... for the initial analysis. The sequenceswere compared against the V$SP1_Q2_01 TRANSFACposition weight matrix of Sp1 target motifs with a core cut-off of 0.90 and a similarity matrix cut-off of ... activity of the p73 P1 promoter.Finally, it is also possible that the influence of Sp1 onDMp73 levels might be the combinational and ⁄ or syn-ergistic result of all the above-mentioned processes.Therefore, ... numerous isoforms as a result of: (a) alternativesplicing in the 3¢-end (leading to the formation of a, b,c, d, e, f and g isoforms) [8–12]; (b) the use of anextrinsic promoter (P1) and an alternative,...