Báo cáo Y học: Thermolysin-linearized microcin J25 retains the structured core of the native macrocyclic peptide and displays antimicrobial activity doc

... J. Biochem. 269) Ó FEBS 2002 Thermolysin-linearized microcin J25 retains the structured core of the native macrocyclic peptide and displays antimicrobial activity Alain Blond 1 , Michel Cheminant 1 , ... very well defined, stabilized primarily by the hydrogen bonds of a tightly packed b-sheet. In this study, we examined the solution structure, stability,...

Ngày tải lên: 23/03/2014, 21:20

... puri®ed and the gene encoding the enzyme has been cloned and sequenced. The enzyme was rapidly and irre- versibly inactivated by sodium borohydride o r h ydroxyl- amine in the presence of propionyl-CoA. ... spect- rometry [14]. Alternatively the mixed anhydride interme- diates can be detected by the formation of stable derivatives of the catalytic glutamate and hyd...

Ngày tải lên: 17/03/2014, 17:20

... satisfaction with the duration of effect of the study medication on their child's ADHD symptoms. Regarding medication satisfaction with tolerability of MTS, at study endpoint the majority of caregivers ... that the study medication decreased their child's appetite. The majority of caregivers (88.1%) disagreed that the study medication made their child feel slee...

Ngày tải lên: 25/10/2012, 10:06

... pregnancy of a healthy 24-year-old mother. They have no family history of genetic diseases. Both had Apgar scores of 9/9 at 1 minute and 9/9 at 5 minutes. The placenta was examined and described ... pathogenesis of AC. The findings in our case indicate that early neuroimaging is mandatory in the counterpart of the sympto- matic patient with AC, irrespective of th...

Ngày tải lên: 25/10/2012, 11:00

... the sensitivity of 92.85% and the specificity of 91.25%. Blind test data indicated a sensitivity of 86.95% and a specificity of 85%. The result suggested that MALDI technology could be used ... Analysis of Serum Samples in Patients with CRC and Healthy Controls The protein profile of the serum samples from the 98 patients with CRC and the 80 healthy contro...

Ngày tải lên: 25/10/2012, 11:18

... title.) Theoretical framework Theoretical frameworks underpinning this study include Marilyn Ray’s Theory of Bureaucratic Caring, later augmented by Turkel in the development of the Theory of ... en- terprise system of healthcare. The authors plan to replicate this study among Directors and Deputy Di- rectors of nursing in Great Britain’s Socialist system of healthc...

Ngày tải lên: 26/10/2012, 08:57

... PHC data of the statements made by the mid-wife in her records of the check-up of the mothers during the pregnancy (17). In the follow-up at the age of seven, n= 191 children of the defined ... U, Anderson HR, Burney P. Comparison of asthma prevalence in the ISAAC and the ECRHS. ISAAC Steering Committee and the European Community Respiratory Health Su...

Ngày tải lên: 26/10/2012, 09:48

... diagnosis of cancer. In summary, the Gab1 A/A was associated with the low risk of H. pylori infection while the G/A and A/A genotypes together may increase the risk for gastric atrophy. The biological ... shows the age-sex-adjusted ORs of the Gab1 and the combinations of PTPN11 and Gab1 genotypes for gastric atrophy among seropositive healthy controls. Th...

Ngày tải lên: 31/10/2012, 15:37

... prepared and analysed as described in A. The molecular weight and position of the two forms of antizyme is indicated on the right. *NS indicates the position of nonspecific proteins recognized by the ... antizyme was rapidly degraded in both the presence and the absence of coexpressed ODC (Figs 2C and D). Similarly, we have noted that antizyme that was induced by...

Ngày tải lên: 22/02/2014, 04:20

... to that of free VIIa–TF, which is also an evidence of the hypothesis. Fig. 5. Verification of the hypotheses for TFPI inhibitory mechanism. (A) Verification of the hypothesis of the enzyme–product ... Xa–VIIa–TF complex. To test the ability of the hypothesis to describe these experiments accurately, the enzyme–product stage must be added to the model of the study...

Ngày tải lên: 22/02/2014, 04:20