Báo cáo khoa học: An internal ribosome entry site mediates the initiation of soluble guanylyl cyclase b2 mRNA translation potx

... both transcription and scanning translation. It also suggests that the initiation of sGC b2 translation is through an alternative mechanism that is less efficient than scan- ning translation. The ... 2008) doi:10.1111/j.1742-4658.2008.06505.x The soluble guanylyl cyclases (sGC), the receptor for nitric oxide, are hete- rodimers consisting of an a- and b-subunit. Thi...

Ngày tải lên: 23/03/2014, 07:20

... Model of the 3D structure of the neutral protease from Bacillus stearothermo- philus, including the position of the disulfide bridge in mutant G8C ⁄ N60C. The model was created on the basis of the ... k B , h and R as Boltzmann’s constant, Planck’s constant and gas constant, respectively, and T and DG # as absolute temperature and Gibbs free energy of activation, respec...

Ngày tải lên: 19/02/2014, 17:20

... similar in the fractions in the periphery [20]. In the absence of Itk, there are reduced numbers of iNKT cells in the thymus and periphery [21]. More detailed analysis of the development of Itk-null i ... including the sec- ondary lymphoid organs and the epithelial layers of tissue such as the skin, intestinal epithelium and lung. The different subsets of cd T ce...

Ngày tải lên: 28/03/2014, 22:21

... reflect the energy sta- tus of the animal. These nutrients too can provoke changes in feeding behavior and energy expenditure. For example, the hypothalamus can sense and respond to fluctuations in the ... lipid nutrient sensing in the brain and is an example of an enzyme that can sense and respond to the nutritional environment. The major challenge to understanding the...

Ngày tải lên: 14/02/2014, 22:20

... interval, there are six types of serial-order process that can occur and affect the state of the process. The most important aspect of the control is that all of the serial order computations can ... mathematically better defined than through other methods, because it enables one to develop a broader perspective of the questions within an analysis of the hyp...

Ngày tải lên: 21/02/2014, 20:20

... robust (i.e. makes use of retry and parallelisation) and the error is confined to a WS (i.e. it does not affect the rest of the workflow). An instance of Biocatalogue and one of my- Experiment have ... On the other hand, GrAF can be used as a pivot format between other for- mats (Ide and Bunt, 2010), e.g. there is software to convert GrAF to UIMA and GATE formats (Ide and Sude...

Ngày tải lên: 22/02/2014, 03:20

... LC-MS ⁄ MS analysis. Of 22 (17 nonredundant) candidate substrates identified, the proteolytic process- ing of vinculin, lysyl oxidase, collagen type V and annexin A1 was analysed by means of immunoblotting ... PAGE-based image analyses of the third quadrant. Fig. S3. 2D IEF ⁄ SDS ⁄ PAGE-based image analyses of the fourth quadrant. This supplementary material can be found in th...

Ngày tải lên: 07/03/2014, 06:20

... from the other bran- ches, which was indeed predicted. The other main group, obtained 97% of the time in 20 740 explored trees, contained the DIDO PHD sequences clustered with the PHF and the ... yeast and other organisms. These homologues have a role in DNA regulation and chromatin stability, and form part of higher com- plexes linked to active chromatin. Further domain compo...

Ngày tải lên: 07/03/2014, 21:20

... feature in the regulation of cholesterol transport by AA and the release of AA in a specialized compartment of the cells could offer novel means for understanding the regulation of steroid synthesis, ... through the CPT1- dependent pathway. The specificity of this mechanism to release AA inside the mitochondria is shown by the fact that the content of labeled AA i...

Ngày tải lên: 16/03/2014, 12:20

... upstream from the start of the poly(A) + tail. Fig. 2. HPLC analysis of the intrinsic ligand of Papi lio RBP. The lig- ands were extracted from Papilio RBP purified from the soluble fraction of the dark-adapted ... the stained bands using a Sharp JX-350 image scanner. We further analyzed the isomer composition of the intrinsic ligands of Papilio RBP extracted se...

Ngày tải lên: 17/03/2014, 03:20