Báo cáo khoa học: New insights into evolution of crustacean hyperglycaemic hormone in decapods – first characterization in Anomura pdf

... (2008) 103 9–1 052 ª 2008 FEBS. No claim to original French government works New insights into evolution of crustacean hyperglycaemic hormone in decapods – first characterization in Anomura Nicolas ... the moult- inhibiting hormone (MIH) [13]. Type II subfamily peptides include moult-inhibiting hormone (MIH), vitellogenesis-inhibiting hormone (VIH) and...

Ngày tải lên: 23/03/2014, 07:20

... typical binding fold of ThDP enzymes, comprising three domains of the a ⁄ b type, designated as the PYR domain (residues 1–1 90), the R domain (residues 19 1–3 68) and the PP domain (residues 36 9–5 64) ... S-acetyl pantetheine part of acetyl CoA, and consequently the model for the inhibitor remains incomplete. The nitrogen atom of the amino group of the adenosine ring of P...

Ngày tải lên: 06/03/2014, 11:20

... 6–8 ) and glycine/NaOH (pH 9–1 1). The remaining activity of 5 ng of RVV-X was determined by measuring the clotting time on a coagulation analyser. Biotinylation of RVV-X and far-western blotting The ... modeling reveal Echis coagulation factor IX/factor X-binding protein has the Ca-binding properties and Ca ion-independent folding of other C-type lectin-like proteins. FEBS Lett 5...

Ngày tải lên: 07/03/2014, 06:20

... k a ÁC i ð3Þ In this work, the rate of P-gp-associated efflux of rhodamine was calculated at the steady-state, taking into account the following points: (a) the diffusion (in ux and efflux) of rhodamine ... cells in K + -buffer were incubated with rhodamine. In fact, when cells are incubated with rhodam- ine, before reaching the steady state, rhodamine continu- ously enters into...

Ngày tải lên: 08/03/2014, 08:20

... ‘hydrophobic platform’ involved in RNA recognition. They had observed such a mode of KH domain–RNA interaction in the cocrys- tal structure of the KH3 domain of NOVA bound to an in vitro selected ... to associate into ribonuclear protein (RNP) particles of abnormal density, perhaps by disruption of protein– protein interactions [15]. To summarize, three main hypotheses have...

Ngày tải lên: 30/03/2014, 15:20

... on nevirapine binding which we suggest to be optimiza- tion of inhibitor ring stacking interactions with Tyr181. Lys101Glu provides an example of an indirect mechanism of inducing drug resistance in ... structural consequences of the mutant side-chain movement include partially disrupting the hydrogen bond network involving nevi- rapine, water and side-chain ⁄ main-chain interaction...

Ngày tải lên: 16/03/2014, 13:20

... here. Modes of binding of E-64 with ervatamin-A and ervatamin-C The modes of binding of E-64 with ervatamin-A and ervatamin-C have been analyzed and compared with the structures of other complexes of ... the surface of domain L con- taining the active site Cys. The S3–P3 interactions are mainly governed by side chain interactions, and accordingly the amino-4-guanidinobutane (P3)...

Ngày tải lên: 18/02/2014, 16:20

... University, New York W30 3–1 B (WT) MATa, ade 2–1 , his 3–1 1,15, trp 1–1 , leu 2–3 ,112, ura 3–1 , can 1–1 00 Gift from A. Tzagoloff, Columbia University, New York MES8 (D6) MATa, ade 2–1 , his 3–1 1,15, trp 1–1 , leu 2–3 ,112, ura 3–1 , ... leu 2–3 ,112, ura 3–1 , can 1–1 00, qcr6D::LEU2 [37] VZ1 (D7) MATa, ade 2–1 , his 3–1 1,15, trp 1–1 , leu 2–3 ,...

Ngày tải lên: 19/02/2014, 12:20

... (Fig. 2) [ 9–1 3]. The CCM1 gene contains 16 coding exons which encode for Krit1, a 736-amino acid protein containing three ankyrin domains and one band 4.1 ezrin radixin moesin (FERM) domain. CCM2, ... C-terminal part of the phosphotyro- sin binding domain of CCM2 [12]. This mutation has been shown to abolish the interaction of CCM2 and CCM1, strongly suggesting its causality [25]. O...

Ngày tải lên: 15/03/2014, 10:20

... a normal number of cells, but instead of building into concentric layers to form the walls of the heart, the myocardial cells form into a single layer, resulting in a dilated, thin-walled heart ... insights into a better understanding of disease mechanism. In this minireview, we discuss the contributions of animal models to our growing understanding of the biology of...

Ngày tải lên: 15/03/2014, 10:20