... 59.1 K m 11.9 ± 2.9 5–1 2 [35] 10.4 ± 2.6 – 10.4 ± 2.6 – 10.4 ± 2.6 – K i 4.1 ± 0.8 2.5 [36] 4.1 ± 0.8 – 4.1 ± 0.8 – 4.1 ± 0.8 – r 0.91 ± 0.43 – 0.76 ± 0.14 – 0.99 ± 0.27 – 1.24 ± 0.45 – Hexoses fi sucrose (Hxk, ... 6.1 K m 10.5 ± 2.7 5–1 2 [35] 12.1 ± 1.9 – 12.1 ± 1.9 – 12.1 ± 1.9 – K i 1.7 ± 0.3 2.5 [36] 1.7 ± 0.3 – 1.7 ± 0.3 –...
Ngày tải lên: 14/02/2014, 22:20
... studies. The high selectivity of the a-conotoxins, together with the possibility of obtaining detailed information on their three dimen- sional structures and the relative ease of synthesis, makes them ... snail tissues. The analysis of the DNA of different Conus species has already revealed a large number of a-conotoxin sequences [45] and the identification of furt...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: Local stability identification and the role of a key aromatic amino acid residue in staphylococcal nuclease refolding pdf
... that the apparent association constant of SNase( 1–1 26) bound to pdTp in the presence of Ca 2+ is approxi- mately threefold lower than that of the wild-type pro- tein. Therefore, some or all of the ... from either repla- cing the tryptophan at position 140 with alanine or the removal of a fragment from positions 14 0–1 49. This is supported by the melting points...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo khoa học: Concepts and tools to exploit the potential of bacterial inclusion bodies in protein science and biotechnology pdf
... in the cell, chaperones are saturated and the equilibrium shifts toward the free version of r 32 , leading to induc- tion of the stress response. Nevertheless, the nature and variability of the recombinant ... native a-helices of the N-terminal 185 residues of the functional domain of the HA2 subunit of the influenza virus hemagglutinin protein and to detect c...
Ngày tải lên: 06/03/2014, 00:20
Báo cáo khoa học: Adipocyte hyperplasia and RMI1 in the treatment of obesity doc
... result of the disruption of the homeostasis between food intake and energy expendi- ture, and therefore factors affecting these processes are the focus of extensive research targeting the develop- ment ... cell-cycle regulation The mode of action of RMI1 in the regulation of energy homeostasis might be based on the regulation of adipocyte hyperplasia. Studies have...
Ngày tải lên: 06/03/2014, 01:20
Báo cáo khoa học: Neural retina leucine-zipper regulates the expression of Ppp2r5c, the regulatory subunit of protein phosphatase 2A, in photoreceptor development pdf
... increase 2 0 Mock Mock Flag–Nrl Flag–Nrl Fold increase Ppp2r5c promoter 25 Luciferase NRE : WT Luciferase : ΔNRE Luciferase NRE : NRE –8 7 –8 00 –7 4 –2 60 ** *** 5 10 15 20 25 *** *** 0 5 Flag–Nrl Flag–Nrl Flag–Nrl Flag–Nrl Reporter ... (1996) High complexity in the expression of the B¢ subunit of protein phospha- tase 2A0. Evidence for the existence of at least seven...
Ngày tải lên: 06/03/2014, 02:20
Báo cáo khoa học: Interaction between Lim15/Dmc1 and the homologue of the large subunit of CAF-1 – a molecular link between recombination and chromatin assembly during meiosis pot
... pGBKT7 or pGADT7 empty vector. Transformants were then plated onto three types of selection medium: SD2, –Leu/–Trp; SD3, –His/–Leu/–Trp; SD4, –Ade/–His/–Leu/–Trp. b-Galactosidase assays were performed ... Because of the vari- ous interactions of Lim15/Dmc1–CAF-1–PCNA, we suggest that they act in multiple ways at the site of meiotic recombination and contribute to the subse- quen...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: Local stability identification and the role of key acidic amino acid residues in staphylococcal nuclease unfolding ppt
... lower than that of the wild-type protein. The thermodynamic parameters of the glycine susti- tution mutants also differed greatly from the wild-type protein. The T m values of these mutants ranged ... 396 7–3 974 ª 2005 FEBS 3969 residue substitution on the destabilization of secondary structure that leads to the large perturbation of the stability of the prote...
Ngày tải lên: 07/03/2014, 21:20
Báo cáo khoa học: "Case markers and Morphology: Addressing the crux of the fluency problem in English-Hindi SMT" pot
... Proceedings of the 47th Annual Meeting of the ACL and the 4th IJCNLP of the AFNLP, pages 80 0–8 08, Suntec, Singapore, 2-7 August 2009. c 2009 ACL and AFNLP Case markers and Morphology: Addressing the ... likely. The separation of the lemma and suffix helps in tiding over the data sparsity problem by allowing the system to reason about the suffix-case marker com-...
Ngày tải lên: 08/03/2014, 00:20
Báo cáo khoa học: "Speech Technology: from Research to the Industry of Human-Machine Communication" potx
Ngày tải lên: 08/03/2014, 01:20