Báo cáo khoa học: "Computational Modeling of Human Language Acquisition" ppt

Ngày tải lên: 23/03/2014, 17:20

... the C-terminal half of PacC [16]. A human ortholog of PalA, ALIX (also known as AIP1), functions in the budding of enveloped RNA viruses from plasma Y. Osako et al. Enhancement of calpain 7 autolysis ... localization of calpain 7. As shown in Fig. 9A, overexpression of FLAG–IST1 did not enhance the autolysis of mGFP–calpain 7 in cultured cells. On the other hand, overexpressio...

Ngày tải lên: 18/02/2014, 04:20

... Structures of thymidine kinase 1 of human and mycoplasmic origin. Proc Natl Acad Sci USA 101, 17970–17975. 15 Sabini E, Ort S, Monnerjahn C, Konrad M & Lavie A (2003) Structure of human dCK ... B (2004) Effect of valine 106 on structure–function rela- tion of cytosolic human thymidine kinase. Kinetic prop- erties and oligomerization pattern of nine substitution mutants...

Ngày tải lên: 18/02/2014, 12:20

... small amounts of HMG-CoA and large amounts of free CoA. Peak 4 produced HMG-CoA and also large amounts of free CoA. Peak 5 produced large amounts of HMG-CoA, but also free CoA. Human 3-methylglutaconyl-CoA ... The production of (Z)-3-MG-5-CoA by Gct is probably due to the possible trans-conformation of the 5-carboxyl group of (Z)-3-methylglutaconate. Table 2. Kinetic constants...

Ngày tải lên: 19/02/2014, 07:20

... the mechanism of action of chymotrypsin: the role of the low barrier hydrogen bond. Biochemistry 36, 4576–4584. 46. Warshel, A. (1998) Electrostatic origin of the catalytic power of enzymes and the role of ... general features of the recently determined X-ray structure of human BuChE [7,8]. In particular, most of the essential features of the catalytic site (i.e. a catal...

Ngày tải lên: 20/02/2014, 23:20

... protein-coupled receptors (GPCR) represent one of the largest families of genes in the human genome. They are responsible for the detection of a large variety of stimuli and control many physiological ... Strange 1 1 School of Animal and Microbial Sciences, University of Reading, Reading, UK; 2 GlaxoSmithKline, New Frontiers Science Park, Harlow, UK Human D 2Long (D 2L )andD 2...

Ngày tải lên: 21/02/2014, 00:20

... conformation of ETNF-6 mAb Sequencing of the cDNA of the variable region of ETNF-6 mAb was performed, and this was followed by molecular modeling of its three-dimensional struc- ture. The heavy chain of ... the Ser5-Arg6 bond of TNF-a at the first step, resulting in the generation of a fragment of  17 kDa. This fragment was digested to a smaller molecule of 15 kDa by sci...

Ngày tải lên: 06/03/2014, 22:21

... H64Q mutant of Ngb was followed by measuring the decrease in intensity of the Soret band (Ngb, k max of 412 nm; H64Q, k max of 406 nm; Mb, k max of 409 nm) in the absorption spectra of the proteins, ... by proton- ation of amino acid side chains. The amino acid sequence of human Ngb, with respect to the acid-labile horse and human Mbs, displays a high degree of sub- stit...

Ngày tải lên: 07/03/2014, 02:20

... stable overexpression of any of the human spermine oxidase isoforms in human tumor cells. Furthermore, we report the first direct visualization of the localization of human spermine oxidase in a human tumor ... combination of the human isoforms 1 and 4, had been identified. The dis- covery of its existence in the mouse suggested the like- lihood of a human homologue, a...

Ngày tải lên: 07/03/2014, 05:20

... summa- tion of the elution profiles of the isolated 3D mutant of Hsp27 and isolated wild-type Hsp20 is presented on curve 1. Experimental elution profiles of the mixture of the 3D mutant of Hsp27 ... L of E. coli culture. As in the case with Hsp20, all stages of Hsp27 purification were performed in the absence of urea or detergents. Oligomeric state of recombinant human Hsp...

Ngày tải lên: 07/03/2014, 15:20