... acyl chain length and degree of unsaturation, the number of ionizable aminesin the polar headgroup, and the spatial arrangement of the hydrophobic and hydrophilic regions within the lipidmolecule ... with the poorly active deri-vative 1,3lb4, of lipid mixing of the active compoundswith anionic vesicles.Lipids of the 1,3lb series were synthesized with the intent of enhancing the transport of ... instead of the transition midpoint, the all liquid-expanded states at 23 °C and 37 °C of the dipalmitoyl and distearoyl derivatives, respectively, inmonolayers complement the nature of these lipids...