Báo cáo khoa học: Secretion of pigment epithelium-derived factor doc

... Biochem. 270) 831 Secretion of pigment epithelium-derived factor Mutagenic study Hanshuang Shao, Iris Schvartz and Shmuel Shaltiel* Department of Biological Regulation, Weizmann Institute of Science, ... activity; pigment epithelium-derived factor (PEDF); secretion; serpin. Pigment epithelium-derived factor (PEDF) was originally identified as an extracellular compone...

Ngày tải lên: 23/03/2014, 20:22

... Sweden; 2 Department of Biochemistry, Institute of Medical Biology, University of Tromsø, Norway; 3 Department of Biochemistry, University of Oslo, Norway; 4 Institute for Molecular Science of Medicine, ... Western blot is the inactive proform of uPA. It is possible that the effect of HX-xyl could be mediated through increased secretion of PAI-1. A decreased activity of...

Ngày tải lên: 08/03/2014, 08:20

... direct colocalization of GFP-EEA1-(FYVE) 2 with p45. M. Merkulova et al. Secretion of p45 Sec14p-like protein FEBS Journal 272 (2005) 5595–5605 ª 2005 FEBS 5599 A B E C D Secretion of p45 Sec14p-like ... and therefore cannot colocalize with p45. Fig. 3. Secretion of the SEC14 domain of p45. (A) The hydrophilicity plot of p45 protein and location of the SEC14 and GOLD domai...

Ngày tải lên: 16/03/2014, 23:20

... Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Norway 2 Department of Molecular Biosciences, University of Oslo, Norway 3 Department of Biochemistry, Institute of Medical ... level of HisTrap isolated 35 S-labelled sergly- cin, and amount of serglycin core protein as detected by western blotting, also showed the highest secretion of pro...

Ngày tải lên: 30/03/2014, 11:20

... FEBS tion of China (30900623), and the Doctoral Fund of Ministry of Education of China (Fund for New Teacher, 20090162120020). References 1 Dang DT, Pevsner J & Yang VW (2000) The biology of the ... KLF4-induced enhance- ment of the expression of the tumour suppressor gene p53 [5]. Because of the important roles of KLF4 on the above three cell types, we postulated the no...

Ngày tải lên: 18/02/2014, 04:20

... the inhibitory Smad7 protein and the RhoB gene. Activation of cofactors such as serum response factor, AP1, GATA and myosin enhancer factor 2 via p38 MAPK or other pathways facilitates these transcriptional ... transcriptional upregulation of smooth muscle-specific genes such as a-SMA, SM-MHC and SM-22a via the cooperation of serum response factor, GATA and myosin enhancer factor 2...

Ngày tải lên: 07/03/2014, 01:20

... School of Biological Sciences, Faculty of Science, University of Auckland, New Zealand 2 Department of Pharmacology and Clinical Pharmacology, Faculty of Medical and Health Sciences, University of ... characterisation of the human insulinoma cell line CM. J Endocrinol 161, 59–68. 47 Stadheim TA, Saluta GR & Kucera GL (2000) Role of c-Jun N-terminal kinase ⁄ p38 stress sign...

Ngày tải lên: 07/03/2014, 12:20

... Section of Oncopathology and Regenerative Biology, Department of Pathology, Faculty of Medicine, University of Miyazaki, Japan 2 Department of Urology, Faculty of Medicine, University of Miyazaki, ... concentration of 1 mm, and this was followed by the addition of 100 ng of each KLK. The final volume of each mixture was 150 lL. The enzymatic activity was monitored by the...

Ngày tải lên: 23/03/2014, 07:20

... important indication of effective burial of hydrophobic residues upon folding, with the formation of a r elatively compact struc- ture. This, in turn, can be promoted by a Ôcrosse dÕ disulfide topology of the ... bars) of backbone NH chemical shifts (p.p.m.) for f5b (A) and f6b (B). The distribution of backbone NH chemical shifts of EGF-14 (gray bars) and that e xpected f or a ra...

Ngày tải lên: 23/03/2014, 13:20

Ngày tải lên: 23/03/2014, 17:20