... mAb TC2 plus pairs3-9 ⁄ 5H2, 3-9 ⁄ 3C12, 4-7 ⁄ TC7, 2-2 ⁄ 3C12, TC4 ⁄ 5H2,TC4 ⁄ TC7, TC4 ⁄ 3C12; and (b) capturing mAb 3-9 pluspairs 4-7 ⁄ 3C4, 2-2 ⁄ 3C4.Synthesis of biotinylated CblCbl ... 3-9 was used for pairs 4-7 ⁄ 3C4and 2-2 ⁄ 3C4, where binding of the second mAb of thepair was inhibited by < 20%.Interaction of mAbs with the C-terminal domain of human TC was determined using ... 11% of maximal radioactivity, suggestingthe matching epitope to be partially upstream of thesequence T326QEII…Effect of S-S reductionAll antibodies under study recognized recombinant human...