Báo cáo khoa học: Mechanisms of obesity and related pathologies: Transcriptional control of adipose tissue development pdf
Báo cáo khoa học: Mechanisms of obesity and related pathologies: Transcriptional control of adipose tissue development pdf
... MINIREVIEW
Mechanisms of obesity and related pathologies:
Transcriptional control of adipose tissue development
Cecile Vernochet, Sidney B. Peres and Stephen R. Farmer
Department of Biochemistry, ... directing the formation of WAT and BAT during
development. The most notable of these adipogenic
effectors are members of the BMP family of transform-
Contr...
Tài liệu Báo cáo khoa học: Hypothalamic malonyl-CoA and CPT1c in the treatment of obesity pptx
... MINIREVIEW
Hypothalamic malonyl-CoA and CPT1c in the treatment
of obesity
Michael J. Wolfgang and M. Daniel Lane
Department of Biological Chemistry, The Johns Hopkins University School of Medicine, Baltimore, ... entry of fatty acid into mitochon-
dria. Thus, the steady-state level of malonyl-CoA in
these tissues is determined by the relative activities of
ACC and malonyl-...
Tài liệu Báo cáo khoa học: Toggle switches, pulses and oscillations are intrinsic properties of the Src activation/deactivation cycle doc
... 6. Control of the period and amplitude of Src oscillations by
the activities of the activatory phosphatase RPTP and inhibitory
kinase Csk. Dependence of the oscillation amplitude (A) and period
(B) ... coexistence of oscillations (limit cycle) and a stable
steady state implies subcritical Hopf bifurcation and
the appearance of an unstable limit cycle. The unstable
and...
Tài liệu Báo cáo khóa học: Active-site residues and amino acid specificity of the bacterial 4¢-phosphopantothenoylcysteine synthetase CoaB pptx
... is also cofactor of
enzymes that catalyze the biosynthesis of polypeptide
antibiotics [1]. Lipmann discovered and characterized
coenzyme A [2] and Lynen elucidated that the thiol
group of the cysteamine ... described
[5].
Purification and characterization of Dfp and CoaB
proteins
Growth of strains. E. coli M15 (pREP4, pQE8/pQE12)
cells were grown in the presence of ampicill...
Tài liệu Báo cáo khoa học: Second messenger function and the structure–activity relationship of cyclic adenosine diphosphoribose (cADPR) doc
... found
in various cell types, tissues and organisms. Receptor-mediated formation
of cADPR may proceed via transmembrane shuttling of the substrate
NAD and involvement of the ectoenzyme CD38, or ... function and the structure–activity
relationship of cyclic adenosine diphosphoribose (cADPR)
Andreas H. Guse
University Medical Center Hamburg-Eppendorf, Center of Experimental Medic...
Báo cáo khoa học: A new molecular tool for transgenic diatoms Control of mRNA and protein biosynthesis by an inducible promoter–terminator cassette docx
... completely shut off, the expression of
genes that are under control of the Pnr ⁄ Tnr cassette.
Decoupling of transcription and translation
of gfp mRNA
To further evaluate the properties of the Pnr ... addition of both nitrate and appro-
priate concentrations of ammonium allows, within lim-
its, the control of the amount of induced protein. The
observed lag phase of...
Báo cáo khoa học: Proteoglycans in health and disease: the multiple roles of syndecan shedding ppt
... antitumour effect
[22].
Tissue inhibitor of metalloproteinases
The catalytic activity of MMPs can be inhibited by the
family of tissue inhibitor of metalloproteinases
(TIMP), of which there are four ... SA, Copeland RA,
Decicco CP, Wynn R et al. (1999) Purification and
cloning of aggrecanase-1: a member of the ADAMTS
family of proteins. Science
284, 1664–1666.
53 Echterme...
Báo cáo khoa học: Amino acid biosynthesis and metabolic flux profiling of Pichia pastoris ppt
... State
University of New York, the Spanish Ministry of Science and
Technology (CICYT project PPQ2001-1908), and the Academy of
Finland (projects 52311 and 202409). The authors thank J. M. Cregg
and C. Gancedo ... arising
from the action of the glyoxylate cycle and the efflux of
oxaloacetate (OAA) from the mitochondria cannot be
distinguished [18]. Hence, the exchange of OA...
Báo cáo khoa học: Akt-dependent phosphorylation negatively regulates the transcriptional activity of dHAND by inhibiting the DNA binding activity pdf
... the transcriptional activity of dHAND-
Asp-X/E47 was much lesser than those of wild type. These
results indicated that phosphorylation of dHAND
decreased the transcriptional a ctivity of dHAND/E47
heterodimer.
Fig. ... Akt inhibited the
transcriptional activity of dHAND. We analyzed the
mechanisms of this inhibitory effect of Akt-dependent
phosphorylation on the transcr...
Báo cáo khoa học: Sp3 transcription factor is crucial for transcriptional activation of the human NOX4 gene doc
... survival and
tooth development [18], hematopoiesis [19] and myo-
cardial development [20]. The involvement of Sp1
and ⁄ or Sp3 in transcriptional activation is gene-spe-
cific. While both Sp1 and Sp3 ... activity of
NOX4 is regulated by the level of mRNA [10]. Thus,
the expression level of NOX4 seems to be directly
linked to its enzymatic activity. The mechanisms of...