Báo cáo khoa học: Expression of heme oxygenase-1 is repressed by interferon-c and induced by hypoxia in human retinal pigment epithelial cells pot

... Expression of heme oxygenase-1 is repressed by interferon-c and induced by hypoxia in human retinal pigment epithelial cells Reiko Udono-Fujimori 1 , Kazuhiro Takahashi 1 , Kazuhisa Takeda 1 , ... geneity of R PE cells [31,48]. Effects of hypoxia on the expression of HO-1 in human RPE cell lines In contrast to interferon-c, hypoxia indu...

Ngày tải lên: 23/03/2014, 13:20

... basis of ligand recognition by PABC, a highly specific peptide- binding domain found in poly(A)-binding protein and a HECT ubiquitin ligase. EMBO J 23, 272–281. 9 Craig A (1998) Interaction of ... step in protein syn- thesis, and is usually regulated by several important initiation factors, including poly(A)-binding protein (PABP) 1 and eukaryotic initiation factors (eIFs)...

Ngày tải lên: 18/02/2014, 12:20

... simulated antagonism. The expression of agn13.2 during in vivo assays against the strawberry pathogen Botrytis cinerea strongly supports the role of AGN13.2 in the antagonistic action of T. asperellum. Results Biochemical ... carried out in liquid phases show that AGN13.2 and AGN13.1 are induced specifically by the presence of B. cinerea cell walls. Interestingly, chitin,...

Ngày tải lên: 19/02/2014, 16:20

... differences in the regulation of expression of the two genes. Gene expression during anaerobic induction The coexpression of the HydA1 and HydA2 transcripts was studied by Northern blot analysis. In Fig. ... a protein in extracts of anaerobically induced cells, which comigrated with the recombinant HydA2 protein (Fig. 4, lane 4). These results confirm that HydA2 is e...

Ngày tải lên: 20/02/2014, 11:20

... chains of the heme moiety. Interestingly, in the tryptophan to phenyalanine mutant in transmembrane helix II (W200F in Surf1c, W2009F in Surf1q), heme o is the predominant heme cofactor, indicating ... heme trans- fer in vitro by mixing purified CtaA and apo-Surf1c. Indeed, heme a is being taken up by Surf1 from its site of synthesis, CtaA, requiring a specific...

Ngày tải lên: 06/03/2014, 00:21

... erythrocytes, and the difference between acetylcholinesterases of kid- ney and erythrocytes in the extent of binding with the lectins concanavalin A, Lens culinaris agglutinin (LCA), and Ricinus communis ... proposal is in agreement with the cytochemical staining of acetylcholinesterase in the capsule of Bowman [41] and of acetylcholines- terase and butyrylcholines...

Ngày tải lên: 06/03/2014, 22:21

... regulate the expression of genes playing key r oles in the biogenesis of the OXPHOS system. In general, the transcription of nuclear genes encoding proteins involved in OXPHOS biogenesis is controlled ... belongs to a novel class of regulatory proteins, and it contains a DNA binding domain conserved in two invertebrate developmental regulators, Erect Wing and P3A2 [17]...

Ngày tải lên: 07/03/2014, 16:20

... Arabidopsis plants were selected by germinating the seeds collected from the in ltrated plants on a medium containing 50 mgÆL )1 kanamycin. Resistant T 1 plants surviving on kanamycin-containing medium ... the expression of AtZFP11 and that the phenotype of AtZFP11 could be induced by the application of ligand. In addition, the affected plants recovered after withdrawal of...

Ngày tải lên: 16/03/2014, 06:20

... in pyrimidine metabolism, as the enzyme catalyses the only reaction resulting in the amination of the pyrimidine ring into a cytosine derivative (Fig. 1). It is therefore of interest to examine ... to CTP catalyzed by CTP synthase encoded by pyrG. Involvement of pyrimidine nucleotides in synthesis of DNA, RNA, and phospholipids are indicated. Breakdown of mRNA is ind...

Ngày tải lên: 16/03/2014, 16:20

... loading difference. As seen in Fig. 2B, production of laccase by pLac1-B increased until day 1 2. This is also supported by continuous level of expression of the recombinant lac1 transcripts during ... mgÆL )1 of wild-type laccase from the dikaryotic strain I-937 of P. cinnabarinus and 145 mgÆL )1 from the derived monokaryotic strain ss3 of P. cinnabarinus. In order...

Ngày tải lên: 17/03/2014, 11:20