Báo cáo khoa học: Towards understanding the functional role of the glycosyltransferases involved in the biosynthesis of Moraxella catarrhalis lipooligosaccharide ppt

... [5]. In the present minireview, the expression of relaxin-3 in the brain, and particularly its functions, including the stress response and food intake, are described. Expression of relaxin-3 in the ... consists of sig- nal peptides, and a B-chain, C-peptide and A-chain, and contains the RXXXRXXI motif in the B chain (B12–B19 in human) for binding to the relaxi...

Ngày tải lên: 29/03/2014, 21:20

... and l-arginine:glycine amidinotransferase (EC 2.1.4.1) involved in creatine biosynthesis in vertebrates [26]. In cylindrospermopsin biosynthesis, the amidinotransfer- ase CyrA is thought to catalyze the ... [24,27,30,34]. The best studied amidinotransferases are l-arginine:inos- amine phosphate amidinotransferase (EC 2.1.4.2; StrB1) involved in the biosynthesis of...

Ngày tải lên: 06/03/2014, 22:21

... investigate the function of the glycosyltransferase enzymes involved in the biosynthesis of lipooligosaccha- ride of M. catarrhalis and to gain some insight into the mechanism of sero- type specificity ... strain (as proposed by Edwards et al. [5]). The elucidation of the biosynthetic pathway of LOS structures of known serotypes will allow further examination...

Ngày tải lên: 30/03/2014, 08:20

... two termini of the inserted Ca 2+ -binding sites in the model structure of the EF-hand of STIM1 is within 15 A ˚ . Accordingly, a total of six glycine linkers is suffi- cient to enable the grafted ... the initial mixture. The fluorescence intensity was normalized by subtracting the contribution of the baseline slope using logarithmic fitting. The Tb 3+ -binding affin...

Ngày tải lên: 07/03/2014, 00:20

... good inhibitors of the asymmetrical hydrolases, having K i values within the range of the K m for Ap 4 A. By contrast, none of the six analogs were good substrates or inhibitors of the bacterial ... cleavage of dinucleoside polyphosphate molecules modified in their ADP moieties. In addition, none of the oxymethylene analogs investigated inhibited the hydrolysis o...

Ngày tải lên: 16/03/2014, 04:20

... further verifying formation of a complex between NrpRI and NrpRII. The presence of 10 mm 2-oxoglutarate significantly decreased the binding of MBP–NrpRI to the operator as well as the binding of the ... complete loss of repression in M. maripaludis, whereas the muta- tion of the corresponding amino acid in the first NrpR domain (S168A) retained a normal regulatio...

Ngày tải lên: 29/03/2014, 21:20

... + AC chain. 4.1 The Role of Lexical Clustering The first study aims at detecting the impact of dif- ferent clustering policies on the resulting AC ac- curacy. Clustering, as discussed in Section ... about the relation r. In ANC the percentage of times that the Eq. 5 is backed off against test instances (as h or r are not available from the training data) is twice as...

Ngày tải lên: 30/03/2014, 21:20

... from the results listed in Table 1 that most, if not all, of the amylose is synthesized in vivo when the rate of amylopectin synthesis becomes minimal. At these moments the rates of amylopec- tin ... further distinguished from glycogen by the presence of highly ordered parallel arrays of double helical glucans (reviewed in [5]). The origin of these arrays resides...

Ngày tải lên: 22/02/2014, 07:20

... identi- fication of their actin-binding domains. To date, none of the actin-binding domain sequences registered in databases is present in hhLIM or CRPs. The goals of this study were to define the actin-binding ... the second LIM domain plays a central role in bundling of F-actin. Taken together, these data identify hhLIM as an actin-binding protein that increases actin...

Ngày tải lên: 16/03/2014, 06:20

... step increase of 0.2 nm, and a bandwidth of 1 nm. Thermal stability of Rep245 was measured by incu- bating the protein at 60, 70 and 80 °C for 30 min and then recording the CD spectra of the incubated ... structure–sequence analysis The N-terminal domain comprising residues 31–245 of the orf915-encoded putative replication protein of the plasmid pIT3 was predicted to b...

Ngày tải lên: 18/02/2014, 18:20