Báo cáo khoa học: Activation of the plasma membrane H+-ATPase of Saccharomyces cerevisiae by glucose is mediated by dissociation of the H+-ATPase–acetylated tubulin complex docx
Báo cáo khoa học: Activation of PMCA by calmodulin or ethanol in plasma membrane vesicles from rat brain involves dissociation of the acetylated tubulin/PMCA complex pdf
... types of cells. H + -ATPase of Saccharomyces cerevisiae is similarly inhibited by interaction with acetylated tubulin. The activities of both these ATPases are restored upon dissociation of the ... Saccharomyces cerevisiae by glucose is mediated by dissociation of the H + -ATPase–acetylated tubulin complex. FEBS J 272, 5742–5752. 6 Beltramo DM, Nu...
Ngày tải lên: 23/03/2014, 07:20
Báo cáo khoa học: Activation of the plasma membrane H+-ATPase of Saccharomyces cerevisiae by glucose is mediated by dissociation of the H+-ATPase–acetylated tubulin complex docx
... Campetelli et al. Activation of the plasma membrane H + -ATPase of Saccharomyces cerevisiae by glucose is mediated by dissociation of the H + -ATPase–acetylated tubulin complex Alexis N. Campetelli 1 , ... at the periphery. This is further evidence that glucose induced dissociation of the H + -ATPase–acetylated tubulin complex. H + -ATPase a...
Ngày tải lên: 23/03/2014, 11:20
Tài liệu Báo cáo khoa học: Activation loop 3 and the 170 loop interact in the active conformation of coagulation factor VIIa pdf
... cleavage of the scissile bond. This would affect FX and peptide hydrolysis similarly, supported by the similar decrease in the rate of cleavage of both types of substrates. The effect of the G372(223)A ... 296(154) [14–17]. The high specific activity of these FVIIa variants is presumably linked to a more stable burial of the N-terminus of the protease domain...
Ngày tải lên: 18/02/2014, 08:20
Tài liệu Báo cáo khoa học: Activation of the Torpedo nicotinic acetylcholine receptor The contribution of residues aArg55 and cGlu93 ppt
... location. The AChBP, which is secreted by the glial cells of the snail, Lymnaea stagnalis , is a truncated homologue of the extracellular amino terminal domains of the nAChR[see 10]. Inspection of its ... on the WT recep- tor are consistent with such a mechanism. The most parsimonious explanation of the loss of the potentiat- ing effect in the mutant rece...
Ngày tải lên: 19/02/2014, 07:20
Báo cáo khoa học: Activation of nematode G protein GOA-1 by the human muscarinic acetylcholine receptor M2 subtype Functional coupling of G-protein-coupled receptor and G protein originated from evolutionarily distant animals doc
... elegans is the best genetic model. The generation of transgenic C. elegans has been established and is easier than that of other animal models [35]. The results of this study indicate that the Ga i ... indicating that the side effect of the acti- vation of GAR-3 is limited. Furthermore, the pheno- type of gar-3 loss -of- function mutants is almost wild- type...
Ngày tải lên: 07/03/2014, 11:20
Báo cáo khoa học: Activation of activating transcription factor 2 by p38 MAP kinase during apoptosis induced by human amylin in cultured pancreatic b-cells ppt
... apparent. p38 kinase activation is related to the presence of fibrillogenic hA, and hA-induced activation of the p38 kinase pathway in b-cells is consistent with the general role of the p38 kinase pathway ... content. ATF-2 is a transcription factor whose activation can be catalyzed by either p38 or JNK, or by both [27,41]. To further clarify the role of the...
Ngày tải lên: 07/03/2014, 12:20
Báo cáo khoa học: Tumour necrosis factor-a attenuates insulin action on phosphoenolpyruvate carboxykinase gene expression and gluconeogenesis by altering the cellular localization of Foxa2 in HepG2 cells pptx
... Thus, the mechanisms involved in the regula- tion of gluconeogenic enzymes are very controversial, and it is thereby hypothesized that both of these fac- tors contribute to insulin action on glucose ... status within the cell in the given experimental conditions. Foxo1, another member of the forkhead family of transcription factors, is a very well-established mediator...
Ngày tải lên: 16/03/2014, 02:20
Báo cáo khoa học: Activation of Stat5 and induction of a pregnancy-like mammary gland differentiation by eicosapentaenoic and docosapentaenoic omega-3 fatty acids docx
... preventative effect of a dietary supplement of n-3 PUFAs to the mother on the risk of breast cancer risk for offspring has been reported. Offspring of the rat fed an n-6 PUFA diet during pregnancy ... interpretation of the data is limited by significant differences in the methods used to ascertain exposure to n-3 PUFA. Third, of particular note is the fact that n-...
Ngày tải lên: 16/03/2014, 10:20
Báo cáo khoa học: Kinetic mechanism for p38 MAP kinase a A partial rapid-equilibrium random-order ternary-complex mechanism for the phosphorylation of a protein substrate potx
... for the second-order rate con- stant of k a ¼ 10 4 m )1 Æs )1 for the binding of MgATP to p38 MAPKa gives a rate constant for the dissociation of MgATP from the enzyme of k -a ¼ 3.5 s )1 , if the ... hands because the activity of the enzyme was also affected by the presence of Triton. Isothermal titration calorimetry To lend further support to our conclusions,...
Ngày tải lên: 16/03/2014, 22:20
Báo cáo khoa học: Activation, regulation, and inhibition of DYRK1A Walter Becker1 and Wolfgang Sippl2 pptx
... work is required to dissect the full spectrum of activation modes of the different CMGC group kinas- es. However, so far there is no evidence that the cata- lytic activity of any member of the ... inhibitor of CLKs. Obvi- ously, the promiscuous behaviour of these inhibitors limits their value as tools for the analysis of signalling pathways. Nevertheless, use...
Ngày tải lên: 22/03/2014, 16:21