL. Data are the means of th...

Ngày tải lên: 23/03/2014, 10:21