Báo cáo khoa học: Allosteric modulation of Euphorbia peroxidase by nickel ions pdf

... lost. The effect of Ni 2+ in the absence of added CaCl 2 was determined by inverse plots of the steady-state kinetics at saturating concentrations of ABTS (10 mm) Nickel ions and Euphorbia peroxidase ... (2008) 1201–1212 ª 2008 The Authors Journal compilation ª 2008 FEBS Allosteric modulation of Euphorbia peroxidase by nickel ions Francesca Pintus 1 , Anna Mu...

Ngày tải lên: 30/03/2014, 04:20

... presence of saturating concentrations of myristate, the tendency of the curve to become sig- moidal is much attenuated, suggesting a substantial impairment of allosteric modulation by myristate ... state HSA transition, and appear of general significance for a deeper understanding of the allosteric modulation of ligand binding properties of HSA. Abbreviations FA, fatt...

Ngày tải lên: 20/02/2014, 02:22

... included to inhibit the feedback proteolysis of prothrombin by the generated thrombin). The reaction was stopped by the addition of an equal volume of acetic acid, and the resulting mixture was ... model. Therefore, the dual modulation of prothrombin activation by plactin may be interpreted as leading to anticoagulation under physiological coagulat- ing conditions. Abbreviatio...

Ngày tải lên: 07/03/2014, 00:20

... development of effective therapeutic strategies is hampered by a paucity of information on the biolo- gical mechanisms underlying the disease. The severity of AD relates to a multitude of age-related ... that the loss of hippocampal synapses in rat organotypic slices is mediated by Ab oligomers and is dependent on the activity of NMDA- type glutamate receptors. The concentrati...

Ngày tải lên: 07/03/2014, 10:20

... soluble VFTs [32]. However, this may be explained by the absence of the other part of the receptor (the CRD and the HD), as well as by the absence of cations that stabilize the Acc state. Although ... functioning of class C GPCRs and illustrate how allosteric inter- actions between the subunits play a fundamental role in their activation. Of interest, we see that this com- ple...

Ngày tải lên: 07/03/2014, 21:20

... been approved by the Human Research Ethics Committee of Trento University. REC is by now made up of 17 dyadic interac- tions, 9 with confederate, for a total of 204 min- utes of audiovisual ... predic- tions are made on the speaker role. 4 Conclusions and Future Directions Cooperative behavior and its relationship with emotions is a topic of great interest in the field of...

Ngày tải lên: 08/03/2014, 01:20

... (1994) Functions of individual gamma-carboxyglutamic acid (Gla) residues of human protein C. Determination of functionally nonessential Gla residues and correlations with their mode of binding ... of protein C from sEPCR was achieved by injection of HBS-EP buffer, containing 3m M EDTA. 3, Injection of 10 mM glycine ⁄ HCl pH 2.5 regenerated the antibody surface by the complet...

Ngày tải lên: 16/03/2014, 18:20

... channel of E1 such that (a) formation of 8-(S)-acetyl-dihydrolipoylamide is more likely than of the 6-S isomer and (b) protonation of the lipoamide dithiolane by His407 K. Tittmann Redox reactions of ... conducted by Frey et al. on the E2-catalyzed acetylation of free dihydrolipoamide by acetyl-CoA clearly revealed formation of the 8-S isomer, followed by non-enzymatic i...

Ngày tải lên: 18/02/2014, 08:20

... adversely affect cellular function by direct effects on a variety of enzymes and induction of apoptosis [4]. Tight regulation of intracellular concentrations of free LCACs by acyl-CoA-binding protein ... concentrations and Dw [16]. The relative contribution of a particular enzyme to the control of metabolic pathway flux and concentrations of reaction intermediates determines...

Ngày tải lên: 19/02/2014, 05:20

... Classification of Medical Assertions in Clinical Notes Youngjun Kim Ellen Riloff Stéphane M. Meystre School of Computing School of Computing Department of Biomedical Informatics University of ... more efficient ways to process increasingly large collections of clinical narratives. As evidence of this transition, nearly all of the best-performing systems in the Fou...

Ngày tải lên: 20/02/2014, 05:20