Báo cáo khoa học: Pentose phosphates in nucleoside interconversion and catabolism pdf
... in mammals of any kinase acting on inosine and guanosine [15–17], which further favours the channelling of purine nucleo- sides towards phosphorolysis. Interestingly, purine ribonucleoside kinases ... adenosine kinase [39]. Rib-1-P recycling also occurs in E. coli and L. lactis. In these organisms, free adenine can serve as the sole purine source. Adenine is converted into adenosine...
Ngày tải lên: 23/03/2014, 10:21
... (2008) Mapping alpha-helical induced folding within the intrinsically dis- ordered C-terminal domain of the measles virus nucleo- protein by site-directed spin-labeling EPR spectroscopy. Proteins 73, ... B, Finet S & Longhi S (2005) The intrinsically disordered C-terminal domain of the measles virus nucleoprotein interacts with the C-terminal domain of the phosphoprotein via two distinct...
Ngày tải lên: 18/02/2014, 04:20
... so-called discontinuous constituents. We have discontinuous noun phrases in (5) and (7), a discontinuous adjective phrase in (3), discontinuous verb phrases in (1) and (4), and a discontinuous adverb ... is defined as the reflexive and transitive closure D' of D, and adjacency as linear precedence without intervening nodes. A node in a tree is called terminal if...
Ngày tải lên: 09/03/2014, 01:20
Báo cáo khoa học: Intermodule cooperativity in the structure and dynamics of consecutive complement control modules in human C1r Structural biology docx
... domains of the proteases. Inter- modular and intramodular flexibilities are thought to be essential in these movements. Expression of recom- binant intact C1r [4] and its domain combinations in insect ... strands B and C, known as the ‘hypervariable loop‘, D and E, E and F, F and G, and G and H are particularly tolerant of longer insertions [19]. In multimodular proteins,...
Ngày tải lên: 15/03/2014, 23:20
Báo cáo khoa học: Structural studies of nucleoside analog and feedback inhibitor binding to Drosophila melanogaster multisubstrate deoxyribonucleoside kinase doc
... deoxynucleo- side kinases with distinct, but overlapping, substrate affinities. Thymidine kinase 1 (TK1) and deoxycytidine kinase (dCK) are found in the cytosol, and thymidine kinase 2 (TK2) and deoxyguanosine ... phosphorylate dC and other medically interesting dT, deoxyuridine and dC analogs. dGK only phosphorylates the purine deoxyribonucleosides deoxyadenosine, deoxyguanosine...
Ngày tải lên: 16/03/2014, 06:20
Báo cáo khoa học: "Talking NPCs in a Virtual Game World" pdf
... storing and querying the data. SwiftOwlim is a “triple store”, a kind of database which is specifically built for storing and querying RDF data. It provides a forward- chaining inference engine ... for the lin- guistic analysis of the user’s textual input includ- ing preprocessing such as string cleaning, part-of- speech tagging, named entity recognition, parsing and semantic interpretat...
Ngày tải lên: 17/03/2014, 00:20
Báo cáo khoa học: "Predicting Clicks in a Vocabulary Learning System" pdf
... related work in search engine ranking, a description of the study used to col- lect click data, the experiment we performed using the random forest machine learning al- gorithm and finish with ... clicked will help. This can be used for caching. In this paper, we explore applying machine learn- ing algorithms to classifying clicks in a vocabulary learning system. The primary contributi...
Ngày tải lên: 30/03/2014, 21:20
Tài liệu Báo cáo khoa học: Oral Presentations Integration of Metabolism and Survival pdf
... spectrometry. These pro- teins were: albumin, a-enolase, calgranulin B, galectin 7, myoglo- bin, myosin light chain 1 and light chain 2, and tropomyosin b-chain. Also, differences in allele frequencies ... ligase (E3) involved in ERAD. We have identified a novel VCP-inter- acting domain (VID) in gp78 and SVIP, another VCP-interact- ing protein with unknown function. VID is transfer...
Ngày tải lên: 19/02/2014, 07:20
Tài liệu Báo cáo khoa học: Combinatorial approaches to protein stability and structure pdf
... S.W., Herberich,B.,Meggers,E.,Wang,L.&Schultz,P.G.(2003) In vitro tools and in vivo engineering: incorporation of unnatural amino acids into proteins. In Translation Mechanisms (Lapointe, J. & Brakier-Gingras, L., eds), pp. 95–114. Landes ... design proteins de novo by inserting random sequences into a loop of the SH2 domain and screening for binding to the phosphotyrosyl li...
Ngày tải lên: 19/02/2014, 12:20
Tài liệu Báo cáo khoa học: "REAPING THE BENEFITS OF INTERACTIVE AND SEMANTICS*" pdf
... Parsing. In this work, I propose an intermediate point in the LC Parsing spectrum between ASLC and AELC strategies and argue that the proposed point, that I call Head-Signaled LC Parsing ... employed in enumerating the nodes in a parse tree. In Arc Eager LC (AELC) Parsing, a node in the parse tree is linked to its parent without waiting to see all its children. Arc Standa...
Ngày tải lên: 20/02/2014, 21:20