Báo cáo khoa học: Mechanisms of obesity and related pathologies: The macro- and microcirculation of adipose tissue pdf

... differentiation and adipose tissue expansion, hypoxia-induced neovascularization, and the relation- ship of adipose tissue with lymphatic circulation. Adipose tissue Adipose tissue depots and obesity Obesity ... in elucidating the key systemic and local effects of adipose tissue [1]. Many of these topics are now areas of intense research and have fu...

Ngày tải lên: 29/03/2014, 22:21

... from the c oils that can act as ligand binding sites. An overlap of one coil of pelC and TmAFP is shown in Fig. 4 B. The overlap emphasizes the similarity of the b-strand along the TXT face of ... [53]. Role of the TXT motif and water in activity Examination of the crystal structures of the insect AFPs also revealed the presence of an array of water mol...

Ngày tải lên: 19/02/2014, 16:20

... latter depends on (a) the structural integrity of the vascular bed of the penis; (b) the endothelium lining the cavernosal arteries and the helicine arterioles, as well as the endothelium lining the lacunar ... measurements to assess obesity and this, in addition to the age of the cohort being studied, has influenced the strength of the correlation between...

Ngày tải lên: 18/02/2014, 06:20

... cells in the form of triglycerides, leads to the development of obesity. Despite the pivotal role of obesity and dyslipide- mia in the development of the metabolic syndrome and heart disease, the functional ... [36,37]. Despite the pivotal role of obesity and dyslipidemia in the development of the metabolic syndrome and heart disease, the functiona...

Ngày tải lên: 29/03/2014, 22:21

... discussion of the recent identification of molecular mechanisms controlling the devel- opment and function of adipose tissues, as well as how these mechanisms contribute to the regulation of energy ... in a multitude of locations and consists of two major forms: white adipose tissue (WAT) and brown adipose tissue (BAT). WAT is the main site for the sto...

Ngày tải lên: 29/03/2014, 22:21

... treatment [27,28]. The identification and characterization of the molec- ular targets of DS are of prime importance in order to understand the pharmacological and ⁄ or toxicological effects of this therapeutic ... concentrations of the non-physiological reductant dithiothreitol. These data suggest that the DS-depen- dent inhibition of NAT1 is unlikely to be a result...

Ngày tải lên: 07/03/2014, 02:20

... presence of 6.4 nmol lysoPtdIns and 6.4 nmol lysoPtdCho. Results Fatty acid composition of phospholipids from tissues of yellowtail and rat The fatty acid compositions of PtdCho, PtdEtn, PtdSer and PtdIns ... abundant. In both the PtdEtn and PtdSer fractions, docosahexaenoic acid was the predominant PUFA in all the tissues. The presence of dimethylacetals in PtdEtn...

Ngày tải lên: 08/03/2014, 08:20

... information required for the molecular recognition and self-assembly mediating the formation of amyloid fibrils. The small size of the peptides has reduced the complexity of the amyloid formation ... addition to the five in normal prion protein (PrP) [28]. The role of the peptide repeats in the aggregation of yeast prion proteins was demonstra- ted by the obser...

Ngày tải lên: 23/03/2014, 11:20

... our understanding of the importance of different parts of the molecule and their flexibility in the process of amy- loid fibril formation often results more from a struc- tural analysis of the amyloid ... with those of Sanders et al. [155]. On the basis of thermodynamic and kinetic data, they concluded that oligomerization of the chicken cystatin occurred in the...

Ngày tải lên: 14/02/2014, 18:20

... and 482) and one Thr residue (amino acid 487) were well conserved in the KIND2 of v-KIND in all species analyzed, although not in the other KINDs. To investigate the possible involvement of these ... downstream of v-KIND overexpression [12]) enhances the activity of MAP2 to bind to microtubules and promote their assembly [18], and that the inhibition of JNK1 (such...

Ngày tải lên: 14/02/2014, 19:20