Báo cáo khoa học: Complex alternative splicing of the hKLK3 gene coding for the tumor marker PSA (prostate-specific-antigen) ppt

... Complex alternative splicing of the hKLK3 gene coding for the tumor marker PSA (prostate-specific-antigen) Nathalie Heuze ´ -Vourc’h, Vale ´ rie ... that some of the free forms are produced by proteolysis of proPSA [13] or mature PSA [14]. Some of the others could be produced by alternative splicing [15]. Alternative splicing is the most wide...

Ngày tải lên: 23/03/2014, 20:22

... conditions during the complex formation [6]. In general, increasing the saturation of the column with oleic acid resulted in the formation of ELOA with a higher oleic acid content. The number of equine ... HAM- LET-like complexes depends on the method of produc- tion [27]. The stoichiometry of oleic acid in the complexes probably significantly modifies the mecha- n...

Ngày tải lên: 29/03/2014, 21:20

... the nonterminal symbols being rewritten. The linear version of the formalism allows the full index infor- mation from the parent to be used to specify the index information for only one of ... exactly to the hi- erarchical structure that the derivation imposes on the str!ng, the derived tree structure of the string. The formalism of tree-adjoining gram...

Ngày tải lên: 20/02/2014, 21:20

... are generated through other modifications of the side chain or of the A-ring [12]. Cytochrome P450scc (CYP11A1) catalyzes the first step in steroid synthesis, the cleavage of the side chain of cholesterol ... killed under anesthesia. The animals were housed at the vivarium of the Department of Biotestings of Bio- organic Chemistry Institute, Minsk, Belarus. The e...

Ngày tải lên: 23/03/2014, 10:21

... be expected to have the largest effect on the expansion of the cavity. On the other hand, the size of the side-chain of the amino acid residue used to substitute for serine 140 of S. solfataricus ... by the acquisi- tion of a characteristic amino acid residue at the second position before the G(Q/E) motif supports this hypothesis. Discussion The importance o...

Ngày tải lên: 23/03/2014, 17:21

... only of p init to the stack consisting only of p final . The computed output consists of the string of terminals b 1 · · · b n  from the output components of the applied transitions. For the PDTs ... cubic in the length of the input. Otherwise, the time complexity would be O(n m+1 ), where m is the length of the longest right-hand side of a rule in the...

Ngày tải lên: 31/03/2014, 03:20

... modi- fied to perform an assay measuring the effect of compe- tition of a ten-fold excess of XMP on the GTPase activities of the native protein and the TorD D68N vari- ant. The GTPase activity of TorD D68N was ... [29,30]. To determine the requirement for magnesium of the GTPase activity of TorD, the reaction was performed in varying amounts of MgCl 2 (Fig. 1B...

Ngày tải lên: 16/02/2014, 09:20

... each other). The value (the sign) of a cycle is the product of the values (the signs) of its steps. The sign o f the magnitude of a Ôminus combined autoinfluence path of order pÕ equal those of the ... The absolute magnitude of a combined autoinfluence path is the product of all the rates divided by the product of all the concentrations of its species...

Ngày tải lên: 19/02/2014, 16:20

... to the values previously found for high spin Mn(III) complexes of Mn superoxide dismutase [28] and the fluoride derivative of WT LPC [27]. On the other hand, the value found for the high pH form ... atoms. Even in the region of the mutation, the basic fold of the WT protein is preserved, but the deletion of the hydroxyl group in the aromatic side chain on...

Ngày tải lên: 08/03/2014, 08:20

... asked the question whether we can inhibit expres- sion of the gene of BACE protein using our engineered ribozymes. In order to check the potential of plasmid coded ribozymes for cleavage of the ... 5¢-ACUACAAAAACCAAC-3¢ sequence, which prevents the processing of the 3¢-end of the transcript and secures cloverleaf secondary structure of the tRNA motif. Extensi...

Ngày tải lên: 08/03/2014, 08:20