Báo cáo khoa học: Synergistic co-operation of signal transducer and activator of transcription 5B with activator protein 1 in angiotensin II-induced angiotensinogen gene activation in vascular smooth muscle cells potx
... an
additive to prevent inactivation and aggregation of heat-
labile proteins.
Keywords: arginine; arginine ethylester; lysozyme; protein
aggregation; thermal inactivation.
Protein a ggregation is ... the
problems of protein aggregation and misfolding. Recently
we reported that polyamines, typically spermine and
spermidine, prevent heat-induced inactivation and aggre-
gation...
... expression of tissue- and
urinary-type plasminogen activator and plasminogen
activator inhibitor 1 and 2. J Cell Biol 10 6, 9 71 978.
84 Medcalf RL (19 92) Cell- and gene- specific interactions
between signal ... binding sites for several
ARE binding proteins, including the stabilizing protein
HuR [86] and the mRNA destabilizing protein tristetr-
aprolin (TTP) [87]. H...
... families of proteins were in the
N-terminal and C-terminal regions [11 ]. In order to
distinguish between the two protein families in greater
detail, a comparative analysis of TLP and transthy-
retin ... Richardson SJ
(2006a) Structural and functional evolution of transthy-
retin and transthyretin-like proteins. Proteins: Struct
Funct and Bioinf 64, 10 24 10 45.
12 R...
... ischemic injury and
pain. J Pharmacol Sci 10 0, 4 61 470.
11 1 Allan SM & Rothwell NJ (20 01) Cytokines and acute
neurodegeneration. Nat Rev Neurosci 2, 734–744.
11 2 Rothwell N (2003) Interleukin -1 and ... increase very early following permanent
MCAO [11 5 ,11 6] and peak within hours of reperfusion
in transient focal ischemic models in rodents
[97 ,11 7 ,11 8]. The ma...
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Glutamine 2.8 ± 0.5 440.5 ± 28.7 15 7.3 4 14 7.8 0.04 1. 8
Phenylalanine 1. 7 ± 0.3 91. 0 ... 0.9 215 .4 ± 14 .4 33.7 6.3 11 6.6 0. 012 < 0.05
Tyrosine 3.2 ± 0.4 91. 0 ± 4.8 28.4 200 15 4.7 0.00 31 < 0....
... strain NF54 with
P. falciparum strain K1 [17 ] and P. yoelli
(NCBI:AA18892) u sing
CLUSTAL W
[24].
Enolase from s train N F54 diff ers fro m that of
strain K1 in having a P131A mutation (shown
in ... strains
differ from the K1 strain at position 13 1 in having an
alanine residue in place of a proline. Figure 1 shows a
comparison of amino-acid sequences of enolases from
P...
... example is concerned with insulin signaling, and is
inspired by the developments in [12 ]. Insulin signaling
occurs via the insulin receptor (IR). The IR signaling
processes may be inspected experimentally ... initial
mass is in states x
1
and x
2 ,1
, the corresponding set of
differential equations are:
_
x
1
¼Àk
1
x
1
þ 0:001x
2 ;1
13 aÞ
_
x
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¼Àk
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x
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þ k
m 1...
... 4-matrix
metalloproteinase and binding of the activated proteinase
to chondroitin sulfate and heparan sulfate on syndecan-
1. J Biol Chem 279, 10 042 10 0 51.
34 Hausser H & Kresse H (19 91) Binding of heparin
and ... FEBS
maintained in DMEM alone. However, in cultures
maintained in DMEM containing 10 0 and
10 00 lgÆmL
)1
CaPPS, the percentage of
35
S-labeled
pr...
... J. Inorg. Biochem. 12 , 323–334.
10 . Lee, B.H. & Nowak, T. (19 92) In uence of pH on the Mn
2+
activation of and binding to yeast enolase: a functional study.
Biochemistry 31, 216 5– 217 1.
11 . ... production of a fusion protein bearing
an N-terminal extension of 20 residues including a (His)
6
-
tag and a thrombin cleavage site, leaving three amino
acids (Gly-Ser-Hi...