Báo cáo khoa học: In vitro and in vivo self-cleavage of Streptococcus pneumoniae signal peptidase I pot

... SDS/PAGE. In vitro self-cleavage of S. pneumoniae SPase I For in vitro self-cleavage of S. pneumoniae SPase I in the presence of phospholipid, 20 lL of reaction containing 5 lg of purified SPase I was incubated ... In vitro and in vivo self-cleavage of Streptococcus pneumoniae signal peptidase I Feng Zheng, Eddie L. Angleton, Jin Lu an...

Ngày tải lên: 23/03/2014, 21:21

... relative activities of OAT:OAE-L provides a significant insight into the regula- tion of this important modification in normal as well as in diseased tissue. Based on this information a reduction in ... reduced in comparison with that observed in Stage I, II and III patients. This suggests that not only is sialic acid O-acetylation decreased in the tumour itself but also in...

Ngày tải lên: 07/03/2014, 14:20

... 10 4 0.6 0.65 0.7 0.75 0.8 0.85 0.9 performance dimensionality lqword chi-tfidf chi-tfidfcig chicig-tfidf chicig-tfidfcig 1 2 3 4 5 6 7 x 10 4 0.6 0.65 0.7 0.75 0.8 0.85 0.9 dimensionality bigram chi-tfidf chi-tfidfcig chicig-tfidf chicig-tfidfcig ... 10 4 0.5 0.6 0.7 0.8 lqword performance chi-tfidf chicig-tfidfcig 1 2 3 4 5 6 7 8 x 10 4 0.5 0.6 0.7 0.8 bigram performance dimensional...

Ngày tải lên: 08/03/2014, 02:21

... KNOI~LEDGE ORGANIZATION AND APPLICATION: BRIEF COMIIENTS ON PAPERS IN THE SESSION Aravind K. Joshi Department of Computer and Information Science The Moore School University of Pennsylvania, ... representation. It is concerned with complete and partial matching procedures, especially for determining whether a particular instance satisfies the criteria for membership in a...

Ngày tải lên: 31/03/2014, 17:20

... inter- mediate of protein is observed. In comparison, the unfolding of FprA by guanidinium chloride proceeds through intermediates that are stabilized by interaction of protein with guanidinium chloride. ... The NADPH-binding domain of FprA was found to be sensitive to cations, which induce significant destabil- ization of this structural domain. Furthermore, modu- lation of ioni...

Ngày tải lên: 19/02/2014, 16:20

... but increases the activity of the Zn 2+ -containing APase [3,4]. Significant cooperative inter- actions have been detected during metal-ion binding, positive for the binding of Zn 2+ to the M1 site, ... Mg 2+ concentration, is probably due to Mg 2+ binding to the zinc binding sites (M2 and M1). It appears that in contrast to the binding of Zn 2+ to the second M3 site, Mg 2+ binding...

Ngày tải lên: 21/02/2014, 00:20

... rather than with the PAS domain, these data suggest a multiligand regulation of PASKIN activity, including a still unknown PAS domain binding ⁄ activating ligand and kinase domain bind- ing modulatory ... might be involved in insulin regulation in the pancreas. According to the current model, binding of a putative ligand to the PAS domain disinhibits the kinase domain, lead- ing to...

Ngày tải lên: 06/03/2014, 00:21

... unwinding, (b) inhibition of ATP hydrolysis or release of ADP by blocking opening or closing of domain 2, (c) inhibition of RNA (or DNA) substrate binding, (d) inhibition of unwinding by sterically ... comparison of ATP-binding sites, indicated that, unlike the case with casein kinase 2, the mode of action of the inhibitors vs the helicases is not by interaction with the cata...

Ngày tải lên: 08/03/2014, 02:20

... syntactic positions where they are foreign to the semantic distributions, among them are ralsmg operations, which induce distributional differences such as I imagined the situation I imagined ... considered as auxiliaries. The predicative element is here the nominal form in complement position. This intuition can be given a formal basis. Let us look at nominalizationa as being rel...

Ngày tải lên: 08/03/2014, 18:20

... muta- tion in the tail domain of dynein causes increased flexi- bility of the dynein molecule and diminished gating between the motor domains [94]. H. Sakakibara and K. Oiwa Dynein structure and its ... compilation ª 2011 FEBS 2979 MINIREVIEW Molecular organization and force-generating mechanism of dynein Hitoshi Sakakibara 1 and Kazuhiro Oiwa 1,2 1 National Institute of In...

Ngày tải lên: 14/03/2014, 22:20