Báo cáo khoa học: Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells docx
Báo cáo khoa học: Effect of ecdysone receptor gene switch ligands on endogenous gene expression in 293 cells docx
... signifi-
cant changes in the expression of host genes.
AMK, RG-121150, affects gene expression in
293 cells
The affect of the AMK RG-121150 on gene expression
in 293 cells was analyzed using microarray ... changes in expression of endogenous genes in 293 cells and
therefore should have minimum pleiotropic effects when used as ligands
for the ecdys...
Báo cáo Y học: Effects of ATP depletion and phosphate analogues on P-glycoprotein conformation in live cells docx
... accompanied by
complementary changes in MM12.10 binding also in re-
sponse to direct modulation of the ATP-binding site, con-
firming that conformational changes intrinsic to the catalytic
cycle are ... UIC2
binding in the presence of substrates/modulators is applied
as an indicator of the expression of functional Pgp
molecules in clinical tissue samples [20]. Changes in th...
Báo cáo khoa học: Improvement of ecdysone receptor gene switch for applications in plants: Locusta migratoria retinoid X receptor (LmRXR) mutagenesis and optimization of translation start site pptx
... conditional regulation of transgene expression by
the interaction of a chemical inducer with a designed
receptor or transcription factor is a powerful tool for
the regulation of transgenes in ... undetectable level
of transgene expression in the absence of a chemical
ligand, followed by rapid and robust induction of
transgene expression in the presence of a low con...
Báo cáo khoa học: "Effect of intern’s consecutive work hours on safety, medical education and professionalism"
... rapidly increases after 16 hours of sustained
wakefulness, a finding reflected in the twofold increase in
interns’ attentional failures after they had been working for
more than 16 hours on the ... comments, including clarification of the
power, sample size, and statistical approach descriptions that
appeared in our recent Journal Club review [1] of their
studies examining the...
Tài liệu Báo cáo khoa học: Effect of sequence polymorphism and drug resistance on two HIV-1 Gag processing sites pdf
... 2).
Increasing the concentration of the NC/p1 substrate above
the K
m
resulted in a decreased velocity, suggesting the
possibility of increased nonproductive binding at the
substrate binding ... residues are in bold.
b
The type of mutation: natural polymorphism (P), mutation appearing only in drug resistance (R, see
Fig. 1). If two mutations occurred and one of them was occurrin...
Báo cáo khoa học: Effect of mutations at Glu160 and Val198 on the thermostability of lactate oxidase doc
... The
secondary-structure nomenclature is according to Lindqvist [19]. The picture was created using
INSIGHT II
software (Version 4.3, Accelrys Inc.) on an
ONYX2 workstation (Silicon Graphics, Inc.).
Fig. ... forming a hydrogen-bond network between
the NH
2
of Arg143 and the main-chain carbonyls of Lys181
and Asn182 directly, and the main-chain carbonyl of
Glu184 by way of a water mol...
Báo cáo khoa học: Interaction between catalytically inactive calpain and calpastatin Evidence for its occurrence in stimulated cells docx
... presence of
Ca
2+
, the addition of equimolar amounts of calpasta-
tin induces an increase of approximately one order of
magnitude in the affinity of calpain for mAb 56.3,
indicating that, in these conditions, ... for interaction with calpain.
This hypothesis is confirmed by the effect of arachi-
donate treatment on the intracellular distribution of
calpastatin (Fig. 8)....
Báo cáo khoa học: Cdk2 activity is dispensable for triggering replicon initiation after transient hypoxia in T24 cells docx
... elevated concentration
of staurosporine.
Effects of Cdk2 inhibition on pRb, Cdc6 and
PCNA in vivo
In Fig. 4 we analysed the effects of the Cdk2 inhibitors
olomoucine, roscovitine and staurosporine ... incubation condition (data not
shown). This suggests that in T24 cells inhibition of
the pRb pathway is not the direct cause of the hypoxic
suppression of initiation in r...
Tài liệu Báo cáo khoa học: Effect of gadolinium on the ryanodine receptor/ sarcoplasmic reticulum calcium release channel of skeletal muscle docx
... the
visualization of the protein composition of the fractions.
Ryanodine-binding
Ryanodine-binding assays were carried out using [
3
H]ry-
anodine in a medium having the composition of 1 m NaCl,
S. ... released. The effect of 5 lm gadolinium on the
[
3
H]ryanodine binding to the HSR was investigated at
different ryanodine concentrations. Gadolinium (5 lm)
Table 1. The effect...
Báo cáo khoa học: " Effect of the medical emergency team on long-term mortality following major surgery"
... glycopeptides only, and Stenotropho-
monas maltophilia, sensitive to ofloxacin only. Polymicrobial
wound contamination also included contamination with fungi
(for instance, Candida albicans as well as non-albicans ... tract
Tsunami near-drowning involved the aspiration of immersion
fluids as well as marine and soil debris into the respiratory
tract, thus producing intrapulmonary inoculation...