Báo cáo khoa học: Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics pdf
Báo cáo khoa học: Structural flexibility in Trypanosoma brucei enolase revealed by X-ray crystallography and molecular dynamics pdf
... compilation ª 2007 FEBS 5089
Structural flexibility in Trypanosoma brucei enolase
revealed by X-ray crystallography and molecular dynamics
Marcos V. de A. S. Navarro
1,
*
,‡
, Sandra M. Gomes Dias
1,
*
,§
, ... of the inhibition of
T. brucei enolase by FPAH.
Fig. S1. Lineweaver–Burk plots for T. brucei enolase in
the presence of FPAH.
Structural flexi...
Báo cáo khoa học: Structural diversity in lipopolysaccharide expression in nontypeable Haemophilus influenzae Identification of L-glycero -D-manno-heptose in the outer-core region in three clinical isolates potx
... doi:10.1046/j.1432-1033.2003.03399.x
Molecular structural studies of LPS from H. in uenzae
strains [9–19] have resulted in a structural model consisting
of a conserved phosphoethanolamine (PEtn)-substituted
triheptosyl inner-core ... (
D
,
D
–Hep) [13]. In NTHi strains SB 33
and 176 [16,18], disubstitution by b-
D
-Glcp (at O-4) and
PCho (at O-6) occurs, while in strain RM1...
Báo cáo khoa học: Structural features in the C-terminal region of the Sinorhizobium meliloti RmInt1 group II intron-encoded protein contribute to its maturase and intron ppt
... 6097–6100.
Supplementary information
The following supporting information is available:
Fig. S1. Retrohoming in vivo of wild-type intron and
C-terminal region mutant derivatives using RmInt1-
engineering constructs ... Group II
intron-encoded proteins are multifunctional and contain an N-terminal
reverse transcriptase domain, followed by a putative RNA-binding domain
(domain X) associ...
Báo cáo khoa học: Structural flexibility of the methanogenic-type seryl-tRNA synthetase active site and its implication for specific substrate recognition pptx
... shown) revealed the ordering of 394–410
loop residues and interactions with Gln400, despite
replacing Trp396 with alanine.
The in uence of mutations in the serine-binding
pocket on magnesium binding
The ... binding of ATP and the amino acid
substrate in the active site are linked, and incorrect
binding of ATP can affect serine binding and vice
versa [22]. Asn435, together with...
Tài liệu Báo cáo khoa học: Nuclear receptors in the mosquito Aedes aegypti Annotation, hormonal regulation and expression profiling ppt
... longest amino acid sequences that included
the DNA binding, hinge and ligand-binding domains
were used for this analysis, except for the Knirps fam-
ily members that lack the LBD. In D. melanogaster,
Table ... experiment (right), 5 day PV fat bodies were incubated in CM for 30 min and established as initial time point
(0 h); then were incubated in CM or with 20E for 4 and 16 h, or...
Báo cáo khoa học: Protein transport in organelles: Dual targeting of proteins to mitochondria and chloroplasts ppt
... mitochondrial and chloroplastic
targeting signals in terms of arginine and serine con-
tent (i.e. not as high as in mitochondrial targeting
signals) and may be slightly enriched in hydrophobic
residues. In ... provided, and
the insights that may be gained from a greater under-
standing of the mechanism of dual targeting for the
targeting of location-specific proteins is discuss...
Báo cáo khoa học: Functional symmetry in the isolated domain demonstrated by N-ethylmaleimide labelling pdf
... engineering, expression and purification of
single-cysteine-containing proteins comprising either the
C-terminal NBD or the N-terminal NBD as fusions to
Escherichia coli maltose-binding protein ... of
P-glycoprotein contains only a single cysteine in the
Walker-A motif [43]. Thus, MBP-NBD-Nter is a 75-kDa
fusion protein containing a single cysteine residue located in
the ATP-binding pock...
Báo cáo khoa học: Expression of heme oxygenase-1 is repressed by interferon-c and induced by hypoxia in human retinal pigment epithelial cells pot
... hypoxia may increase tran scription of the HO-1
gene through a certain protein factor in RPE cells. These
results indicate that RPE cells maintain retinal homeostasis
by repressing or inducing the ... urvival and
maintenance of RPE in the adult retina. On the other
hand, we have shown that HO-1 expression is reduced in
human cell lines by treatmen t with interferon-c [26,27] or b...
Báo cáo khoa học: Structural basis for the interaction between dynein light chain 1 and the glutamate channel homolog GRINL1A docx
... with the
laminar organization revealed by negative staining and
immunogold labelling [26].
A non-consensus sequence within GRINL1A is
responsible for DYNLL1 binding in the canonical
mode
In this ... absolutely
required for binding and is most likely involved in
increasing binding affinity. G426 of GRINL1A occu-
pies the equivalent position to this glutamine, which is
typically in...
Báo cáo khoa học: Structural requirements for Caenorhabditis elegans DcpS substrates based on fluorescence and HPLC enzyme kinetic studies pdf
... containing HIT with three
histidines separated by hydrophobic residues (His-u-
His-u-His-u). Structural analysis has revealed that
HIT proteins exist as homodimers containing nucleo-
tide-binding ... these crucial amino acids resulted in enzyme
inactivation or a significant decrease in activity [20].
Two amino acids, Asp205 and Lys207, are involved in
interactions with the 2¢-O-...
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