Báo cáo khoa học: Membrane compartments and purinergic signalling: the role of plasma membrane microdomains in the modulation of P2XR-mediated signalling pot
Tài liệu Báo cáo khoa học: A second novel dye-linked L-proline dehydrogenase complex is present in the hyperthermophilic archaeon Pyrococcus horikoshii OT-3 pptx
... at the interface between the a and b subunits. A comparison of the amino-acid sequences showed that the ADP-binding motif in the a subunit of PDH1 clearly differs from that in the a subunit of ... stream from the 5¢-terminus of the predic- ted ORF, is the proper initial codon for a2. The N-ter- minal amino-acid sequences of the b2 and c2 subunits corres...
Ngày tải lên: 20/02/2014, 01:20
Báo cáo khoa học: Abortive translation caused by peptidyl-tRNA drop-off at NGG codons in the early coding region of mRNA potx
... inhibit growth of the strain even in the presence of IPTG induction. All of these results suggest that the low gene expression associated with NGG codons in the down- stream region following the initiation ... paus- ing at early NGG codons is the reason for the observed low gene expression. The length of the peptidyl moiety of the peptidyl- tRNA in uences t...
Ngày tải lên: 30/03/2014, 20:20
Báo cáo khoa học: Activated transglutaminase from Streptomyces mobaraensis is processed by a tripeptidyl aminopeptidase in the final step pptx
... N e -(c-glutamyl)lysine bonds, the incorpor- ation of polyamines into proteins, the deamidation of protein-bound glutamines, and the covalent attachment of proteins to lipids such as x-hydroxyceramides ... distinct differ- entiation stages. Culture on agar plates containing glucose, yeast and malt extracts allows the organism to develop substrate and aerial mycelia culmina...
Ngày tải lên: 31/03/2014, 07:20
Tài liệu Báo cáo khoa học: Purification and characterization of a membrane-bound enzyme complex from the sulfate-reducing archaeon Archaeoglobus fulgidus related to heterodisulfide reductase from methanogenic archaea pdf
... locus of A. vinosum, the DsrJ protein. The mature form of the AF503 protein contains an N-terminal hydrophobic s tretch predicted to form a transmembrane a helix, which may anchor the protein in the ... DsrK, and HmcF clearly identified the t wo typical CXXCXXCXXXCP binding motifs for [4Fe-4S] clusters in the N-terminal part of these proteins. AF502, DsrK, and HmcF...
Ngày tải lên: 21/02/2014, 03:20
Báo cáo khoa học: Trafficking and proteolytic processing of RNF13, a model PA-TM-RING family endosomal membrane ubiquitin ligase pot
... ubiquitination in endosomes, on the plasma membrane, in the cytoplasm, in the nucleoplasm or on the inner nuclear membrane, with the site(s) regulated by signaling events that modulate protein targeting and ... tags and RNF13 CTFs are found in purified INM fractions [46]. This signal-induced movement to the INM places the RING domain in the nucleoplasm and...
Ngày tải lên: 15/03/2014, 00:20
Báo cáo khoa học: Lipid droplet and milk lipid globule membrane associated placental protein 17b (PP17b) is involved in apoptotic and differentiation processes of human epithelial cervical carcinoma cells pptx
... peptide map, and most of the input masses were matched to the candidate protein sequences. The majority of the tryptic peptides matched with the theoretical masses within 62 p.p.m. MALDI-TOF MS data of the ... adipo- philin and perilipin genes have been revealed, and analysis of the 5¢ flanking region of the PP17 gene has shown a number of potential transcript...
Ngày tải lên: 23/03/2014, 21:20
Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx
... [ 125 I]TC-PCSK9 binding to HepG2 cells (data not shown), further supporting the specificity of the binding. Estimation of binding affinity of wild-type and two mutant variants of PCSK9 In preliminary saturation ... First, the number of LDLRs on HepG2 cells increased following growth in the absence of lipo- proteins, and there was a corresponding increase in the...
Ngày tải lên: 14/02/2014, 14:20
Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... domain of t-bet, the STAT protein inter- action domain, STAT protein all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-finger domain, leucine-zipper domain and ... proteins, a leucine zipper domain and a C2H2 zinc finger domain, both of which are thought to help mediate DNA binding and may be involved in the induction of dimerizati...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Pronounced adipogenesis and increased insulin sensitivity caused by overproduction of prostaglandin D2 in vivo pptx
... we show, for the first time, that PGD 2 is involved in the activation of adipogenesis and regula- tion of insulin sensitivity in vivo. Further characteriza- tion of the role of PGD 2 in adipocyte ... more in WAT of TG mice than in WAT of WT mice. Serum levels of triglyceride, glucose, leptin and insulin, and insulin sensitivity, in TG mice After 6 weeks...
Ngày tải lên: 16/02/2014, 09:20
Tài liệu Báo cáo khoa học: Neuropeptide Y and osteoblast differentiation – the balance between the neuro-osteogenic network and local control ppt
... conditions of elevated leptin and NPY by overexpressing NPY in the hypothalamus of Y2 ) ⁄ ) mice [25]. These animals had a marked increase in leptin levels, and thereby an increase in body weight and ... 3665 (ruling out the possibility of an autocrine, paracrine or endocrine mechanism of regulation in the ob ⁄ ob model), and given that the majority of leptin...
Ngày tải lên: 18/02/2014, 04:20