... 20–564), and the model is composed of residues 25–540. The overall structure of the model of IPU and the mutated residues in this study areshown in Fig. 3. To elucidate the mechanism of the substrate ... 372, and 373are the potential catalytic r esidues of I PU. Also, Trp425 of Dex49A, which is the corresponding residue of Trp402 of IPU, is reportedly located in the vicinity of the active site and ... vulgaris, TVA II (PDB ID, 1BVZ;Z score of 3.2) [45] was a solution in the Dali result. It is likely that the inte rface between N-terminal and b-he licaldomains participate in binding of the...