Báo cáo khoa học: Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase pdf

... exons of exons 1a and 1c contributed to the 5¢ nontranslated region of isoform 1 mRNA in which the common exon 2 contains an initiation codon. Intronic 5¢ consensus GT was located adjacent to the 3¢ ... determining their transcription initiation sites. Exon 1b con- tained the initiation codon of isoform 2, and noncoding exons 1a and 1c contributed to isoform 1 mRNA. The...

Ngày tải lên: 19/02/2014, 06:20

... make the predictions. In the first case, predictions of the pleasantness of stereotype nouns based on the pleasantness of their salient properties (i.e., predicting the pleasantness of Y from the ... the scale of the Bard’s genera- tivity, and the quality of its insights. 5 Empirical Evaluation The vastness of the web, captured in the large- scale sam...

Ngày tải lên: 20/02/2014, 05:20

... attention. The general architecture of the NPC is evolutionarily con- served in all eukaryotes and consists of filaments on the cytoplasmic surface and spoke rings and a basket- like structure on the ... Ran. Con- versely, the concentration of RanGDP is high in the cytoplasm as a result of the action of RanGAP, which promotes cytoplasmic GTP hydrolysis by Ran...

Ngày tải lên: 06/03/2014, 01:20

... S5), and indicate that BACE1 is responsible for the generation of at least  20% of APLP2s. BACE1 manipulation alters the quantity and form of APP, APLP1 and APLP2 CTFs To examine the effects of ... BACE1 on the processing of the APP family of proteins. BACE1 expression regulated the levels and species of full-length APLP1, APP and APLP2, of their she...

Ngày tải lên: 15/03/2014, 10:20

... how the phosphorylation of different parts of the CTD contributes to these functions. At least three protein kinases are involved directly in the phosphorylation of the CTD and in the regulation ... only, but the hyper- phosphorylated IIo form was not produced [28]. The authors conclude that the hyperphosphorylation, and the production of the IIo form of pol...

Ngày tải lên: 23/03/2014, 12:20

... decreased by the deletion of GC-box1. The activity was further decreased by the deletion of GC-box2 (Fig. 3B). As shown in Fig. 3C, the transcriptional activity of the 1 kb of the 5¢-flanking region was ... by the deletion of GC-box3, the GC-rich Fig. 1. Alignment of the 5¢-nucleotide sequences of the human, rat and mouse NOX4 genes. The numbers on the...

Ngày tải lên: 29/03/2014, 00:20

... 1995) computes the F1 score (harmonic mean) of preci- sion and recall based on the identifcation of unique coreference links. We use the of cial MUC scorer implementation for the two MUC corpora and an equivalent ... measures the impact of each resolution class on the overall MUC score. 4.3 Results Table 4 shows the results of our resolution class analysis on...

Ngày tải lên: 30/03/2014, 23:20

... Temperature and salts effects on the peptidase activities of the recombinant metallooligopeptidases neurolysin and thimet oligopeptidase Vitor Oliveira 1 , Reynaldo ... TDS Ã ð3Þ Dependence of the hydrolysis reaction rates by neurolysisn and TOP on concentration and chemical nature of salts The dependence of the rate constants according to...

Ngày tải lên: 23/03/2014, 21:21

... Particular attention is paid to the effects of temperature on enzyme allostery and the influence of temperature in the regulation of PFK activity at both high (euthermic) and low (hibernating) temperatures. Results Selected ... shows the effect of temperature on activation coefficient (K a ) values for allosteric activators and the values of concentration...

Ngày tải lên: 19/02/2014, 16:20

... the rate of C-H bond-breaking is a major factor in determining the rates of the reactions under all conditions. Some shift- ing of the oxidations to the alternate 3-hydroxylation reactions occurs ... steps involved in the generation of the reactive oxygen species, as opposed to the reactions of the activated complex with substrates, in light of the low endogeno...

Ngày tải lên: 16/03/2014, 13:20