Báo cáo khoa học: Par j 1 and Par j 2, the two major allergens in Parietaria judaica, bind preferentially to monoacylated negative lipids potx
Báo cáo khoa học: Par j 1 and Par j 2, the two major allergens in Parietaria judaica, bind preferentially to monoacylated negative lipids potx
... Parietaria allergens behave as ns-LTPs FEBS Journal 276 (2009) 17 62 17 75 ª 2009 The Authors Journal compilation ª 2009 FEBS 17 75 Par j 1 and Par j 2, the two major allergens in Parietaria judaica, bind ... 01 319 1 E-mail: gbbviria@lg.ehu.es (Received 5 November 2008, revised 5 January 2009, accepted 19 January 2009) doi :10 .11 11 /j. 17 42-4658.2...
Ngày tải lên: 30/03/2014, 02:20
Báo cáo khoa học: Eukaryotic class 1 translation termination factor eRF1 ) the NMR structure and dynamics of the middle domain involved in triggering ribosome-dependent peptidyl-tRNA hydrolysis pptx
... explained by their competitive inhibition at the ribosome-binding site [32]. Together, the M and C domains of human eRF1, in the absence of the N domain, are able to bind to the mammalian ribosome and induce ... )35 Gln185 )90 ± 23 13 5 ± 7 )11 0 ± 17 )75 13 5 )60 Ser186 )68 ± 5 14 8 ± 4 0 ± 11 0 )73 15 0 b Ala187 )64 ± 1 ) 41 ± 2 )64 )42 Leu188 )64 ± 1 )42 ±...
Ngày tải lên: 07/03/2014, 05:20
Báo cáo khoa học: nNOS inhibition, antimicrobial and anticancer activity of the amphibian skin peptide, citropin 1.1 and synthetic modifications pot
... c-CH 3 1. 10, 1. 00 66.0 17 6.7 Ala10 8.83 4.02 1. 53 54 .1 178.6 Ser 11 7.83 4 .17 4 .12 , 4.03 60.7 17 4.7 Val12 7. 91 3.85 2. 41 c-CH 3 1. 13, 1. 02 64.8 17 6.9 Ile13 8.28 3. 81 2. 01 c-CH 2 1. 73, 1. 34 63.5 17 7.2 c-CH 3 0.99 d-CH 3 0.88 Lys14 ... multocida a 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 10 0 Staphyloccus aureus 25 25 10 0 25 10 0 25 10 0 25...
Ngày tải lên: 17/03/2014, 09:20
Báo cáo khoa học: Total chemical synthesis and NMR characterization of the glycopeptide tx5a, a heavily post-translationally modified conotoxin, reveals that the glycan structure is a-D-Gal-(1fi3)-a-D-GalNAc pot
... doi :10 .11 11 /j. 14 32 -10 33.2004.04464.x total, nine of the 13 residues in tx5a are modified, making it one of the most highly modified gene products identified to date. The native peptide was purified to ... monitoring to check the efficiency of the coupling reactions. In order to scale up t he automated synthesis to the same level as the manual synthesis (280 l...
Ngày tải lên: 23/03/2014, 13:20
Tài liệu Báo cáo khoa học: Oxidized elafin and trappin poorly inhibit the elastolytic activity of neutrophil elastase and proteinase 3 pdf
... elafin and trappin Elafin and the inhibitory domain of trappin each have two methionine residues (M25 and M 51 for elafin, and M63 and M89 for trappin). M25 and M63 are the P 1 ¢ residues of the inhibitors’ ... sequence homologous to a putative transglutaminase substrate motif. The trappin molecule may therefore be cova- lently attached to other proteins [11 ]. These...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Substrate specificity and transport mode of the proton-dependent amino acid transporter mPAT2 potx
... alanine, serine and proline but also osmolytes such as sarcosine and betaine, and the D -enantiomers of serine and alanine. The apparent affinities of PAT1 substrates are mainly in the range of 2 15 m M [1, 2,4 ,6,9]. ... glycine and alanine were a ble to induce comparable inward currents in oocytes expressing PAT2 with a h igh affinity interaction ( Fig. 1A and Table...
Ngày tải lên: 07/03/2014, 16:20
Báo cáo khoa học: Connection of transport and sensing by UhpC, the sensor for external glucose-6-phosphate in Escherichia coli ppt
... 14 5 75 93 81 932 R 318 C 45 14 5 81 179 Constitutive a R 318 A 73 15 2 63 2 41 Constitutive a R 318 K 15 0 10 6 67 15 8 Constitutive a R437C 11 5 10 0 12 8 78 15 .2 Salt bridge T382D/V385K 16 0 15 0 10 15 00 n.m. Loop ... 63 11 0 10 0 11 0 3.8 Arginine mutants R46C 13 5 10 5 22 480 n.m. R149C 30 15 4 39 395 2646 R152C 23 30 13 2 31 0.86 R152A 46 9 37 24 3.2 R152K 82...
Ngày tải lên: 08/03/2014, 08:20
Báo cáo khoa học: Dual mitochondrial localization and different roles of the reversible reaction of mammalian ferrochelatase ppt
... corresponding to the two ferrochelatase activities (Fig. 1B), were examined in the mitochondria and cytosol. The activity of cytochrome c oxidase, an inner membrane protein, was only found in the mito- chondrial ... is cleaved during the processing into the inner membrane of mitochondria [1] . Because ferrochelatase in the outer membrane has a molecular mass similar...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo khoa học: Site-directed mutagenesis and footprinting analysis of the interaction of the sunflower KNOX protein HAKN1 with DNA ppt
... the footprint. Letters to the right of each panel indicate the DNA sequence (5¢ end in the upper part) of the corresponding strand in this region. In the lower part, the sequence of the binding ... family. Results Expression and DNA binding analysis of the HAKN1 homeodomain The homeodomain of the KNOX transcription factor HAKN1 was expressed in Escherichia co...
Ngày tải lên: 23/03/2014, 13:20
Báo cáo khoa học: Phosphatidylserine induces functional and structural alterations of the membrane-associated pleckstrin homology domain of phospholipase C-d1 docx
... Ala 116 and Ala 118 within the C-terminal a3-helix of the PH domain are unchanged. These signals are indifferent to the presence of the membranes, probably because the positions of Ala 116 and Ala 118 ... to the chemical shift and line shape of the peak representing Ala 112 in the PH domain bound to IP 3 in solution. The matching of chemical shifts of Ala88...
Ngày tải lên: 30/03/2014, 10:20