Báo cáo khoa học: "REVERSIBLE AUTOMATA AND INDUCTION OF THE ENGLISH AUXILIARY SYSTEM" doc
Báo cáo khoa học: "REVERSIBLE AUTOMATA AND INDUCTION OF THE ENGLISH AUXILIARY SYSTEM" doc
... In this paper we apply some recent work of Angluin (1982) to the induction of the English auxiliary verb system. In general, the induction of finite automata is computation- ally intractable. ... inducing the language. Though the minimal number of examples is of course unique, the set of particular strings in the covering sample is not necesm~rily Imique. INFERENCE OF THE ENGLISH AUXILIARY ... OVERGENERALIZATION OF THE ENGLISH AUXILIARY SYSTEM bread Figure I: The top automaton generates the English auxiliary system. Zero-reversible inference merges state 3 with state 2 and merges states 7 and...
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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... expression of T-bet has beenseen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung tissue of mouse and spleen and thymus of human and mouse ... end of the gene, where the zebrafish and human sequences appearto be quite diverse. Together with the well-conservedgene organization, there is a conservation of syntenybetween the human and ... CD4+CD25+Foxp3+Tregor whetherthey induce the production of these cytokines fromanother population of cells [20].To date, our knowledge about the different types of Th and Tregresponses relates...
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Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt
... [20]. The role of SREBP-1a in the regulation of cell growth and the cell cycle might be biphasic and complex, and needs to be further investigated.SREBP is evolutionarily conserved; however, the key ... involved in the regulation of genesparticipating in cholesterol biosynthesis and low-densitylipoprotein receptor synthesis [1,2]. They are now estab-lished as global regulators of lipid synthesis. ... apparatus, where the site 1 and site 2 proteases cleave the SREBPs [3,4].Upon restoration of cellular cholesterol, Insig, anotherkey regulator of ER membrane proteins, traps and retains the SREBP–SCAP...
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Tài liệu Báo cáo khoa học: Domain deletions and substitutions in the modular protein evolution doc
... for the proteins with the complete arrangement. To take into account the variability of the length of the complete domain, the length of the N-terminal fragment was definned as the length of the amino ... number of domains in the protein and the database selected (Fig. 1). The prevalence of terminal deletions did not depend on the number of domains in proteins, and the results for Pfam and Pro-Dom ... number of domains.We found that the domain deletions are more com-mon at either of the protein termini, and that theiroccurrence is slightly higher at one of the termini,depending on the number...
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Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
... analysis of the topological modules of the Fig. 3(labelled A–G) shows that they include structural and ⁄or functional features. Table 3 summarizes the main structural and functional features of thesegroups. ... functions, and topologi-cal features retain functionality and phylogeny. How-ever, the nature of the connections between thesefactors needs to be understood at the level of the pro-tein domain. The ... of interacting proteins responsible for the control of geneexpression. They interact with DNA regions and tendto form transcriptional regulatory complexes. Thus, the final effect of one of these...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt
... comparison of the genomic and cDNAsequences. Analysis of the amino acid sequences deducedfrom the cDNA, including prediction of signal peptide and glycosylation sites, was carried out in the expasy ... proSpa¨tzle-1A is an ortho-log of the product of this gene. In the clade includingSpa¨tzle-1, the branch lengths are noticeably longer and the bootstrap values are lower than in the other cladescontaining ... proHP8Xa and the catalytic domain of active HP8 are marked with arrowheads. The size and position of molecular weight stan-dards are indicated on the left. (B) The catalytic activity of activated...
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Báo cáo khoa học: Thermodynamic stability and folding of proteins from hyperthermophilic organisms doc
... Methanother-mus and Sulfolobus) [2]. Notably, no hyperthermophiliceukaryote has yet been discovered [1].Comparisons of the thermodynamics and kinetics of the folding of proteins from mesophilic and thermo-philic ... C& Mateo P (2004) Thermodynamic analysis of the unfolding and stability of the dimeric DNA-bindingprotein HU from the hyperthermophilic eubacteriumThermotoga maritima and its E34D mutant. ... literature. For each protein, the source organism, its maximum growth temperature, the fold of the protein, the pres-ence of cofactors, the oligomeric state, and the protein databank accession...
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Báo cáo khoa học: Purification and characterization of the cysteine proteinases in the latex of Vasconcellea spp. ppt
... content in their latex; and (2) the pres-ence of other cysteine proteinases or isoforms in the latex. To investigate these two hypotheses, the proteinconcentration per milligram of dried latex, ... Fractionation and purification of the enzymes stored in the latex of Carica papaya.J Chrom B 790, 229–238.32 Laemmli UK (1970) Cleavage of structural proteinsduring the assembly of the head of bacteriophage ... the other sequences. The MP tree reveals threemajor clusters. Cluster I combines the five chymo-papain isoforms of C. papaya with VXH-C, VS-B,CC-III and CC23. These results confirm the hypothesisof...
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Báo cáo khoa học: Identification and characterization of plasma kallikrein–kinin system inhibitors from salivary glands of the blood-sucking insect Triatoma infestans pptx
... [55].Expression and purification of the recombinantN-terminal region of FXII and domain D5 of HKExpression vectors for the recombinant N-terminal region of FXII and domain D5 of HK were constructed ... endothelial cell surface, and isthen accelerated by the reciprocal activation of FXII and PK on the surface. Zn2+is essential for binding of FXII and HK to a biological activating surface, and ... interferencewith the binding of FXII and HK to activating sur-faces. Furthermore, triafestin-1 and triafestin-2 specif-ically interacted with the N-terminal region of FXII and domain D5 of HK, which are the...
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Báo cáo khoa học: Identification and expression of the first nonmammalian amyloid-b precursor-like protein APLP2 in the amphibian Xenopus laevis ppt
... in the brain and further displays anumber of structural features not present in the othermembers of the APP superfamily, such as the absence of the exon encoding the KPI domain and the lack of ... in the appearance of the APLP1 and APLP2gene families. The fact that both mammals and Xenopuscontain APP and APLP2 proteins suggests that the firstgene duplication giving rise to the APP and ... analysis of the APP superfamilyTo reveal the evolutionary history of the APP superfamily,we used maximum likelihood and Bayesian methods toconstruct a phylogenetic tree of the members of the APPsuperfamily...
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