Báo cáo khoa học: Increased glucose metabolism and ATP level in brain tissue of Huntington’s disease transgenic mice pdf

... The Authors Journal compilation ª 2008 FEBS 4755 Increased glucose metabolism and ATP level in brain tissue of Huntington’s disease transgenic mice Judit Ola ´ h 1 ,Pe ´ ter Klive ´ nyi 2 , Gabriella ... reaction to be increased in HD. In extracts of the posterior brain region of control and HD mice in the presence of excess ATP, NAD + , inorga...

Ngày tải lên: 23/03/2014, 10:20

... transporters and are involved in Na + binding [19]. Also present are conserved residues D32 in the first TMD and S321 and S324 in TMD7, thought to be involved in catecholamine binding [20]. There ... G.M., Yatin, S.M., DeLaGarza, R., Goulet, M. & Madras, B.K. (2001) Cloning of dopamine, norepinephrine and serotonin transporters from monkey brain: relevance to cocaine sen...

Ngày tải lên: 23/03/2014, 20:22

... catalytic domain (A) is flanked by a helical N-terminal domain (N), and a C-terminal domain (C) consist- ing of b strands. Domains B and B¢ are extended loops 3 and 7, respectively, protruding from ... and the catalysis of side reactions result- ing in sucrose isomer formation. Therefore, combinatorial engineering of the enzyme through random mutagenesis, gene shuffling and se...

Ngày tải lên: 23/03/2014, 11:20

... occurrences of r in T and H, divided by the number of occurrences of r in H. Separate DR matching scores are calculated for each relation r appearing both in T and H. 4 Experiments and results 4.1 ... matching score as the number of n-grams in H that match with phrases in T divided by the num- ber of n-grams in H. 1 Dependency Relation (DR) matching targets the inc...

Ngày tải lên: 19/02/2014, 19:20

... The polarity of the text is in question and the finite element indicates this. In this paper the interpretetion of the unknown elements in the question as defined by Krizkova and Helllday ... part of the inquirer and appeals to the informant to satisfy this want. (ii) [a] it i,~erts knowledge to the informant in that it informs him what the inquirer is...

Ngày tải lên: 21/02/2014, 20:20

... role against intermolecular cross-b interactions in the native protein. On the other hand, the location of His5 1in the D-strand is intrigu- ing: in native b2m, the His51 side chain points out- wards, ... grouped into two main classes: (a) geometrical irregularities, such as b-bulges, on edge b-strands, hampering intermolecular backbone interac- tions, and (b) inward-pointing charged...

Ngày tải lên: 06/03/2014, 00:20

... Domain structure of dynamins and dynamin-related proteins (DRPs). GED, GTPase effector domain; MD, middle domain; PH, pleckstrin homology; PRD, proline- and arginine-rich domain. S. Thoms and ... domain (GED), which activates GTPase activity and mediates self-assembly, and a proline and arginine-rich domain (PRD) that mediates interactions with SH3 domains of effector proteins...

Ngày tải lên: 07/03/2014, 21:20

... translation she has in mind and the total number of words in the sentence. In this context, a word-stroke is interpreted as a single ac- tion, in which the user types a complete word, and is assumed ... esti- mation, from the training set, of different statisti- cal models, which are in turn combined in a log- linear fashion by adjusting a weight for each of them by mean...

Ngày tải lên: 07/03/2014, 22:20

... labelers an- notated the training and test sets; none of the au- thors were involved in labeling the test set. Table 1 presents information about the number of instances of each of these classes found. 4 ... conversations, yielding 85 utterances con- taining “you”; the task was reported to be easy, and the kappa was 100%. We then annotated a total of 42 conversations for train...

Ngày tải lên: 08/03/2014, 03:20

... Resolving Translation Ambiguity and Target Polysemy in Cross-Language Information Retrieval Hsin-Hsi Chen, Guo-Wei Bian and Wen-Cheng Lin Department of Computer Science and Information Engineering ... document would mention investigations either in the U.S. or abroad of people suspected of evading U.S. income tax laws. Of particular interest are investigations involving...

Ngày tải lên: 17/03/2014, 07:20