Báo cáo khoa học: The ubiquitin-like protein monoclonal nonspecific suppressor factor b conjugates to endophilin II and regulates phagocytosis potx

... The < /b> ubiquitin-like < /b> protein < /b> monoclonal < /b> nonspecific < /b> suppressor < /b> factor < /b> b conjugates to endophilin II and regulates phagocytosis Morihiko Nakamura and Shunsuke Shimosaki Department ... and peritoneal macrophages, because endophilin II is a member of the < /b> endocytic endophilin family. We observed two bands (62 kDa MNSFb...

Ngày tải lên: 29/03/2014, 22:21

... subdomain VII of the < /b> catalytic domain and by the < /b> presence of an amino acid insertion of variable size between subdomains VII and VIII [8,9]. Such as OXI, other AGC kinases of the < /b> AGC VIII subgroup have ... confers resistance to the < /b> bacterial pathogen P. syringae pv tomato carrying the < /b> avirulence effector proteins AvrPto or AvrPtoB [17,18]. The < /b>...

Ngày tải lên: 14/02/2014, 19:20

... organization as authentic mature capsids have been obtained by self- assembly of CA in vitro, even in the < /b> absence of any other biomolecule, and subjected to structural, bio- chemical and mutational ... validated and extended to higher resolution, and it may be far from complete. In addition to CA, other Gag domains and other proteins are known or suspected to play imp...

Ngày tải lên: 18/02/2014, 06:20

... inhibitors; (b) nucleotide reverse transcriptase inhibitors; and (c) protease inhibi- tors [1]. Because of the < /b> poorly understood side-effects of protease inhibitors in human fat metabolism [2], and ... which bind to: (a) CTD (or CA) monomers and occupy the < /b> dimerization interface or (b) nearby sites to the < /b> dimerization interface, thus weak- ening the < /b> bindi...

Ngày tải lên: 18/02/2014, 06:20

... proposed to be most crucial to yield infor- mation on the < /b> specificity of binding of particular vs. bulk lipids, the < /b> number of their binding sites and the < /b> occupancies and the < /b> cooperativity of their ... [25] and local anaesthetics [26]. The < /b> nAChR is the < /b> by far best-characterized mem- ber of the < /b> superfamily of ligand-gated ion channel pro...

Ngày tải lên: 19/02/2014, 18:20

... anti-T7) was then used to monitor the < /b> location of the < /b> epitope-tagged region with respect to the < /b> KdpD protein < /b> in the < /b> membrane. The < /b> KdpD protein < /b> with the < /b> epitope tags was readily digested by proteinase ... from the < /b> membrane surface and easily accessible by the < /b> protease. To address the < /b> role of SecA in the < /b...

Ngày tải lên: 20/02/2014, 11:20

... cap the < /b> top and bottom of the < /b> barrel (Fig. 3) [36,37]. The < /b> active site, in a hydrophobic pocket on the < /b> protein < /b> sur- face, is the < /b> binding site of CsA and its analogs. Muta- tional analyses and ... correlation between their ability to be incorpo- rated into virions and their ability to undergo aminoa- cylation [11]. Because the < /b> amino...

Ngày tải lên: 07/03/2014, 00:20

... the < /b> membrane. The < /b> cyto- chrome c 1 precursor is translocated along the < /b> Sec translocon; its heme cofactor is exported to the < /b> peri- plasm and attached to the < /b> apo -protein < /b> by the < /b> c-type cytochrome ... (a) the < /b> inability of the < /b> mutant to insert a cofactor, and (b) the < /b> specific origin of the < /b> signal in the < /b> o...

Ngày tải lên: 07/03/2014, 11:20

... HMGN2 elevates the < /b> activity of NF-jB, enhances the < /b> amount of NF-jB p65 in the < /b> nucleus and regulates the < /b> equilibrium between HATs and HDACs thereby affecting p65 acet- ylation; and (b) HMGN2 itself ... proliferation, invasion, and inflammation through inhibition of the < /b> inhibitory subunit of nuclear factor-< /b> jBa kinase, leading to potentiation...

Ngày tải lên: 22/03/2014, 16:20

... structures have been submitted to WormBase and EMBL/GenBank/DDBJ databases (for accession number, see footnote). The < /b> genes Table 2. (Continued). Gene name Wormpep name EMBL/GenBank Genetic map position ... lumen of the < /b> terminal bulb (Fig. 1B, arrows). Therefore, NAS-4 most likely is secreted by the < /b> pharynx cells into the < /b> lumen and then is found in secreted fo...

Ngày tải lên: 23/03/2014, 15:21