... different protein folds could have evolved from each other and developed anew. It fur- ther shows the potential of this concept for the design of new proteins from folding fragments where each fragment ... please view Abstract Addendum I62 Implication of extracellular matrix in growth and metastatic potential of human breast cancer cells to bone: the role of zoledronate N. Karamanos 1 ,P.Dede...
Ngày tải lên: 06/03/2014, 11:20
... pathway provides insights into the hypoxic signaling response of ECs, and identifies PAR-2 as a potential target in hypoxia-driven tumor angiogenesis. B2.61 In vitro growth inhibitory effects ... expression of TG2 was highly increased and contributed to the expression of GP91phox. Our working hypothesis is that TG2 could perform these distinct functions through its cross linking activity and/o...
Ngày tải lên: 06/03/2014, 11:20
Báo cáo khoa học: Evaluation of potential regulatory elements identi®ed as DNase I hypersensitive sites in the CFTR gene doc
... Evaluation of potential regulatory elements identi®ed as DNase I hypersensitive sites in the CFTR gene Marios ... identi®ed DNase I hypersensitive sites (DHS) across 400 kb ¯anking the CFTR gene in order to locate potential regulatory elements [1±5]. These DHS lie 5¢ tothegeneat)79.5 and )20.9 kb with respect ... of individual intragenic DHS in regulation of CFTR expres- sion. The ®rst series...
Ngày tải lên: 08/03/2014, 10:20
Báo cáo khoa học: Signal Transduction pot
... P-LAP/IRAP was involved in the increasing malignant potential of endometrial cancer mediated by insulin. P-LAP/IRAP was suggested to be a potential new target of molecular-targeted therapy for ... pattern was consistent with the presence of type I (III) and type V (VI) AC isoforms. Our current hypothesis is that RA induced AC-sensitization via an autocrine mechanism whereby secreted soluble ....
Ngày tải lên: 16/03/2014, 10:20
Báo cáo khoa học: Structure and potential C-terminal dimerization of a recombinant mutant of surfactant-associated protein C in chloroform/methanol ppt
... strongly. 2082 B. Luy et al.(Eur. J. Biochem. 271) Ó FEBS 2004 match the potential a-helical dimer found here. The interpretation of the potential dimeric state as the transition state to b-fibril formation ... of dimer formation during trafficking. Potential dimerization site The evidence suggests dimerization of SP-C, and it might be allowed to speculate on the potential dimerization site. Th...
Ngày tải lên: 16/03/2014, 16:20
Báo cáo khoa học: "Pipeline Iteration" potx
... for the pipeline, we may want to extract annotations with high levels of agreement (“consensus hypotheses”) between candidates. In addition, we may want to favor precision over recall to avoid ... each preterminal directly to the root of the tree, in addi- tion to rules permitting any combination of hypoth- esized base phrases. Consider the trees in Fig. 2. Figure 2(a) is a shallow parse with...
Ngày tải lên: 17/03/2014, 04:20
Báo cáo khoa học: "Translating Idioms" pot
... may undergo various syntactic operations, as exemplified in (2-3). (1)a. pomme de terre 'potato' b. ~ cause de 'because of' c. d~s lors que 'as soon as' The
Ngày tải lên: 17/03/2014, 07:20
Báo cáo khoa học: "Topological Parsing" pot
... being this extended CFG and the 284 other, an interpretive tectogrammatical tree struc- ture with potentially crossing links. Along with these come constraints that associate substructures from
Ngày tải lên: 17/03/2014, 22:20