Báo cáo khoa học: Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system pot

... Presence of melanocortin (MC4) receptor in spiny dogfish suggests an ancient vertebrate origin of central melanocortin system Aneta Ringholm 1 , Janis Klovins 1 , Robert Fredriksson 1 , ... char- acterization and tissue distribution of a melanocortin (MC) receptor gene in a shark, the spiny dogfish (Squalus acanth- ias) (Sac). Phylogenetic analysi...

Ngày tải lên: 23/03/2014, 20:22

... mechanisms involved in acquired thermotol- erance in plants. Transcriptome profiling revealed 57 transcripts specifically upregulated in acclimated plants, including heat shock proteins, transcription factors ... exposure depending on the time of day of the exposure [51]. Cold induction of CBF2 involves multiple cis-acting regulatory elements, one of which binds members of the c...

Ngày tải lên: 18/02/2014, 11:20

... enabled by quantitative PCR of key metabolic enzymes including uncoupling protein 2 (UCP2) and fatty acid translocase (CD36). DNA microarray analysis of gene expression changes in exercise-induced cardiac ... exercise-induced hypertrophy was accompanied by a marked upregula- tion of genes involved in extracellular matrix remode- ling (biglycan, matrix gla protein, cathepsins, cystat...

Ngày tải lên: 23/03/2014, 13:20

... determined using 25 n M [ 3 H]PonA and increasing amounts of proteins in individual incubations. The percentage of specific b inding increased in a protein concentration-dependent manner within the range of ... the binding activities for [ 3 H]PonA in the detergent-rich phase, indicating that the mEcR is an integral membrane protein which might be anchored in the membrane by tr...

Ngày tải lên: 30/03/2014, 15:20

... neuropeptide Y and agouti related peptide in hypo- thalamic malonyl-CoA while promoting an increase in proopiomelanocortin and cocaine and amphetamine regulated transcript. Taken together, these findings provide ... plays a key role in maintaining energy balance [1–4]. In more advanced, mammalian systems there is compelling evidence for the control of energy metabolism via the cen...

Ngày tải lên: 14/02/2014, 22:20

... FEBS bean and soybean. When binding of arginine in the presence of tRNA was investigated, some changes in the binding architecture were observed [35], in that N(153:Y), in addition to interacting ... December 2008) doi:10.1111/j.1742-4658.2009.06866.x l-Canavanine occurs as a toxic non-protein amino acid in more than 1500 leguminous plants. One mechanism of its toxicity is i...

Ngày tải lên: 18/02/2014, 13:20

... first-order kinetics, was assayed in the absence of protein. In vitro interaction of HupUV and HupT The proteins (50 pmol HupUV and 250 pmol HupT) were incubated for 10 min at 30 °C in buffer containing ... proteins were introduced into the vessel, and the changes in D 2 ,HD and H 2 were monitored by scanning masses 4, 3 and 2, Table 3. Bacterial strains and plasmids used in this...

Ngày tải lên: 20/02/2014, 01:20

... actual utterance, and with perfect expression. (B) No lacking in meaning, but with slightly awkward expression. (C) Slightly lacking in meaning. (D) Considerably lacking in meaning. (E) Unable ... such errors. In integrating recognition and translation into a speech translation system, the development of the following processes is therefore important: (1) detection of err...

Ngày tải lên: 20/02/2014, 18:20

... mapping between elements of the set of substrings of the string and elements of the set of subtrees of the tree : such a relation is called a string- tree correspondence. An example of a string-tree ... processing (say for translation into another language), where all and only the relevant conten~.s or 'meaning' (in some sense adequate for the purpo- se) of t...

Ngày tải lên: 22/02/2014, 10:20

... Tissue-specific expression of mast cell granule serine proteinases and their role in inflammation in the lung and gut. Immunol- ogy 105, 375–390. 5 Caughey G (2001) New developments in the genetics and activation of ... electron-dense secretory granules, and these granules are released following MC activation, a pro- cess that can be accomplished by various mechanisms, including antig...

Ngày tải lên: 07/03/2014, 11:20