... HMGN2 elevates the < /b> activity of NF-jB, enhances the < /b> amount of NF-jBp65 in the < /b> nucleus and regulates the < /b> equilibriumbetween HATs and HDACs thereby affecting p65 acet-ylation; and (b) HMGN2 itself ... proliferation,invasion, and inflammation through inhibition of the< /b> inhibitory subunit of nuclear factor-< /b> jBa kinase, leading to potentiation of apoptosis. Blood 111, 4880–4891.27 Reeves R & Candido EP (1980) ... because the < /b> promoter region ofHBD-2 contains four NF-jB binding sites [4]. Weobserved that LPS led to increased NF-jB levels in the< /b> nucleus and decreased NF-jB levels in the < /b> cytoplasm.However, the...