Báo cáo khoa học: Glycolipids with nonreducing end a-mannosyl residues that have the potential to activate invariant Va19 NKT cells pptx
Báo cáo khoa học: Glycolipids with nonreducing end a-mannosyl residues that have the potential to activate invariant Va19 NKT cells pptx
... compilation ª 2007 FEBS Glycolipids with nonreducing end a-mannosyl residues that have the potential to activate invariant Va19 NKT cells Michio Shimamura 1 , Yi-Ying Huang 1 , Naoki Okamoto 1 , Yutaka ... Va19 NKT cells in the spleen. Thus, a-mannosyl glycolipids injected into mice possibly target Va19 NKT cells, given the lack of immune res...
Ngày tải lên: 30/03/2014, 08:20
Báo cáo khoa học: Vaccination with prion peptide-displaying papillomavirus-like particles induces autoantibodies to normal prion protein that interfere with pathologic prion protein production in infected cells pptx
... display of the PrP epitope on the PrP–VLP surface (Fig. 1D). Immunization with PrP–VLPs induces (auto-)Ab to the PrP peptide DWEDRYYRE The chosen murine prion epitope DWEDRYYRE is situated in the central ... prion-infected cells. Results PrP–L1 fusion protein self-assembles into virus-like particles (PrP–VLPs) that express the PrP-DWEDRYYRE epitope To generate chimeric V...
Ngày tải lên: 16/03/2014, 11:20
Báo cáo khoa học: Transfection with 4-hydroxynonenal-metabolizing glutathione S-transferase isozymes leads to phenotypic transformation and immortalization of adherent cells pdf
... transformation. These results further support the idea that the ability of the GST isozymes to induce transformation is dependent on their ability to conjugate 4-HNE to GSH. Furthermore, these results ... after the injection, any cells killed by the injection procedure were lifted off the dish leaving only the injected cells that survived the injection. Such cel...
Ngày tải lên: 30/03/2014, 13:20
Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx
... dose-dependently translocated first to plasma membranes and then to endosomes, in which it associates with phosphorylated IR. These results suggest that Grb14 is recruited by the activated IR at the ... lead to interesting new information on the role of this adaptor protein. The endosomal colocalization and ⁄ or cointernaliza- tion of the activated IR and Grb14 raises the...
Ngày tải lên: 18/02/2014, 18:20
Báo cáo khoa học: 7,8-Diaminoperlargonic acid aminotransferase from Mycobacterium tuberculosis, a potential therapeutic target Characterization and inhibition studies pptx
... °C. The residual activity of the enzyme solution was then measured, taking into account the dilution factor due to the dialysis step. A blank contain- ing all components but without the inhibitor ... sufficient to reverse the growth inhibi- tion. Furthermore, adding 100 lm DAPA to the med- ium in the presence of avidin also reversed the growth inhibition. Taken together...
Ngày tải lên: 07/03/2014, 11:20
Báo cáo khoa học: Identification of two cysteine residues involved in the binding of UDP-GalNAc to UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) ppt
... prT1. prT1 was linearized with BamHI, andthendigestedwithBal31 nuclease. The Bal31 digest was blunt-ended and digested with NotI. The resulting digest was ligated into the EcoRV and NotIsitesofpcDNA4, obtaining ... enzyme. The affinity for the acceptor apomucin, on the other hand, was essentially unaffected. The functional importance of the introduced serine residues was fu...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Lack of stabilized microtubules as a result of the absence of major maps in CAD cells does not preclude neurite formation pot
... be elicited [33]. The rapid retraction of neurites after the addition of serum led us to consider the possibility that the cyto- skeleton of CAD cells should have peculiar properties. Thus, in the present ... corresponding to each MAP and the absence of their mRNAs (with the exception of that of Tau) (Fig. 5). mRNA corresponding to Tau was detected in CAD cells...
Ngày tải lên: 23/03/2014, 05:22
Báo cáo khoa học: b3-Adrenoceptor knockout in C57BL/6J mice depresses the occurrence of brown adipocytes in white fat pptx
... h) before the beginning of each experiment. They were then divided into three groups, one maintained at 24 °Candthe other two exposed to cold (6 °C) for either two or 10 days. The fat pads along the ... 129Sv/ev) [23], was then backcrossed to obtain the mutation on the C57BL/6J genetic background. In the present work, we studied the effect of b 3 -adrenoceptor-deficiency on...
Ngày tải lên: 23/03/2014, 20:22
Tài liệu Báo cáo khoa học: Four divergent Arabidopsis ethylene-responsive element-binding factor domains bind to a target DNA motif with a universal CG step core recognition and different flanking bases preference pptx
... the different AtERFs. On the other hand, some other residues reported to determine the geometry of the a-helix relative to the b-sheet were not as conserved as these other residues, but instead ... CBF1. The secondary structure scheme is indicated above the sequence. The conserved amino acid residues that directly contact with DNA bases and the other conserved...
Ngày tải lên: 18/02/2014, 13:20
Tài liệu Báo cáo khoa học: "Learning with Unlabeled Data for Text Categorization Using Bootstrapping and Feature Projection Techniques" doc
... et al., 1991). The window is a slide from the first word of the document to the last in the size of the window (60 words) and the interval of each window (30 words). Therefore, the final output ... Since the keywords for text categorization must have the power to discriminate categories as well as similarity with the title words, we assign a word to the...
Ngày tải lên: 20/02/2014, 16:20