... role in aging, both by producing intracellu-lar reactive oxygen species (ROS) and by being themost adversely affected organelles during aging [3].The electron transport chain located in the inner ... increased with increasingage (27-month-old rats). Among the glycated proteins,trails of isoforms appeared, in agreement with modifi-cations targeting the basic amino acids arginine andlysine, ... defenses during aging and in response to food restriction in the mouse. Mech AgingDev 74, 121–133.7 Martinez M, Hernandez AI, Martinez N & FerrandizML (1996) Age-related increase in oxidized...