Báo cáo khoa học: Identification and characterization of multiple species of tenascin-X in human serum doc

... seen in the putative T-box DNA-binding domain of t-bet, the STAT protein inter- action domain, STAT protein all-alpha domain, STAT protein DNA-binding domain and SH2 domain of stat6, and the zinc-finger ... expression of T-bet has been seen within a wide variety of tissues and cells in the Ginbuna crucian carp [27] and, in mammals, in the lung tissue of mouse and spl...

Ngày tải lên: 16/02/2014, 09:20

... representing the 5¢- and 3¢-UTRs are shown in white in the genomic gene and the cDNA. Intron size in bp, domain size in bp and domain size in amino acids are indicated at the bottom of each schematic ... consisting of both free-living and host-dependent stages. The signaling mechanisms underlying the growth and development of S. mansoni during these stages have remai...

Ngày tải lên: 18/02/2014, 16:20

... only in RARs (NR1B) [17] (Fig. 4C). The splice site of A DNA binding domain B Ligand binding domain Fig. 1. Sequence alignment. (A) Alignment of DNA binding domain (C domain) and its C-terminal ... SmNR1(Ile247-Ser372) and SmRXR1(Glu251-Asn376) in vitro. DNA binding of a protein containing 20 amino acids at the 5¢ end of the DBD, the DBD and the 40 amino acids at the 3¢ en...

Ngày tải lên: 07/03/2014, 11:20

... plasmid and a virus. Mol Microbiol 34, 217–226. 29 Bradford M (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. ... redox-active cysteine, the resol- ving cysteine (Cys-S R ). In typical 2-Cys, S p at the N terminus and S R at the C terminus of the protein belong to different subunits a...

Ngày tải lên: 07/03/2014, 12:20

... Xenopus protein has a long N-terminal extension, and so encodes a protein of about 70 kDa instead of 48 kDa. Screening of the human EST database with the cDNA sequences comprising this N-terminal extension ... M., Fujisawa,H.,Kleihues,P.&Walter,G.(2001)Reducedexpres- sion of the Aa subunit of protein phosphatase 2A in human gliomas in the absence of mutations in th...

Ngày tải lên: 08/03/2014, 08:20

... that triafestin-1 and triafestin-2 inhibit the activation of the kallikrein–kinin sys- tem by inhibiting the reciprocal activation of factor XII and prekallikrein, and subsequent release of bradykinin. Binding ... leading to inhi- bition of the intrinsic coagulation pathway. Triafestin inhibits FXII and PK reciprocal activation and bradykinin generation To investigate inhibi...

Ngày tải lên: 16/03/2014, 05:20

... (a) maintenance of colloid osmotic pressure; (b) binding and transport of a wide variety of metabolites including steroids, fatty acids, bilirubin, tryptophan and hemin; (c) sup- plying an amino ... undigested HSA. Changes in intensities of HSA bands relative to the band of starting point of digestion are shown. A. Kawakami et al. Characterization of oxidized human se...

Ngày tải lên: 16/03/2014, 13:20

... domain of CP2. Our list of polypeptides that bind to CP2 shows a preponderance of histidines, implying the importance of this amino acid residue in the CP2-binding motif of proteins that interact ... 2005 FEBS Recognition of proteins containing CP2-binding motifs and verification of the CP2-binding ability of REST and YY1 that contain the HXPR motif As stated above, none...

Ngày tải lên: 16/03/2014, 18:20

... kDa band in T cells. A Cb-specific antibody anti-Cb(SNO157) (vi) recognized the 47 kDa band in T-cells, and the 40- and 47 kDa protein bands in Jurkat cells. (C) Lin- ear depiction of Ca1, Cb1 and ... Skalhegg BS (2004) Induction of Cbeta splice variants and formation of novel forms of protein kinase A type II holoenzymes during retinoic acid- induced differentiation of...

Ngày tải lên: 16/03/2014, 18:20

... pocket plays a role in substrate discrimination against binding of the 5-OH group of Kdo and in favour of the N-acetyl group of Neu5Ac and, although these residues are conserved in CNS enzymes, none ... [12–18,20]: *, CTP-binding residue of the P-loop; (*), CTP-binding residue; ^, Neu5Ac-binding residue; #, Neu5Ac-binding residue forming part of the hydrophobic pocket; °...

Ngày tải lên: 22/03/2014, 21:21